Heterocephalus glaber (naked mole-rat): 101711512 Help Entry 101711512         CDS       T02812                                  Symbol Ep300 Name (RefSeq) E1A binding protein p300   KO K04498   E1A/CREB-binding protein [EC:2.3.1.48] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl03083   Polycomb repressive complex hgl03250   Viral life cycle - HIV-1 hgl04024   cAMP signaling pathway hgl04066   HIF-1 signaling pathway hgl04068   FoxO signaling pathway hgl04110   Cell cycle hgl04310   Wnt signaling pathway hgl04330   Notch signaling pathway hgl04350   TGF-beta signaling pathway hgl04520   Adherens junction hgl04630   JAK-STAT signaling pathway hgl04720   Long-term potentiation hgl04916   Melanogenesis hgl04919   Thyroid hormone signaling pathway hgl04922   Glucagon signaling pathway hgl04935   Growth hormone synthesis, secretion and action hgl05016   Huntington disease hgl05152   Tuberculosis hgl05161   Hepatitis B hgl05164   Influenza A hgl05165   Human papillomavirus infection hgl05166   Human T-cell leukemia virus 1 infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05200   Pathways in cancer hgl05203   Viral carcinogenesis hgl05206   MicroRNAs in cancer hgl05211   Renal cell carcinoma hgl05215   Prostate cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09120 Genetic Information Processing   09126 Chromosome    03083 Polycomb repressive complex     101711512 (Ep300)   09125 Information processing in viruses    03250 Viral life cycle - HIV-1     101711512 (Ep300)  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     101711512 (Ep300)    04330 Notch signaling pathway     101711512 (Ep300)    04350 TGF-beta signaling pathway     101711512 (Ep300)    04630 JAK-STAT signaling pathway     101711512 (Ep300)    04066 HIF-1 signaling pathway     101711512 (Ep300)    04068 FoxO signaling pathway     101711512 (Ep300)    04024 cAMP signaling pathway     101711512 (Ep300)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     101711512 (Ep300)   09144 Cellular community - eukaryotes    04520 Adherens junction     101711512 (Ep300)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     101711512 (Ep300)    04935 Growth hormone synthesis, secretion and action     101711512 (Ep300)    04919 Thyroid hormone signaling pathway     101711512 (Ep300)    04916 Melanogenesis     101711512 (Ep300)   09156 Nervous system    04720 Long-term potentiation     101711512 (Ep300)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101711512 (Ep300)    05206 MicroRNAs in cancer     101711512 (Ep300)    05203 Viral carcinogenesis     101711512 (Ep300)   09162 Cancer: specific types    05211 Renal cell carcinoma     101711512 (Ep300)    05215 Prostate cancer     101711512 (Ep300)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101711512 (Ep300)    05161 Hepatitis B     101711512 (Ep300)    05164 Influenza A     101711512 (Ep300)    05167 Kaposi sarcoma-associated herpesvirus infection     101711512 (Ep300)    05165 Human papillomavirus infection     101711512 (Ep300)   09171 Infectious disease: bacterial    05152 Tuberculosis     101711512 (Ep300)   09164 Neurodegenerative disease    05016 Huntington disease     101711512 (Ep300)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:hgl03000]     101711512 (Ep300)    03036 Chromosome and associated proteins [BR:hgl03036]     101711512 (Ep300)    03029 Mitochondrial biogenesis [BR:hgl03029]     101711512 (Ep300) Enzymes [BR:hgl01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.48  histone acetyltransferase      