Heterocephalus glaber (naked mole-rat): 101705662
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Entry
101705662 CDS
T02812
Symbol
Idh1
Name
(RefSeq) isocitrate dehydrogenase (NADP(+)) 1, cytosolic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00020
Citrate cycle (TCA cycle)
hgl00480
Glutathione metabolism
hgl01100
Metabolic pathways
hgl01200
Carbon metabolism
hgl01210
2-Oxocarboxylic acid metabolism
hgl01230
Biosynthesis of amino acids
hgl04146
Peroxisome
hgl05230
Central carbon metabolism in cancer
Module
hgl_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hgl_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
101705662 (Idh1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101705662 (Idh1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
101705662 (Idh1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101705662 (Idh1)
Enzymes [BR:
hgl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
101705662 (Idh1)
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Motif
Pfam:
Iso_dh
XRN1_D2_D3
Motif
Other DBs
NCBI-GeneID:
101705662
NCBI-ProteinID:
XP_004851192
UniProt:
A0AAX6PH47
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Position
Un
AA seq
414 aa
AA seq
DB search
MSKKIHGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIKNRDATNDQVTKDA
AKAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPRDGVQKVTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSIAQGYGSLGMMTSVLICPDG
KTVEAEAAHGTVTRHYRMYQKEQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaaaaaatccatggcggttctgtggtagagatgcaaggagatgaaatgacacga
ataatttgggaattgattaaagaaaaactcatttttccctatgtggaactggatctgcat
agctatgacttaggtataaagaatcgggatgccaccaatgaccaggtcaccaaggatgct
gcaaaagctataaagaagtacaacgttggtgtcaagtgtgccaccatcacccctgatgag
aagagagttgaggagttcaagttgaaacaaatgtggaaatcaccaaatggcaccatccga
aatattctgggtggcactgtcttcagggaagctattatctgtaaaaatatcccccggctt
gtgactggatgggtaaaacccatcatcatcggtcgtcacgcctatggggatcaatataga
gcgactgattttgttgttcctgggcctgggaaagtagagataacctacacaccaagggat
ggagtccagaaggtgacatacctggtccataactttgaagagggtggtggtgtcgccatg
gggatgtataatcaagataagtcaattgaagactttgcacacagttccttccaaatggcg
ctgtctaagggttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
ggacgctttaaagacatctttcaggagatatatgacaagcagtacaaatcccagtttgaa
gcccagaagatctggtatgagcacaggctcattgatgatatggtggcccaagctatgaag
tcagagggaggcttcatctgggcctgtaaaaactacgatggcgatgtacagtcagattct
attgctcaaggttacgggtcccttgggatgatgaccagcgtgctgatttgtccagatggc
aaaacagtagaagcagaggctgcccatgggactgttacacgccactaccgcatgtaccag
aaggaacaggagacctccaccaatcctattgcttccatttttgcctggtccagagggttg
gcccacagagcaaagcttgataacaacaccgagctcagcttctttgcaaaagctttagaa
gaagtctgcattgagaccattgaggctggctttatgaccaaggacttggctgcttgcatt
aaaggtttacccaatgtgcaacgttctgactacttgaatacgtttgagttcatggacaaa
cttggagaaaacttgaagataaaactagctcaggccaaactttaa
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