Heterocephalus glaber (naked mole-rat): 101709077
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Entry
101709077 CDS
T02812
Symbol
Fgfr2
Name
(RefSeq) fibroblast growth factor receptor 2
KO
K05093
fibroblast growth factor receptor 2 [EC:
2.7.10.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl01521
EGFR tyrosine kinase inhibitor resistance
hgl04010
MAPK signaling pathway
hgl04014
Ras signaling pathway
hgl04015
Rap1 signaling pathway
hgl04020
Calcium signaling pathway
hgl04144
Endocytosis
hgl04151
PI3K-Akt signaling pathway
hgl04550
Signaling pathways regulating pluripotency of stem cells
hgl04810
Regulation of actin cytoskeleton
hgl05200
Pathways in cancer
hgl05215
Prostate cancer
hgl05226
Gastric cancer
hgl05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101709077 (Fgfr2)
04014 Ras signaling pathway
101709077 (Fgfr2)
04015 Rap1 signaling pathway
101709077 (Fgfr2)
04020 Calcium signaling pathway
101709077 (Fgfr2)
04151 PI3K-Akt signaling pathway
101709077 (Fgfr2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101709077 (Fgfr2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101709077 (Fgfr2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101709077 (Fgfr2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101709077 (Fgfr2)
05230 Central carbon metabolism in cancer
101709077 (Fgfr2)
09162 Cancer: specific types
05226 Gastric cancer
101709077 (Fgfr2)
05215 Prostate cancer
101709077 (Fgfr2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101709077 (Fgfr2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101709077 (Fgfr2)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hgl04090
]
101709077 (Fgfr2)
00536 Glycosaminoglycan binding proteins [BR:
hgl00536
]
101709077 (Fgfr2)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101709077 (Fgfr2)
Protein kinases [BR:
hgl01001
]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
101709077 (Fgfr2)
CD molecules [BR:
hgl04090
]
Proteins
101709077 (Fgfr2)
Glycosaminoglycan binding proteins [BR:
hgl00536
]
Heparan sulfate / Heparin
Growth factors/receptors
101709077 (Fgfr2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
I-set
Ig_3
ig
Ig_2
V-set
Ig_5
ABC1
C2-set_2
FAM176
V-set_CD47
Terpene_synth_C
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
101709077
NCBI-ProteinID:
XP_004838858
UniProt:
A0AAX6NX41
LinkDB
All DBs
Position
Un
AA seq
841 aa
AA seq
DB search
MGLMSTWRYGRGPGIGTVTMVSWGHFISLVVITMATLSLARPSFNLVEDTTLEPEEPPTK
YQISQPEVYVAAPGESLELRCLLKDAALISWTKDGVHLGPNNRTVLIGEYLQIKGATPRD
SGLYACTASRTVDSETWYFMVNITDAISSGDDEDDTDGSEDFVSENSNNKRAPYWTNTEK
MEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESV
VPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVY
SDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKKQAPVREKEIPSSPDYLEIAIYCIGVFLITCMVVIVIVCRM
KTTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTVDTPML
AGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR
PPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVM
KIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI
LTLTTNEEYLDLSQPLEQYSPSSPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVK
T
NT seq
2526 nt
NT seq
+upstream
nt +downstream
nt
atgggattaatgtccacatggagatatggaagaggaccggggattggtaccgtaaccatg
gtcagctggggtcacttcatcagcctggttgtgatcaccatggcaaccttgtccctggcc
cggccctccttcaatttagttgaggataccacattagagccggaagagccaccaaccaaa
taccaaatctctcaaccagaagtttacgtggctgcgccaggggagtcgctagaattgcgc
tgcctgttgaaagatgccgccctgatcagttggactaaggatggggtacacttggggccc
aacaataggacagtgcttattggggagtacttgcagataaaaggcgccacacctagagac
tccggcctctatgcttgtactgcctctaggactgtagacagtgaaacttggtacttcatg
gtgaatatcacagatgccatctcatccggagatgatgaagatgacacggatggctctgaa
gattttgtcagtgagaacagtaacaacaagagagcaccatactggaccaacacagaaaag
atggaaaagcggctacatgctgtccccgcggccaacactgtcaaattccgctgtccagct
ggggggaatccaacgccgacgatgaggtggctgaaaaacgggaaagaatttaagcaggaa
catcgtattggaggctataaggtacgaaaccagcactggagccttattatggaaagtgtg
gtcccatctgacaaaggcaattatacctgtgtggtggagaatgaatacggctccatcaat
cacacatatcacctcgatgttgttgagcgatcgccacaccggcccatcctccaagctgga
ctgccagcaaatgcctccacagtcgtcggaggggacgtggaatttgtctgcaaagtttat
agcgacgctcagccccacatccagtggatcaagcatgtagaaaagaatggtagcaaatac
gggcctgatgggctgccctacctcaaggttctgaagcactcggggataaatagttccaat
gcagaagtgctggctctattcaatgtgactgaggcggatgctggggagtatatatgtaag
gtctccaattatatagggcaggccaaccagtctgcctggctcactgtcctgcccaaaaag
caagcgcccgtaagagaaaaggagattccatcttccccagattacctggaaatagccatt
tactgcataggggtcttcttaatcacctgtatggtggtgatagtcatcgtgtgccgaatg
aagactacaaccaagaagccagacttcagcagccagccggctgtgcacaagctgaccaag
cgcatccccctgcggagacaggtaacagtttctgctgagtccagctcctccatgaactcc
aacaccccactggtgaggatcacaacacgtctctcctcaacagtggacaccccaatgctg
gctggggtctctgaatatgaactgccagaggatccaaagtgggagttccccagagataag
ctgacgctaggaaaaccccttggggaaggttgctttggacaagtggtcatggctgaagca
gtgggaatcgacaaagacaaacccaaggaggcggtcactgtggcagtgaagatgttgaaa
gacgatgctacagagaaagatctttctgatctggtgtcagagatggagatgatgaagatg
attggaaaacataaaaatatcatcaatcttctcggagcctgcacacaggatgggcccctc
tatgtcatagttgaatatgcctccaaaggcaaccttcgggaatatctccgggcccggagg
cctccaggcatggaatactcctatgacattaaccgtgttcctgaggaacaaatgactttc
aaggacttggtgtcatgcacctaccagctggccagaggcatggagtacttggcttcccaa
aaatgtattcatcgagatttagcagccagaaatgttttggtaacagaaaacaatgtgatg
aaaatagcagactttggactggccagagatatcaacaatatagattattacaaaaagaca
acaaatgggcgacttccagtcaagtggatggctcccgaagcccttttcgatagagtgtac
acccatcagagtgatgtctggtcctttggggtgttaatgtgggagatcttcactttaggg
ggctcaccttacccagggattcctgtggaggaactttttaagctgctaaaggaaggacac
aggatggacaagccagccaactgtaccaatgagctgtacatgatgatgagggattgctgg
catgcagtgccctcacagagaccaacgttcaagcagttggtagaagacttggaccgaatt
cttactctcacaaccaatgaggaatacttggacctcagtcagcctctggaacagtactca
cctagttcccctgacacaaggagctcttgttcttcaggagatgactctgtgttttctccg
gaccccatgccttacgaaccctgcctgcctcagtatccacatataaacggcagtgttaaa
acctga
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