Heterocephalus glaber (naked mole-rat): 101708424 Help Entry 101708424         CDS       T02812                                  Symbol Tsc1, Hamartin Name (RefSeq) tuberous sclerosis 1   KO K07206   tuberous sclerosis 1 Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl04072   Phospholipase D signaling pathway hgl04140   Autophagy - animal hgl04150   mTOR signaling pathway hgl04151   PI3K-Akt signaling pathway hgl04152   AMPK signaling pathway hgl04211   Longevity regulating pathway hgl04218   Cellular senescence hgl04714   Thermogenesis hgl04910   Insulin signaling pathway hgl05163   Human cytomegalovirus infection hgl05165   Human papillomavirus infection hgl05168   Herpes simplex virus 1 infection hgl05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     101708424 (Tsc1)    04151 PI3K-Akt signaling pathway     101708424 (Tsc1)    04152 AMPK signaling pathway     101708424 (Tsc1)    04150 mTOR signaling pathway     101708424 (Tsc1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101708424 (Tsc1)   09143 Cell growth and death    04218 Cellular senescence     101708424 (Tsc1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101708424 (Tsc1)   09149 Aging    04211 Longevity regulating pathway     101708424 (Tsc1)   09159 Environmental adaptation    04714 Thermogenesis     101708424 (Tsc1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101708424 (Tsc1)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     101708424 (Tsc1)    05163 Human cytomegalovirus infection     101708424 (Tsc1)    05165 Human papillomavirus infection     101708424 (Tsc1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  101708424 NCBI-ProteinID:  XP_004849103 UniProt:  A0AAX6PCW4 LinkDB All DBs Position Un AA seq 1165 aa AA seqDB search MAQPGNVGELLSMLDSPTLGVRDDVMAVFKENLNSDRGPMLVNTLVDYYLETNSQPVLHI LTTLQEPHDKHLLDKINEYVGKAATRLSILSLLGHVVRLQPSWKHKLSQAPLLPSLLKCL KVDTDVVILTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVTEIYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH ELDPRRWKKLETHDVVIECAKISLDPTEASYEDGYSVSHQLSTRFPQRPMDVTTSPYVDT QNSYGNAASTPCSASRLTLFSTPGQLAHPSSFPSTRPLPEPPKATLWSPSMVCGMTTPPT SPGNVPPDLSHSYSKVFGTAGGKGTPLGTPATSPPPALPCHPDDYLHISLPQVVATPPRK EERGESARPSLHRQPHLPSDRGLEELPGPKGSVTLSDLPGFLGDLASEEDSIEKDKEEAA ISKELSEITPAEAEPVVPRGGFDSPFYGDSLPGSQRKTHSAASGMQGSIANPEPLHSSLD KLGPDTPKQAFTPIDLPCGGADTSPAGDRAPQTSLATSILTPSPCKIPPQRGVDFGSGQP PPYDHLFEVALPKTACHFVSKKTEELLKKAKGSTEEDSAPSTSPMEVLDRLIQQGADAHS KELSKLSLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLR KVIRAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYSQLQEQRDTVVTQLHSQIRQ LQHDREEFYNQSQELQTKLEDCRSMIAELRVELKKANSKVCHTELLLSQVSQKLSNSESV QQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQNQR LDTSQKRISELESHLAKKDHLLLEQKKYLEDVKAQARGQLQAAESRYEAQKRITQVFELE ILDLYGRLEKDGLLQKLEEEKPEAAEAAEERLDCCYDGCSDPMKGHKEEASGHNGETKTP GPGSMRGSSGGRGAGGGGSSSSSSELSTPEKPPSQRAGPFSSRREATVGEPTTSIPTVGS LPSSKSFLGMKARELFRNKSESQCDEDGMSICSLPESLKTDLGKDSGVEAKTSLNLDGPH PSPPSLDSVGQLRIMDYNEARHEHS NT seq 3498 nt NT seq  +upstreamnt  +downstreamnt atggcccagccagggaatgtcggggagctgctctccatgctggattctcccacactgggt gtgcgtgatgatgtgatggctgtctttaaagagaatctcaactctgaccgtggtcctatg cttgtaaacacattggtggattattacctagaaaccaattctcagccggtattgcacatc ctgactaccttgcaagagccacatgataagcaccttttggacaaaatcaatgaatatgtg ggcaaagccgccacccgtttatccatcctgtcgttgctggggcatgtggtgagactgcag