101711512 (Ep300) Transcription factors [BR:hgl03000]  Eukaryotic type   Other transcription factors    Pocket domain CBP     101711512 (Ep300) Chromosome and associated proteins [BR:hgl03036]  Eukaryotic type   Histone modification proteins    HATs (histone acetyltransferases)     101711512 (Ep300) Mitochondrial biogenesis [BR:hgl03029]  Mitochondrial quality control factors   Regulator of mitochondrial biogenesis    Coactivators     101711512 (Ep300) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  HAT_KAT11 KIX Creb_binding zf-TAZ RING_CBP-p300 PHD_P300 Bromodomain ZZ KIX_2 Npa1 Med15_N Motif Other DBs NCBI-GeneID:  101711512 NCBI-ProteinID:  XP_004845589 UniProt:  A0AAX6P7H3 LinkDB All DBs Position Un AA seq 2420 aa AA seqDB search MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD ISQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQNSPGLGLINS MVKSPMAQAGLTSPSMGMGTSGPNQGPTQSTTGMMSSPVNQPAMGMSPGMNAGINPGMLA AGNGQGLMPGQVMNGSIGAGRGRPNMQYSNPSMGNAGNLLTEPLQQGSPQMGGQTGLRGP QPLKMGIMNNPNPYGSPYAQNSGQQIGASGLGLQIQAKPALPNSLSPFPMDKKVVPGGGM PNMGQQPAPQVQQPGLVTPVTQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN AGDKRNQQSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLTYSGNQ MQPQPQVQAKNQQNQQSGQSPQGIRPMNSMSASPMGVNGGVGVQTPNLLSDSMLHSAINS QSPMMNENASVASLGPMPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMMP NAAGMVPVSMNPGPNMGQPQPGIASNGPLPDPAMIRGSVPNQIMPRITPQPGLNQFGPMS MPQPPIGPRQTSPLQHHGQLAQPGALNPPMGYGPRMQQPSSQSQFLSQTQFPSQGMNVTN MPLAPSSGQASVSQAQMSSSSCPVNSPVMPPGSQGSHIHCPPLPQQALHQNSPSPVPSRT PTPHHTPPSIGAQQPPTTAIPAPVPTPPAIPPRPQSQGLHPPSSQTPTPPTTQLPPQVQP PLPAAPSADQAQQQPRSQQSTAASIPTPTAPLLPPQPTTPLSQPTVSIEGQVSNPPSTSS TEVNSQTIPEKQPSQEVKMDIKMEVDHPETADAQPEDIQEAKAEECKVEPTETEERSTEL KPEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPV DPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVY KYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYH FCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICV LHHEIIWPAGFICDGCLKKTARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESG EVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQ EYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACP PSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAK ELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKN KSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLI PCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVET RWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCI QSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQEN KCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPT GQQPATPQTPQPQPTSQPQPTPPNSMPPYLPRTQTAGPVSQGKAAGQVTPPTPPQTAQPS LPGPPPAAVEMAMQIQRAAETQRQMAQVQIFQRPIQHQMPQMTPMAPMGMNPPPMTRGPS GHLEPGMGPTAMQQQPPWAQGGLPQPQQLQSGMPRPTMMSVSQHGQPLNIAPQPGLGQVG VSPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNP QPLTGQPGMAQGQPGLQPPAMPGQQGVHSSPGMQNMNPMQAGVQRAGLAQQQPQQPLQPP MGGMSPQAQPMNMNHGSMSSQFRDMLRQQQMMRQQQQQGAGPGIGPGMANHNQFQQPQGV SYPPQQQQQQRMQHHMQQIQQGNMGQMGQLPPALGAEAGASLQAYQQRLLQQQMGSPGQP NPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQP SPHHVSPQTSSPHPGLVAAQAANPMEQGHFASPDQNPMLSQLASHPGMANLHGASATDLG LSTDNSDLNSNLSQSTLDIH NT seq 7263 nt NT seq  +upstreamnt  +downstreamnt atggccgagaatgtggtggaaccggggccgccttcagccaagcggcctaaactctcgtct ccggccctctcggcgtcggccagcgacggcacagattttggctctttgttcgacctggag catgacttaccagatgaattaatcaactctacagaattgggactgaccaatggtggtgat attagtcagcttcagacaagtcttggcatggtacaagatgcagcctctaaacataaacag ctatcagaattgctacggtctgggagttcccctaacctcaatatgggggttggtggccca ggccaagttatggccagccaggcccaacagaatagtcctggattaggtctgataaacagc