Heterocephalus glaber (naked mole-rat): 101711105
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Entry
101711105 CDS
T02812
Symbol
Slc8a1
Name
(RefSeq) solute carrier family 8 member A1
KO
K05849
solute carrier family 8 (sodium/calcium exchanger)
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04020
Calcium signaling pathway
hgl04022
cGMP-PKG signaling pathway
hgl04260
Cardiac muscle contraction
hgl04261
Adrenergic signaling in cardiomyocytes
hgl04371
Apelin signaling pathway
hgl04740
Olfactory transduction
hgl04961
Endocrine and other factor-regulated calcium reabsorption
hgl04974
Protein digestion and absorption
hgl04978
Mineral absorption
hgl05410
Hypertrophic cardiomyopathy
hgl05412
Arrhythmogenic right ventricular cardiomyopathy
hgl05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
101711105 (Slc8a1)
04020 Calcium signaling pathway
101711105 (Slc8a1)
04022 cGMP-PKG signaling pathway
101711105 (Slc8a1)
09150 Organismal Systems
09153 Circulatory system
04260 Cardiac muscle contraction
101711105 (Slc8a1)
04261 Adrenergic signaling in cardiomyocytes
101711105 (Slc8a1)
09154 Digestive system
04974 Protein digestion and absorption
101711105 (Slc8a1)
04978 Mineral absorption
101711105 (Slc8a1)
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption
101711105 (Slc8a1)
09157 Sensory system
04740 Olfactory transduction
101711105 (Slc8a1)
09160 Human Diseases
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
101711105 (Slc8a1)
05412 Arrhythmogenic right ventricular cardiomyopathy
101711105 (Slc8a1)
05414 Dilated cardiomyopathy
101711105 (Slc8a1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hgl02000
]
101711105 (Slc8a1)
00536 Glycosaminoglycan binding proteins [BR:
hgl00536
]
101711105 (Slc8a1)
Transporters [BR:
hgl02000
]
Solute carrier family (SLC)
SLC8: Na+/Ca2+ exchanger
101711105 (Slc8a1)
Glycosaminoglycan binding proteins [BR:
hgl00536
]
Heparan sulfate / Heparin
Others
101711105 (Slc8a1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Calx-beta
Na_Ca_ex_C
Na_Ca_ex
DnaG_DnaB_bind
Motif
Other DBs
NCBI-GeneID:
101711105
NCBI-ProteinID:
XP_012925649
UniProt:
A0AAX6QSD5
LinkDB
All DBs
Position
Un
AA seq
970 aa
AA seq
DB search
MLRLNLSPTFSLGFHLLAMMALLISHVDHITAETEMVEEGNETGECTGSYYCKKGVILPI
WEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETT
KTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIII
ALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFP
ICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVENF
LDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAF
YRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVADNDPVSKIFFEQGTYQCLENCG
TVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGETQKEIRVGIIDDD
IFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPCTATVTIFDDDHAGIFTFE
EPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIV
KTVSVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGEYLYGQPVFRK
VHAREHPIPSTVITIADEYDDKQPLTSKEEEERRIAELGRPILGEHTKLEVIIEESYEFK
STVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTV
FWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVAL
GTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVS
PGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSS
LEAYCHIKGF
NT seq
2913 nt
NT seq
+upstream
nt +downstream
nt
atgctgcgattaaatctctcacccacgttttcactggggtttcatctgctagctatgatg
gctctcctaatttcccatgtggatcatataactgctgagacagaaatggtggaagaagga
aatgaaaccggtgaatgtactggctcctattactgtaagaaaggggtgattttgcccatt
tgggagccccaagacccttcttttggggacaaaattgctagagcaactgtgtattttgtg
gccatggtctacatgtttcttggcgtctctatcatagctgacaggttcatgtcctccatc
gaagtcatcacatcgcaagaaaaagaaataaccataaagaaacccaatggagagaccacc
aagacaactgtgaggatctggaatgagaccgtgtctaacctgaccttgatggccctggga
tcctctgctcctgaaattctcctttcagtaattgaagtgtgtggccataacttcactgca
ggagaccttggtcctagcaccattgtgggaagcgctgccttcaacatgtttatcatcatt
gccctttgtgtttatgtggtccctgatggagaaacaaggaagattaagcatttgcgtgtg
ttctttgtgacagcagcctggagcatctttgcctatacctggctttatatcattttgtct
gtcatttctcctggagttgtggaggtctgggaaggtttgcttactttctttttcttcccc
atctgtgttgtgttcgcatgggtagcagacaggagacttctgttttacaagtatgtctac
aagcgctatcgggctggcaaacagaggggaatgattatagaacatgaaggtgacaggcca
tcttccaaaactgaaatcgaaatggatgggaaagtagtcaactctcacgttgaaaatttc
ttagatggtgctctggttctggaggttgatgagagggaccaagatgatgaagaagctagg
agagaaatggcaaggattctgaaggaacttaagcagaagcacccagagaaggaaatagag
caattaatagaattagctaactaccaagtcttaagtcagcagcaaaagagtagagcattt
taccgaattcaagctactcgcctgatgactggcgctggcaatattttaaagaggcatgca
gctgaccaagctaggaaggctgtcagtatgcatgaggtcaacacagaagtggctgacaat
gaccccgttagtaagatcttctttgagcaagggacataccagtgtctggagaactgtggt
acagtggccctgaccattatccgtagaggtggcgatctgaccaacactgtgtttgttgac
ttcagaacagaggatggcacagccaatgccgggtctgattatgaatttactgaaggaact
gtggtctttaaacctggtgagacacaaaaggaaatcagagttggcatcattgatgatgat
atctttgaggaggatgaaaatttccttgtgcatctgagcaatgtcaaagtatcttctgag
gcttcagaagatggcatactggaagccaaccatgtttctacccttgcttgccttggatca
ccctgcactgccactgttactatttttgatgatgaccatgcaggcatctttacttttgag
gaacccgtgacccacgtgagtgaaagcattggcatcatggaggtgaaagtattgagaaca
tctggagctcgaggaaatgttattgttccctataaaaccatcgaaggaactgccagaggt
ggaggggaggactttgaggacacctgtggagagctcgaattccagaacgatgaaattgtc
aaaacagtatcagtcaaggtaattgatgatgaggagtatgagaaaaacaagaccttcttc
cttgagatcggagagccccgcctggtggagatgagtgagaagaaagccctgctattgaat
gagcttggtggcttcacaataacaggagaatatctgtatggccaacctgtcttcaggaaa
gttcatgctagagaacatccgattccctctactgtaatcaccattgcagatgaatatgat
gacaaacagccgctaaccagcaaagaggaagaggagaggcgcattgcagaactggggcgc
cccatcctgggagaacacaccaagctggaagtgatcattgaggagtcctatgaattcaag
agtacggtggacaaactcattaagaagacaaacctggcccttgtggtgggtaccaacagc
tggagagaacagttcattgaggctatcactgtcagtgctggggaagatgatgacgacgat
gaatgtggggaggagaagttgccctcctgttttgattatgtgatgcactttctgactgtc
ttctggaaggtcctgtttgccttcgtaccccctacagaatactggaatggctgggcatgt
ttcattgtctccattctcatgattggcctactgacagctttcattggagacctggcttcc
cactttggctgcaccattggcctaaaagactccgtgactgctgttgtgttcgtcgcactg
ggaacttcagtgccagacacatttgccagcaaagtggcagccacccaggaccagtatgca
gacgcatccataggtaacgtcacaggcagcaacgcggtgaacgtcttcctggggatcggc
gtggcctggtccattgctgccatctaccatgcagccaatggggaacagttcaaagtgtcc
cctggcacattagctttctctgtcactctcttcaccattttcgctttcatcaatgtgggg
gtgctgctgtatcggcggaggccagaaatcggaggtgagctgggtgggccccggactgcc
aagctcctcacatcctccctctttgtgctcctatggctcttgtacattttcttctcttcc
ctggaggcctactgccacataaaaggcttctaa
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