Heterocephalus glaber (naked mole-rat): 101709723 Help Entry 101709723         CDS       T02812                                  Symbol Itga4 Name (RefSeq) integrin subunit alpha 4   KO K06483   integrin alpha 4 Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl04151   PI3K-Akt signaling pathway hgl04510   Focal adhesion hgl04512   ECM-receptor interaction hgl04514   Cell adhesion molecule (CAM) interaction hgl04517   IgSF CAM signaling hgl04518   Integrin signaling hgl04640   Hematopoietic cell lineage hgl04670   Leukocyte transendothelial migration hgl04672   Intestinal immune network for IgA production hgl04810   Regulation of actin cytoskeleton hgl04820   Cytoskeleton in muscle cells hgl05135   Yersinia infection hgl05140   Leishmaniasis hgl05165   Human papillomavirus infection hgl05410   Hypertrophic cardiomyopathy hgl05412   Arrhythmogenic right ventricular cardiomyopathy hgl05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     101709723 (Itga4)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     101709723 (Itga4)    04514 Cell adhesion molecule (CAM) interaction     101709723 (Itga4)    04517 IgSF CAM signaling     101709723 (Itga4)    04518 Integrin signaling     101709723 (Itga4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     101709723 (Itga4)   09142 Cell motility    04820 Cytoskeleton in muscle cells     101709723 (Itga4)    04810 Regulation of actin cytoskeleton     101709723 (Itga4)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101709723 (Itga4)    04670 Leukocyte transendothelial migration     101709723 (Itga4)    04672 Intestinal immune network for IgA production     101709723 (Itga4)  09160 Human Diseases   09172 Infectious disease: viral    05165 Human papillomavirus infection     101709723 (Itga4)   09171 Infectious disease: bacterial    05135 Yersinia infection     101709723 (Itga4)   09174 Infectious disease: parasitic    05140 Leishmaniasis     101709723 (Itga4)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     101709723 (Itga4)    05412 Arrhythmogenic right ventricular cardiomyopathy     101709723 (Itga4)    05414 Dilated cardiomyopathy     101709723 (Itga4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hgl04147]     101709723 (Itga4)    04515 Cell adhesion molecules [BR:hgl04515]     101709723 (Itga4)    04090 CD molecules [BR:hgl04090]     101709723 (Itga4) Exosome [BR:hgl04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    101709723 (Itga4)   Exosomal proteins of other cancer cells    101709723 (Itga4) Cell adhesion molecules [BR:hgl04515]  Integrins   Integrin alpha subunits    101709723 (Itga4) CD molecules [BR:hgl04090]  Proteins   101709723 (Itga4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_A_Ig_1 Integrin_A_Ig_2 Integrin_A_Ig_3 FG-GAP FG-GAP_3 CATSPERG_C Integrin_alpha Motif Other DBs NCBI-GeneID:  101709723 NCBI-ProteinID:  XP_004868219 UniProt:  A0AAX6Q8X1 LinkDB All DBs Position Un AA seq 1035 aa AA seqDB search MAAAAGRGAGPRGAAVRGAVLLLLLLCLRVPGAHPYNVDAESALLFRGAPGTLFGYSVVL HSHGPDRWLVVGAPTATWLANASVLSPGAIYKCRIGKNPSRTCEQLQLGSPTGEPCGKTC LEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYVRHENKLPTGVCYGMPSDLRTELSK RMAPCYQDYVRKFGENFASCQAGISSFFTEDLIVMGAPGSSYWTGSLFVYNITTNKYKAF VDKHNQVKFGSYLGYSVGAGHFRSPHTTEVVGGAPQHEQIGKAYVFSIDAKELNILYEMK GKKLGSYFGASICAVDLNADGFSDLLVGAPMHSTVREEGRVFVFINSGVGAVMNEMETAL IGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDELRGAIYIYNGRVDGISSAFSQRI GGLQISESLSMFGQSISGQIDADNNGYIDVAVGAFRSESAVLLRTRPVVIVEASLSHPES VNRTKFDCVENGAPSVCMDLKLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPSRFYFSSN GTSDVITGSIQVSSRRANCRTHQAFMRKDVRDILTPIQIEAAYHLGHHVISKRSTEEFPP LQPILQQKKEKDMIKKVINFARFCAHENCSADLQVSAKIGFFKPYENKTYLAVGSTKTLM