atggtcaaaagcccaatggcgcaggcaggattgacttctcccagcatggggatgggcact agtggaccaaatcagggtcccacgcagtccacaacaggtatgatgagcagccccgtaaat cagcccgccatgggaatgagcccagggatgaatgctggcataaaccctggaatgttggct gcaggcaatggacaggggctaatgccaggccaagtcatgaatggttcgattggagcaggc cgaggacgaccaaatatgcagtattcaaacccaagcatgggaaatgctggcaacttattg acagagccactgcagcagggctcaccccagatgggaggacagacaggactgagaggccct cagcctcttaagatgggaataatgaacaaccccaacccttatggatcaccttatgctcag aattctggacagcagattggagccagtggccttggtctccagattcaggcaaagcctgca ctaccaaatagcttatctccatttccaatggacaaaaaggtggttcctggtgggggaatg cccaacatgggccaacaacctgccccacaggtccagcagccaggcctggtgactccagtc acccaggggatgggttctggagcacacacagctgatccggagaagcgcaagctcattcag cagcagcttgttctccttctgcacgctcacaagtgccagcgccgggagcaggctaatggg gaggtgaggcagtgcaaccttcctcactgccgtacaatgaagaatgtcctgaaccacatg acgcactgccagtcaggcaagtcctgccaagtggcacattgtgcatcttctcgacaaatc atttcacactggaagaactgtacaaggcatgattgtcctgtatgtctcccgctcaaaaat gctggggataagagaaatcaacagtcgattttgactggagcaccagttgggcttggaaac cccagctctctaggggtgggtcaacagtctacccctagcctcagcactgttagtcagatt gatcccagctcaatagaaagagcctatgcagctcttggactgacctattcaggaaaccag atgcagcctcaaccccaggtgcaggcgaagaaccagcagaatcagcaatctgggcagtct ccccaaggcatccggcccatgaacagcatgagtgctagtcctatgggagtaaacggtggt gtaggggttcaaacaccgaatcttctttctgactcaatgttgcattcagccataaattct caaagcccaatgatgaatgaaaatgccagtgttgcctccctgggccctatgccaacagca gctcagccatccagtactggaattaggaaacagtggcatgaagatattactcaggatctt cgaaatcatcttgttcacaaacttgttcaagccatatttcctactccggaccctgctgca ttaaaagacagacggatggaaaacctggttgcctatgctcgcaaagtggaaggggacatg tatgaatctgcaaataatcgagcggaatactaccaccttctagctgagaagatctataag atccagaaagaattagaagaaaaacgaaggaccagactacagaaacagaacatgatgcca aatgctgcaggcatggtaccggtttctatgaatccagggcctaacatgggacagccacaa ccaggaatagcttctaatggtcctctgcctgatccagctatgatccgtggcagtgtgcca aaccagataatgcctcggataactccacaacctggtttgaatcagtttggcccgatgagt atgccccagccacccattggcccccggcaaacctctcctcttcagcaccatggacagtta gctcagcctggtgctctcaatccgcctatgggctatggccctcgcatgcagcagccttcc agccagagccagttcctctcccagactcagttcccgtcacagggaatgaatgtaacaaac atgcctttggctccatccagcggtcaagcatcagtgtctcaagcacaaatgtccagctct tcctgcccagtgaactctcctgtcatgcctccagggtctcaggggagccacattcactgt ccccctctccctcaacaagctctgcatcagaactcaccctctcccgtacctagtcggacc cccaccccccaccacactcccccaagcataggggctcagcagccaccgacaacagcaatt ccagcccctgttcccacacctcctgccataccacccaggccacagtcccagggtctacat ccaccctccagtcagacacccaccccgcctacaacacagcttcctccccaagtgcagcct ccacttcctgctgctccttcagctgaccaggcacagcagcagcctcgctcacagcagagt acagcagcctccattcccactccaacggcaccactgctgcctccacagcctacgactccg ctttcccagcctacagtgagcattgaaggacaggtatcaaaccctccatctacaagtagc acagaagtgaattctcagacaattcctgagaagcagccttcacaggaagtgaaaatggac attaaaatggaagtggatcacccagaaacagcagatgcgcagccagaggatattcaggag gctaaagcagaggaatgtaaagtggagcccacagaaacagaagagagaagtacagagtta aaacctgaaataaaagaggaggaagaccagccaagtacttctgctacccagtcttctcca gctccaggacagtcaaagaaaaaaatttttaaaccagaagaattacgacaggccctgatg ccaaccctggaggcactttaccggcaggacccagaatcccttccctttcgtcagcctgtg gaccctcagcttctaggaatccctgattatttcgatattgtgaagagccccatggacctt tctactatcaagaggaagttagacactggacagtatcaagaaccctggcaatacgtggat gacatttggcttatgttcaacaatgcctggttatataaccggaaaacatcgcgggtatac aaatactgctccaagctatctgaggtctttgaacaagaaattgatccagtcatgcaaagc cttggatattgttgtggcagaaagttggagttttctccacagacactgtgttgctatggc aaacagttatgcacaatccctcgtgatgccacttactacagttaccagaacaggtatcat ttctgtgagaagtgtttcaatgaaatccaaggggagagcgtttctttgggggatgaccct tcccagcctcaaactacaataaataaggaacagttttccaagagaaaaaatgacacactg gatcctgaattgtttgttgaatgcactgagtgtggaagaaagatgcatcagatctgtgtc cttcatcatgagatcatctggccagctggatttatctgtgatggatgcttgaagaaaact