Heterocephalus glaber (naked mole-rat): 101708667
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Entry
101708667 CDS
T02812
Symbol
Idh2
Name
(RefSeq) isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00020
Citrate cycle (TCA cycle)
hgl00480
Glutathione metabolism
hgl01100
Metabolic pathways
hgl01200
Carbon metabolism
hgl01210
2-Oxocarboxylic acid metabolism
hgl01230
Biosynthesis of amino acids
hgl04146
Peroxisome
hgl05230
Central carbon metabolism in cancer
Module
hgl_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hgl_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
101708667 (Idh2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101708667 (Idh2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
101708667 (Idh2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101708667 (Idh2)
Enzymes [BR:
hgl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
101708667 (Idh2)
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Ortholog
Paralog
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
101708667
NCBI-ProteinID:
XP_004852838
UniProt:
A0AAX6PJX3
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Position
Un
AA seq
410 aa
AA seq
DB search
MDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPHRDQTNDQVTIDSALATQKYSVAVK
CATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKAITIGR
HAHGDQYKATDFVVDRAGTFKMVFSPKDGSGAKEWEVYNFPSGGVGMGMYNTDESISGFA
HSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKHKIWYEHRLIDD
MVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVT
RHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFTQMLEKVCVETVEGGAMT
KDLAGCIHGLSNGCQVTWAAFEGPDASGVSLLQREAERALPEHHRLSGHH
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atggatggtgacgagatgacccgcatcatctggcagttcatcaaggagaagctcatcctg
ccccatgtggatgtccagctcaagtacttcgacctcgggctcccacatcgtgaccaaacc
aatgaccaggtcaccatcgactctgcgctggccacccagaaatacagtgtggccgtcaag
tgtgccaccatcacccccgacgaggcccgtgtggaagagttcaagctgaagaagatgtgg
aagagtcccaatgggaccatccgaaacatcctcgggggcacggtcttccgagagcccatc
atctgcaaaaacatcccacgcctcgtccccggctggaccaaggccatcaccatcggcagg
cacgcacacggtgaccagtataaggccactgactttgtcgtggaccgtgctggcacgttc
aagatggtcttcagcccaaaggatggcagcggggccaaggaatgggaggtgtacaacttc
ccgtcgggtggcgtgggcatgggcatgtacaacaccgatgagtctatctcaggtttcgca
cacagctgcttccagtacgccatccagaagaagtggccgctgtacatgagcaccaagaac
accattctgaaggcctatgatgggcgcttcaaggacatcttccaggagatcttcgacaag
cactacaagacggactttgacaagcataagatctggtacgagcaccggctcatcgatgac
atggtggcccaggtcctcaagtcctctggtggcttcgtgtgggcctgcaagaactatgac
ggagacgtgcagtcggacatcctggctcagggctttggctcccttggcttgatgacgtct
gtgctggtctgcccagatgggaagaccatcgaggcagaggctgctcacgggaccgtcact
cgccactatcgagagcaccagaagggccggcctaccagcaccaaccccattgccagcatc
tttgcgtggacacgtggcctggagcaccgtgggaagctggacgggaaccaggacctcatc
aggttcacacagatgctggagaaggtgtgcgtggagactgtggagggtggagccatgacc
aaggacctggcaggctgtatccacggcctgagcaatgggtgccaggtgacttgggcagcc
ttcgaaggccccgatgcgagtggtgtctccctcctccagcgtgaagctgaacgagcactt
cctgaacaccacagactttctggacaccattaa
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