KEGG   Heterocephalus glaber (naked mole-rat): 101710109
Entry
101710109         CDS       T02812                                 
Symbol
Rhoa
Name
(RefSeq) ras homolog family member A
  KO
K04513  Ras homolog gene family, member A
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04014  Ras signaling pathway
hgl04015  Rap1 signaling pathway
hgl04022  cGMP-PKG signaling pathway
hgl04024  cAMP signaling pathway
hgl04062  Chemokine signaling pathway
hgl04071  Sphingolipid signaling pathway
hgl04072  Phospholipase D signaling pathway
hgl04081  Hormone signaling
hgl04144  Endocytosis
hgl04150  mTOR signaling pathway
hgl04270  Vascular smooth muscle contraction
hgl04310  Wnt signaling pathway
hgl04350  TGF-beta signaling pathway
hgl04360  Axon guidance
hgl04510  Focal adhesion
hgl04517  IgSF CAM signaling
hgl04519  Cadherin signaling
hgl04520  Adherens junction
hgl04530  Tight junction
hgl04611  Platelet activation
hgl04621  NOD-like receptor signaling pathway
hgl04625  C-type lectin receptor signaling pathway
hgl04660  T cell receptor signaling pathway
hgl04670  Leukocyte transendothelial migration
hgl04722  Neurotrophin signaling pathway
hgl04810  Regulation of actin cytoskeleton
hgl04921  Oxytocin signaling pathway
hgl04928  Parathyroid hormone synthesis, secretion and action
hgl04972  Pancreatic secretion
hgl05100  Bacterial invasion of epithelial cells
hgl05132  Salmonella infection
hgl05133  Pertussis
hgl05135  Yersinia infection
hgl05152  Tuberculosis
hgl05163  Human cytomegalovirus infection
hgl05200  Pathways in cancer
hgl05203  Viral carcinogenesis
hgl05205  Proteoglycans in cancer
hgl05206  MicroRNAs in cancer
hgl05210  Colorectal cancer
hgl05417  Lipid and atherosclerosis
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    101710109 (Rhoa)
   04015 Rap1 signaling pathway
    101710109 (Rhoa)
   04310 Wnt signaling pathway
    101710109 (Rhoa)
   04350 TGF-beta signaling pathway
    101710109 (Rhoa)
   04072 Phospholipase D signaling pathway
    101710109 (Rhoa)
   04071 Sphingolipid signaling pathway
    101710109 (Rhoa)
   04024 cAMP signaling pathway
    101710109 (Rhoa)
   04022 cGMP-PKG signaling pathway
    101710109 (Rhoa)
   04150 mTOR signaling pathway
    101710109 (Rhoa)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    101710109 (Rhoa)
   04517 IgSF CAM signaling
    101710109 (Rhoa)
   04519 Cadherin signaling
    101710109 (Rhoa)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101710109 (Rhoa)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101710109 (Rhoa)
   04520 Adherens junction
    101710109 (Rhoa)
   04530 Tight junction
    101710109 (Rhoa)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101710109 (Rhoa)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101710109 (Rhoa)
   04621 NOD-like receptor signaling pathway
    101710109 (Rhoa)
   04625 C-type lectin receptor signaling pathway
    101710109 (Rhoa)
   04660 T cell receptor signaling pathway
    101710109 (Rhoa)
   04670 Leukocyte transendothelial migration
    101710109 (Rhoa)
   04062 Chemokine signaling pathway
    101710109 (Rhoa)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    101710109 (Rhoa)
   04928 Parathyroid hormone synthesis, secretion and action
    101710109 (Rhoa)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    101710109 (Rhoa)
  09154 Digestive system
   04972 Pancreatic secretion
    101710109 (Rhoa)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101710109 (Rhoa)
  09158 Development and regeneration
   04360 Axon guidance
    101710109 (Rhoa)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101710109 (Rhoa)
   05206 MicroRNAs in cancer
    101710109 (Rhoa)
   05205 Proteoglycans in cancer
    101710109 (Rhoa)
   05203 Viral carcinogenesis
    101710109 (Rhoa)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101710109 (Rhoa)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101710109 (Rhoa)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101710109 (Rhoa)
   05135 Yersinia infection
    101710109 (Rhoa)
   05133 Pertussis
    101710109 (Rhoa)
   05152 Tuberculosis
    101710109 (Rhoa)
   05100 Bacterial invasion of epithelial cells
    101710109 (Rhoa)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101710109 (Rhoa)
   05418 Fluid shear stress and atherosclerosis
    101710109 (Rhoa)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hgl04131]
    101710109 (Rhoa)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hgl04147]
    101710109 (Rhoa)
   04031 GTP-binding proteins [BR:hgl04031]
    101710109 (Rhoa)
Membrane trafficking [BR:hgl04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    101710109 (Rhoa)
Exosome [BR:hgl04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101710109 (Rhoa)
  Exosomal proteins of other body fluids (saliva and urine)
   101710109 (Rhoa)
  Exosomal proteins of colorectal cancer cells
   101710109 (Rhoa)
  Exosomal proteins of bladder cancer cells
   101710109 (Rhoa)
GTP-binding proteins [BR:hgl04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    101710109 (Rhoa)
SSDB
Motif
Pfam: Ras Roc GTP_EFTU Arf VASP_tetra
Other DBs
NCBI-GeneID: 101710109
NCBI-ProteinID: XP_012925513
UniProt: G5BZW2
LinkDB
Position
Un
AA seq 170 aa
VFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMC
FSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEE
GRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLVL
NT seq 513 nt   +upstreamnt  +downstreamnt
gtttttagcaaggaccagttcccagaagtatatgtgcccacagtgtttgagaactatgtg
gcagatattgaagtggatggaaagcaggtagagttggctttatgggacacagctggacag
gaagattatgatcgcctgaggcctctctcctacccagacacggatgttatactgatgtgt
ttctccattgacagccctgatagtttagaaaacatcccagaaaaatggaccccagaagta
aagcatttctgtcccaatgtacccattatcctggttggaaacaagaaggatcttcggaac
gatgagcacacaagacgggagttagccaagatgaagcaggagccagtaaaacctgaagaa
ggcagagatatggcaaacaggattggcgcctttgggtacatggaatgttcagcgaagacc
aaagatggagtgagggaggtttttgaaatggccacaagagctgctctgcaagccaggcgt
gggaagaaaaaatctgggtgccttgtcttgtga

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