gcacgaaccaggaaagaaaataagttttctgctaaaaggttgccatctaccagacttggc acctttctggagaatcgtgtgaatgactttctgaggcgacaaaatcaccctgaatcagga gaggtcactgtcagggttgttcatgcttctgacaaaactgtggaagtcaaaccaggcatg aaagcaaggtttgtagatagtggagaaatggcagaatcctttccataccgaaccaaagct ctctttgccttcgaagaaattgatggtgttgacttgtgcttctttggcatgcacgttcaa gagtatggctctgactgccctccacccaaccagaggagagtatatatatcttacctcgat agtgttcatttcttccgtcctaagtgcttgaggactgcagtgtatcatgaaattctaatt ggatatttagaatatgtcaagaaattaggatatacaacagggcatatttgggcatgtcca ccaagtgagggggatgattatatcttccattgccatcctcctgaccagaagatacccaag cccaagcgactgcaagaatggtacaaaaagatgcttgacaaggctgtgtcagaacggatt gtacatgactacaaggatatttttaaacaagctactgaagatcgattaacaagtgcaaag gaattgccatactttgagggtgatttctggcccaatgttctggaagagagcattaaggaa ctggaacaggaggaggaagagagaaaacgagaagagaataccagcaatgaaagcactgat gtgacaaagggagacagcaaaaatgccaaaaagaagaataataagaaaaccagcaaaaat aagagcagcctgagtaggggtaacaagaagaagccaggcatgcccaatgtgtctaatgac ctctcacagaaactctacgccaccatggagaaacacaaagaggtcttctttgtgatccgc ctcattgctggccctgctgccaactctctgcctcccattgttgatccagaccctcttatc ccctgtgatctgatggatgggcgggatgcattcctcacccttgcaagggacaagcacctg gagttctcttcattgaggcgagcccagtggtccaccatgtgcatgcttgtggagctgcac acgcagagccaggaccgctttgtctacacctgcaatgagtgcaagcaccatgtggagaca cgctggcactgcactgtctgtgaggattatgacttgtgtatcacgtgctataacactaaa aaccatgaccacaagatggagaaattgggtcttggcttagatgatgagagcaacaaccaa caggctgcggccacccagagcccaggagattctcgccgcctgagcatccagcgctgcatc cagtccctggtccatgcctgtcagtgccgcaatgccaactgctccctgccctcttgccaa aagatgaaacgagttgtacagcacaccaagggctgcaaacggaaaaccaatggcgggtgc cccatctgcaagcagctgattgctctctgctgttaccatgccaagcactgccaggagaac aagtgccctgtgccattctgcctcaacatcaagcaaaagctccgccaacagcagctacag cacaggctccagcaggcccagatgctgcgcaggaggatggccagcatgcagcgcactggt gtggtggggcagcaacagggcctgccctccccaactcctgccactccaaccacaccaacg ggccaacagccagcaaccccgcagacaccccagccccagcctacctctcagccccagccc acccctcccaacagcatgccaccctacttgcccaggactcaaactgctggcccagtgtcc cagggtaaggcagcaggccaggtgacccctccaactcctcctcagactgcacagccatct cttccagggcctccacctgctgcagtagaaatggcaatgcagattcagagagcagctgag acacagcgccagatggcccaggtgcaaattttccaaaggccaatccagcaccagatgccc cagatgactcccatggcccccatgggtatgaacccacctcccatgaccagaggccccagt gggcatctagagccagggatggggccaacagcaatgcaacagcagcccccctgggcccaa ggaggactgcctcaaccccagcaactccagtctgggatgccaaggccaaccatgatgtca gtgtcccaacacgggcagcctttgaacatagctccgcagccagggttgggccaggtaggt gtgagcccactcaaaccaggcactgtgtctcaacaagccttacaaaacctccttcggact ctcaggtctcccagctctcccctacagcagcaacaggtgcttagtatccttcacgccaac cctcagctgttggctgcattcataaaacaacgggctgccaaatacgccaactctaatcca cagcctctcactggacagcctggcatggcccagggacagccagggctgcagccaccagcc atgccaggtcagcagggcgtccactccagtccaggcatgcagaacatgaatcccatgcag gcaggtgtgcagagggctggtctggcccagcagcagcctcagcagccactccagccaccc atgggagggatgagcccccaggcacagccaatgaacatgaatcatggcagcatgtcttcc cagttccgggacatgttgagacaacagcagatgatgcgacaacagcagcagcagggagca gggccaggaataggccctggaatggccaaccacaaccagttccagcaaccccagggagtt agttaccccccacagcagcagcagcagcagcggatgcagcatcacatgcagcagatacaa caagggaacatgggacagatggggcagcttcccccggccttgggagcagaggcaggagcc agtctacaggcctatcagcagcgactcctccagcagcagatggggtcccctggtcagccc aaccccatgagcccccagcagcacatgctcccaaaccaggcccagtccccgcacctccaa ggccagcagatcccaaattctctctccaatcaagtgcgttctccccagcctgtcccttct ccacggccacagtcccagcccccccactccagcccatccccaaggatgcagcctcagcct tctccacaccacgtttccccacaaaccagttccccacatcccggactggttgctgcccag gccgccaaccccatggaacaagggcattttgccagcccagaccagaatccgatgctctct cagctcgctagccatccaggcatggcaaacctccatggtgcaagtgccacggacctggga ctcagcaccgataactcagacttgaattcaaacctctcacagagtacactagacatacac tag

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