Heterocephalus glaber (naked mole-rat): 101710004
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Entry
101710004 CDS
T02812
Symbol
Cbl
Name
(RefSeq) Cbl proto-oncogene
KO
K04707
E3 ubiquitin-protein ligase CBL [EC:
2.3.2.27
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04012
ErbB signaling pathway
hgl04120
Ubiquitin mediated proteolysis
hgl04144
Endocytosis
hgl04910
Insulin signaling pathway
hgl05100
Bacterial invasion of epithelial cells
hgl05200
Pathways in cancer
hgl05205
Proteoglycans in cancer
hgl05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101710004 (Cbl)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101710004 (Cbl)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101710004 (Cbl)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101710004 (Cbl)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101710004 (Cbl)
05205 Proteoglycans in cancer
101710004 (Cbl)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
101710004 (Cbl)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
101710004 (Cbl)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hgl04131
]
101710004 (Cbl)
04121 Ubiquitin system [BR:
hgl04121
]
101710004 (Cbl)
Enzymes [BR:
hgl01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
101710004 (Cbl)
Membrane trafficking [BR:
hgl04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
101710004 (Cbl)
Ubiquitin system [BR:
hgl04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
CBL proteins
101710004 (Cbl)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cbl_N
Cbl_N3
Cbl_N2
zf-C3HC4
zf-C3HC4_3
Prok-RING_4
zf-RING_2
UBA
RING_XB3-XBAT31
zf-C3HC4_2
zf-RING_UBOX
zf-RING_5
zf-rbx1
UBA_RAD5A
zf-C3HC4_4
zf-RING_4
Motif
Other DBs
NCBI-GeneID:
101710004
NCBI-ProteinID:
XP_004856850
UniProt:
A0AAX6PQ23
LinkDB
All DBs
Position
Un
AA seq
915 aa
AA seq
DB search
MAGNVKKSSGAGAGGGSGGSGAGGLIGLMKDAFQPHHHHHHLSPHPPGTVDKKMVEKCWK
LMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRIILSRYEGKMETLGENEYFRVFMEN
LMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRI
TKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEF
DIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLG
QWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHI
KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRC
EIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDSLFMMKELAGAKVERP
PSPFSMAPQASLPPVPPRLDLLQQRVSVPPSASSLGTVPKAGSASLHKDKPLPIPPTLRD
LPPPPPPERPYAVGADTRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPGA
TPSPSDPWTGRELTNRHSLPFSLPSQMEPRADVARLGSTFSLDTSMNTSNSPLAGPECEH
PKIKPSSSANAIYSLAARPLPVPKLPPGERGESEEDTEYMTPSSRPVGLQKPELKRPSET
AQSSRVGDCDQQIDSCTYEAMYNIQSQAPSVTENSTFGEGNLAVAHPNTGPEELENDDDG
YDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPSTNFTEGSQVPERPPKPFPRRINS
ERKAGSCQQSGGTAVASPAVTPSPQLSSEIENLMSQGYSYQDIQKALVIAHNNIEMAKNI
LREFVSISSPAHVAT
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
atggctggcaacgtgaaaaagagctccggcgcgggagccggcggcggttccgggggctcg
ggcgcgggcggcctgatcgggctcatgaaggacgccttccagccgcaccaccaccaccac
cacctcagcccgcacccgccgggcaccgtggacaagaagatggtggagaagtgctggaag
ctcatggacaaggtggtgcggttgtgtcagaatccaaagctggcactaaagaatagtcca
ccttatattttagacctgctgcctgacacctaccagcatctccgtattatcttgtcaaga
tatgaggggaagatggagacgcttggagaaaatgaatattttagggtgttcatggaaaat
ttgatgaagaaaactaaacagaccataagtcttttcaaagagggaaaagaaagaatgtat
gaagagaattctcagcctaggcgaaacctaaccaaactgtccctgatcttcagccacatg
ctggcagagctgaaaggcatctttccaagtggactctttcaaggagacacatttaggatc
accaaagcagatgctgcagagttttggagaaaagcttttggagaaaagacaatagtccct
tggaagagctttcgacaggccctacatgaagtgcatcctatcagttctgggctggaggct
atggctctgaaatctaccattgatctgacttgtaatgattatatttcagtttttgaattt
gacatctttacacgactctttcagccctggtcctctttgctcaggaattggaacagcctt
gctgtaacacatcctggttacatggcttttctgacatatgatgaagtaaaagctcggctc
cagaaattcattcacaaacctggcagttacatcttccggctgagctgtactcgtctgggt
cagtgggctattgggtatgttactgctgatgggaacattctgcagacaatccctcacaat
aaacctctcttccaagcactgattgatggcttcagggaaggcttttatttatttcctgat
ggacgaaatcagaatcctgacctgacaggcctgtgtgaaccaactccccaagaccacatc
aaagtgacccaggaacagtatgaattgtactgtgagatgggatccacgttccaactgtgt
aaaatatgtgctgaaaatgataaggatgtaaagattgagccctgtggacatctcatgtgc
acatcctgtctgacatcctggcaggaatcagaaggtcaaggctgtcctttctgccgatgt
gaaatcaaaggtacagagcccattgtggtagatccatttgaccctcgaggaagtggcagc
ttattgaggcaaggagcagagggagctccctcaccaaattatgatgatgacgatgatgaa
cgagctgatgattctctcttcatgatgaaggaattggctggtgccaaggtggaacggccc
ccttctccattctccatggccccacaagcttcccttcccccagtgccaccacggcttgac
cttctgcaacagcgagtgtctgttcctccaagtgcttctagtctaggaactgtccccaag
gctggttctgcctcccttcataaggacaagccattgccaatacctcctacacttcgagat
cttccaccaccaccccctccagagcggccatatgctgttggagcagatacccgacctcag
agacgccccctgccttgtacaccaggcgattgtccatccagggataaactgccccctgta
ccctctagccgtcttggggactcatggttgccccgcccaatccccaaagtaccaggagct
actccaagccccagtgacccctggaccggaagagaattaaccaaccggcactcacttcca
ttttcattgccttcacaaatggagccaagagcagatgtggccaggcttggaagcacattc
agtctggatacttccatgaatacaagtaacagtccattagcaggtccagagtgtgagcac
cccaaaatcaaaccttcctcatctgccaatgctatttattctctggctgccagacccctt
ccagtgccaaaactgccacctggagaacggggtgagagtgaggaggacacagagtatatg
actccctcatctaggcctgtagggcttcaaaagccagagctaaaacggccttcagagaca
gcccagagttctcgagtgggtgattgtgaccagcagattgatagttgcacatatgaagca
atgtataatattcagtcccaggcgccatctgtcaccgagaacagcacctttggtgaaggg
aatttggctgtagcccaccccaacactggccctgaggaattggaaaatgatgatgatggc
tatgatgtccctaagccaccggtaccagctgtcctagcccgccgaactctctcagacatc
tccaatgctagctcatcctttggctggttgtctctggatggcgatccctcaacaaacttt
actgagggttctcaagttcctgagcggcctccaaaaccattccctcggagaatcaattct
gaacggaaagcaggtagctgtcagcaaagtggtggtactgctgtggcctcccctgctgtc
accccatcaccacagctctccagtgagattgagaacctcatgagccagggctactcctat
caggacattcagaaagctttggtcattgcccacaacaacattgaaatggccaaaaacatc
ctccgggaatttgtttctatttcatcccctgctcatgttgccacctag
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