Heterocephalus glaber (naked mole-rat): 101705849 Help Entry 101705849         CDS       T02812                                  Symbol Pla2g4e Name (RefSeq) phospholipase A2 group IVE   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00564   Glycerophospholipid metabolism hgl00565   Ether lipid metabolism hgl00590   Arachidonic acid metabolism hgl00591   Linoleic acid metabolism hgl00592   alpha-Linolenic acid metabolism hgl01100   Metabolic pathways hgl04010   MAPK signaling pathway hgl04014   Ras signaling pathway hgl04072   Phospholipase D signaling pathway hgl04217   Necroptosis hgl04270   Vascular smooth muscle contraction hgl04370   VEGF signaling pathway hgl04611   Platelet activation hgl04664   Fc epsilon RI signaling pathway hgl04666   Fc gamma R-mediated phagocytosis hgl04724   Glutamatergic synapse hgl04726   Serotonergic synapse hgl04730   Long-term depression hgl04750   Inflammatory mediator regulation of TRP channels hgl04912   GnRH signaling pathway hgl04913   Ovarian steroidogenesis hgl04921   Oxytocin signaling pathway hgl05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     101705849 (Pla2g4e)    00565 Ether lipid metabolism     101705849 (Pla2g4e)    00590 Arachidonic acid metabolism     101705849 (Pla2g4e)    00591 Linoleic acid metabolism     101705849 (Pla2g4e)    00592 alpha-Linolenic acid metabolism     101705849 (Pla2g4e)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101705849 (Pla2g4e)    04014 Ras signaling pathway     101705849 (Pla2g4e)    04370 VEGF signaling pathway     101705849 (Pla2g4e)    04072 Phospholipase D signaling pathway     101705849 (Pla2g4e)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101705849 (Pla2g4e)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101705849 (Pla2g4e)    04664 Fc epsilon RI signaling pathway     101705849 (Pla2g4e)    04666 Fc gamma R-mediated phagocytosis     101705849 (Pla2g4e)   09152 Endocrine system    04912 GnRH signaling pathway     101705849 (Pla2g4e)    04913 Ovarian steroidogenesis     101705849 (Pla2g4e)    04921 Oxytocin signaling pathway     101705849 (Pla2g4e)   09153 Circulatory system    04270 Vascular smooth muscle contraction     101705849 (Pla2g4e)   09156 Nervous system    04724 Glutamatergic synapse     101705849 (Pla2g4e)    04726 Serotonergic synapse     101705849 (Pla2g4e)    04730 Long-term depression     101705849 (Pla2g4e)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101705849 (Pla2g4e)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101705849 (Pla2g4e) Enzymes [BR:hgl01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      101705849 (Pla2g4e) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 ICAT Motif Other DBs NCBI-GeneID:  101705849 NCBI-ProteinID:  XP_012933904 UniProt:  A0AAX6RLY8 LinkDB All DBs Position Un AA seq 861 aa AA seqDB search MDEAGMDPLVLGSQCDLGTDALLPWSPQRYEEDSKWGDTQDLEALPRPPVLPVAPCTSQE GQSPCHLLTVRVIQMKNVRQADLLSQTDCFVSLWLPTASSEKVRTRTISNCPNPEWNETF SFQIQTQVKNVLELSVCDEDPITPNDHLLIVLYDLSKLCFRKKVHVKFPLNPEGLEELEV EFLLAESPSPAETLITNGVLVSRQVSCLEVHAESRRQRKRKKMKDLLVTVTESFENTQRI SPRREPCCPDPSSFHYPKYFQPCLQVAVPKSHWDCLLSCCSTHKSSPVCQPLDCLSDSQA VTLPVNENYELHMKSTPCPDTLDVRLGFNLCPEELKFLEKRKVVVAEALKQVLQLEEDLA