LNVSLFNAGDDAYETTLYIRLPTGLYFIKILDLEEKQINCEVTDNSGTVKLHCTLGYIYV DYLSRTDVSFLLDVSSLRRAEEDLNIMVLASCANEGEMDKLQDNKVIVAIPLRYEVMLAV HGFVNPASFVYGSSEDNEPETCMTEKMNFTFHVINMGISMAPNVSVEIMIPNSFLPRTDK LFNILDVQTTTGQCKFENYPRECATEQQRYAVETLKGILTFLSKTDRRVLYCMKADPYCL SFLCNFGKMESGKEASVHIQLEGRPSILEMDDTSALKFEIRATAFPEPHPRVIELNKDEN AAHVLLEGLHHQKPKRHFTIVIISSSLLLGFVVLFLISCVMWKAGFFKRQYKSILQEENR DSWSYVNSKSNDNDD NT seq 3108 nt NT seq  +upstreamnt  +downstreamnt atggctgctgcagcggggcgcggagccggaccccgcggggccgccgtccggggagccgtg ctgctactgctgctgctgtgcctgagggtccccggagcgcacccctacaacgtggacgcg gagagcgcgctgctgttccggggcgcccccggcacgctgttcggctactccgtggtgcta cacagccacggcccggaccgctggctcgtcgtgggggcgcccacggccacctggctcgcc aacgcgtcggtgctcagtcccggggccatctacaaatgtaggatcggaaagaatccaagc cggacgtgcgaacagcttcagctgggtagccctactggagaaccttgtggaaagacatgt ttggaggaaagagacaatcagtggttgggggtcacactttccagacagccaggagaaaat ggatccattgtgacttgtggacatagatggaaaaatatattttacgtgaggcatgaaaat aagctccctactggtgtttgctatgggatgccttctgatttacgaacggaactcagtaaa agaatggctccgtgttaccaagattatgtgagaaaatttggagaaaactttgcatcatgt caagctggaatatctagtttcttcacagaggatttaattgtgatgggagctccaggatcg tcttattggactggctctctttttgtctacaatataactacaaataaatacaaagccttt gtagacaaacacaatcaagtaaaatttggaagttatttaggatactcagtaggagctggt cattttcggagtccacatacaacagaagtagttggaggagcccctcagcatgaacagatt ggtaaagcctatgtattcagcattgatgccaaagaactaaatatcttatatgaaatgaaa ggtaaaaagctgggctcctattttggagcttccatctgtgccgtggacctcaatgcagat ggcttctcagacctgctggtgggagcgcccatgcacagcacggtcagggaggagggcaga gtgttcgtgttcatcaactccggtgtgggagcagtaatgaatgaaatggaaacagcactc attggaagtgataaatatgctgcaagatttggggaatctatagttaatcttggtgacatt gacaatgatggctttgaagatgtcgctattggagctccacaagaagatgaattgcgaggc gccatttacatttacaatggccgagtagatggcatctcatcagccttctcccagagaata ggaggacttcaaatcagtgaatcattgagtatgtttggacagtctatatcaggacaaatt gatgcagataataatggatatatagatgtagccgtcggtgcttttcgctctgagtctgct gtgttgctaaggacaagaccagtagtaattgttgaagcatctttaagccaccctgagtct gtaaacagaacgaaatttgattgtgttgagaatggagcgccctctgtgtgcatggatcta aagctttgtttctcatacaaaggcaaagaggttccgggttacattgttttgttttataac atgagtctggatgtgaacagaaaggcagagtctccatcaaggttttacttttcctctaat ggaacttctgatgtcatcacaggaagcatacaagtatcaagcagaagggccaactgtagg acacatcaagcatttatgaggaaagatgtgcgggacatcctcaccccaatccagattgaa gctgcttaccaccttgggcaccatgtcatcagcaaacgcagcacagaggaattcccgccc ctgcagccaatccttcagcagaagaaagaaaaagacatgattaaaaaagtgataaatttt gcaaggttttgtgcccatgaaaattgttctgctgatttacaggtttctgcaaaaattgga tttttcaagccatatgaaaataaaacctatcttgctgttggaagtacgaagacattgatg ttgaacgtgtccttgtttaatgcgggagatgacgcctatgaaacaacgctgtacatcaga ctacccacgggtctttacttcattaagattttagacctggaagagaaacaaataaactgc gaagtaacagacaactctggcacagttaaactccactgcacccttggttacatatatgta gattatctctccaggacagatgtcagctttctgctggatgtgagctcactccgtagagca gaagaggacctcaacatcatggtgcttgcctcctgtgcaaatgaaggagaaatggacaag ctacaggacaacaaagtgatagtagcaatacctctgagatacgaggttatgctagcagtt catgggtttgtgaatccagcttcattcgtgtatggatcaagtgaggacaatgaacccgaa acatgcatgactgagaaaatgaatttcactttccatgttatcaacatgggcattagcatg gctccaaatgttagtgtggaaatcatgataccaaattcttttcttccccgaactgataaa ctcttcaacattttggatgtccagacgactactggacaatgcaagtttgaaaattatcca agagaatgcgcaacagagcagcagaggtatgctgtggagactttgaaaggcatcctcaca ttcttgtcaaaaaccgataggagggtattgtattgcatgaaagcagacccgtactgctta agtttcttatgcaattttgggaaaatggaaagtggaaaagaagccagtgttcatattcag ttagaaggccggccatccattctggaaatggatgacacatcggcactcaagtttgaaata agagcaacagcttttccagagccacatcccagagttatcgaactaaacaaggatgagaat gcagcacatgttctactggaaggattacatcatcaaaaacccaaacgtcatttcaccata gtgattatttcaagtagcttgctacttggatttgttgtgctttttttgatttcatgtgtt atgtggaaggctggcttctttaaaagacaatacaaatctatcctacaagaagaaaataga gatagttggagttatgtcaacagcaaaagcaatgataatgatgattga

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