ccgtcgtggaagcataagctctctcaagcacctctcttgccttctttactaaagtgtctc aaggtggacactgacgtcgtcatcctcacaacaggtgtcttggtgttgatcactatgcta cccatgattccacagtctgggaagcagcatcttcttgatttctttgatatctttggccgt ctttcctcgtggtgcctgaaaaaaccaggccacgtgacagaaatctatcttgtccatctc catgccagtgtttatgccctcttccatcgcctttatgggatgtacccttgcaactttgtc tcctttctgcgttctcactacagtatgaaggaaaacttggagacttttgaagaagtggtc aagccaatgatggagcatgtgcgaattcacccggaattagtgactggatccaaggaccat gaactggaccctcgaaggtggaagaaattagaaactcatgatgttgtcatagagtgtgcc aaaatctctctggaccctacagaagcctcatatgaagatggctactctgtgtctcaccag ctctccacccgcttccctcagcgtcccatggatgtcaccaccagcccttatgttgacaca cagaatagctatgggaatgctgcctccaccccttgctccgcctcccggctgacgttgttc agtacgccagggcagctagctcacccttcgagtttcccgtctacacggccgttacctgag ccgccaaaagctactctttggagcccatccatggtttgtgggatgaccacccccccgacg tctcctggaaatgtcccacctgacctgtcacactcgtacagtaaagtctttggaacagcc ggtggaaaaggaactcctctggggacccccgcaacctcccctcctccagccctgccctgc cacccggatgactacctgcacatctcactcccccaggtcgtggccacaccccccaggaag gaggagagaggagagtctgcgcggccgagtctccacaggcagccccaccttcccagtgac agaggcttagaagagctgcctggccccaaaggctctgtcactctgagtgatctgccgggc ttcttaggtgatctggcctcggaggaagacagtatcgaaaaagataaggaggaagccgca atatctaaagagctttctgagatcaccccagcagaggcggagcctgtggttcctcgaggg ggctttgactctcccttctacggagacagtctcccgggctctcagcggaagacacactca gctgcctctgggatgcagggctccattgcgaaccccgagcctctacactcctccctggac aagcttgggcccgacacaccaaagcaagcctttactcccatagacctgccctgtggcgga gctgacaccagccctgcaggggacagggccccccagacttccctggcaaccagcattctc actcccagcccttgcaaaattccacctcaacggggagtggattttggaagtgggcagcct cccccatatgatcatctctttgaggtggccttgccaaagactgcctgtcactttgtcagc aagaagacggaggagctgttaaagaaagcaaaaggaagcaccgaggaagactccgcgccc tctacctcccccatggaagtactggatagactgatacagcagggagcagacgcacacagc aaggagcttagcaagttgtccttacccagcaagtctgtcgactggacccactttggaggc tctcctccctcagatgagatccgcaccctccgagaccagttgcttttactgcacaaccag ttactctatgagcgctttaagaggcagcagcacgctctccggaacagacggctcctccga aaggtgatcagggcagcagccctggaggagcacaatgctgctatgaaagatcagctgaag ttacaagaaaaagacatccaaatgtggaaggtgagtctgcagaaagaacaagccaggtac agtcagctgcaggagcagcgtgacactgtggtgacccagctccacagccagatcagacag ctgcagcatgaccgagaagaattctacaaccagagccaggaactccagacaaagctggag gactgcaggagcatgattgcggagctgcgggtggagctgaagaaggccaacagcaaggtg tgccacaccgagcttctgctcagtcaggtctctcagaagctctccaacagtgagtcggtg cagcagcagatggagttcttgaacaggcagctgttggtgctcggggaggtcaacgagctg tatttggaacagctgcagaacaagcactcggacactaccaaggaagtggaaatgatgaaa gccgcgtaccggaaagaactagaaaaaaacagaagccacgttctccagcagaatcagagg ctggatacttctcagaaacgcatttcggaactggagtctcatctggccaagaaagaccac ctcctcctggagcagaagaagtacctggaggatgtcaaggcccaggctagaggacagctg caggctgcggagagcaggtatgaggctcagaaaaggatcacacaggtgttcgagttggag atcttagacttgtatggcaggttggagaaagacggcctcctgcaaaaactcgaagaggaa aaaccagaggcagcagaagctgcagaagaaaggcttgactgttgttatgatggctgctca gatcccatgaaagggcacaaggaagaggcatctgggcacaatggtgagaccaagacccct gggcctggcagcatgcgggggagcagtggaggccgaggagctggaggcggtggcagcagc agcagcagcagtgagctttccaccccagagaaacccccaagccagagggcgggcccattc agcagtcggagggaagccactgtgggtgagcccaccaccagcatcccaactgtcggttca ctgcccagttcaaaaagctttctgggcatgaaggcccgagagttgtttcgaaacaagagt gagagccagtgtgatgaggacggcatgagcatctgcagcctccccgagagcctaaagaca gacctgggcaaagactcgggtgtggaagccaagacttccctgaacctagacggcccgcat ccttctccccccagcctggacagtgtcggacagcttcgtatcatggactacaatgaggct cgtcacgaacacagctaa

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