EDEVPLIAIMATGGGARSMTSLYGHLLGLQKLNLLNCSSYISGLSGATWTMATLYQDPEW SSKDLQSAIFEARRHAVKDKMPSLFPDQLLKFKEELRQRTQEGYKVTFTDFWGLLLESCL GDESSEYKLSDQRAAVCQGQNPLPIYLTINVKDDVSNQDFREWCEFSPYEVGMQKYGAFI PPELFGSEFFMGRLMKRIPESRMCYMLGLWSSIFSLNLLDAWNLCNTSEEFLHRWTREKV HDIEDEPLLPEIPKCDANILETSVVNPASWLSNTFREVLTYRSFGSEFHNFMYGLQLHTG YLRNSHFQKWKDTVLDRFPNQLTEFAKHLCLLDTAFFVNSSYAPLLRQERKADLVIHLNY SAGSQTKPMKQTCEYCTEQGIPFPSYGIEDDDQNLQECYLMEQPQDPDVPVVAFFPLIND TFQKYKAPGVERSPEEMELGQVNIYGPKSPYATKELTYTEAAFDKLVKLSEYNILNNKDK LLQALRLAVEKKKRLRSPCPS NT seq 2586 nt NT seq  +upstreamnt  +downstreamnt atggatgaggctggaatggacccgctggtcttgggaagccaatgtgacctgggaactgat gcacttcttccttggagcccccaaaggtatgaagaagacagcaagtggggagacacacag gacctggaggctctccctcgcccacctgtgcttcccgtggccccttgcacctctcaggag ggccagtctccatgccacctgctgacagtgagggtcatccagatgaaaaatgtccgccag gctgatctattgagccaaacagactgctttgtgagcctctggctgcccactgcctcttct gagaaggtgaggaccaggaccatctccaactgcccaaacccagagtggaacgaaaccttc agcttccagatccagacccaagtgaagaacgtgctagagctgagcgtttgtgatgaagac ccaataacacccaacgaccatctcttgatagttctctatgacctctccaagctctgcttc cggaagaaagtccatgtgaagttcccactcaacccagagggcttggaggagctggaggtg gagttcttgctggcagagagtccctctccggcggagaccctcatcaccaatggcgtgctg gtgtctcgccaagtctcttgcctagaggttcacgcagaatccaggcggcagaggaagagg aagaaaatgaaagacctgttggtgacagtgactgaatccttcgagaacacccagcgcatc tcaccccgcagggagccctgctgccctgacccttcctccttccactaccccaagtacttt cagccctgcttgcaggtggctgtgcccaagagccactgggactgtttgctcagctgctgc agtacacataagagcagtcctgtctgccagcccctcgactgcctttctgacagccaagcc gtgaccctgcctgtgaatgagaattatgaactacacatgaagtccacaccctgccctgac acactagatgtacgactgggcttcaacctatgccccgaggagctcaaatttctggagaag cggaaggtggtggtggctgaggcactgaagcaggtgctgcagctggaggaggacctggct gaggacgaggtacctctgatagccatcatggccaccgggggtggagcaaggtccatgacc tccctgtacggccacctgctgggactgcagaagctgaacctcctgaactgcagcagttac atctccggcctgtctggggccacctggacgatggctactttgtaccaagatccggagtgg tcctccaaagacctgcagtctgctatctttgaggcccggagacatgccgtcaaagacaag atgccctccctattcccagaccagctcctcaaattcaaggaggaactccggcagcgcacc caggaaggctacaaggtcacctttacagacttctggggcctgctgcttgagtcctgtctg ggggatgagagtagtgagtacaaactatcagaccagcgtgctgctgtgtgccagggccag aaccccctgcccatctacctcaccatcaatgtcaaggatgatgtaagcaaccaggacttc agagagtggtgtgagttctccccctacgaagtggggatgcagaagtacggggccttcatc ccacccgaactcttcggctctgagttcttcatgggacggctgatgaagaggatccccgag tcacggatgtgctacatgctaggtttgtggagcagcatcttctccctgaacctactcgac gcctggaatctgtgcaacacctcagaggagtttttgcaccgatggacgagggagaaagta catgacatcgaagacgagccactcttgcctgaaatccccaaatgtgatgctaacatcctg gagacctcggtagtgaacccagcatcctggctgtccaatactttccgagaagtcctcacc taccggtccttcgggtctgagttccacaacttcatgtacgggctgcagctacacactggg tatctccgcaacagccacttccagaagtggaaagacacagtgctggaccgctttccaaac cagctgacagagtttgccaaacacttgtgcctgctggacacggcattcttcgtcaactcc agctatgcacccctcctcaggcaagagagaaaagctgacctcgtcatccacctcaattac tccgctgggtcccagacgaagcccatgaaacagacctgcgagtactgcactgagcagggg atccccttccccagctatggcatcgaggatgatgatcaaaacctccaggagtgctacctg atggagcagccccaggaccccgatgtgcccgtcgtggctttcttcccgctcatcaacgac accttccagaagtacaaggcaccgggcgtggagcggagccccgaggagatggagctgggc caagttaacatttatggccccaaatctccctatgccaccaaggagctgacatacacggaa gctgcctttgacaagctggtgaagctctcagagtacaacatcctgaataacaaagacaag ctcctccaggccctgcgcctggcagtggagaagaagaaacgcctgaggagcccatgtcct tcctag

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