Heterocephalus glaber (naked mole-rat): 101711921 Help Entry 101711921         CDS       T02812                                  Symbol Lrp5 Name (RefSeq) LDL receptor related protein 5   KO K03068   low density lipoprotein receptor-related protein 5/6 Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl04150   mTOR signaling pathway hgl04310   Wnt signaling pathway hgl04928   Parathyroid hormone synthesis, secretion and action hgl05010   Alzheimer disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05200   Pathways in cancer hgl05224   Breast cancer hgl05225   Hepatocellular carcinoma hgl05226   Gastric cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     101711921 (Lrp5)    04150 mTOR signaling pathway     101711921 (Lrp5)  09150 Organismal Systems   09152 Endocrine system    04928 Parathyroid hormone synthesis, secretion and action     101711921 (Lrp5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101711921 (Lrp5)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     101711921 (Lrp5)    05226 Gastric cancer     101711921 (Lrp5)    05224 Breast cancer     101711921 (Lrp5)   09164 Neurodegenerative disease    05010 Alzheimer disease     101711921 (Lrp5)    05022 Pathways of neurodegeneration - multiple diseases     101711921 (Lrp5)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hgl04131]     101711921 (Lrp5) Membrane trafficking [BR:hgl04131]  Endocytosis   Clathrin-mediated endocytosis    Low-density lipoprotein receptor (LDLR) family proteins     101711921 (Lrp5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ldl_recept_b FXa_inhibition Ldl_recept_a Vgb_lyase DUF5050 SGL EGF_LRP2 EGF cEGF Insulin_TMD Motif Other DBs NCBI-GeneID:  101711921 NCBI-ProteinID:  XP_004852686 UniProt:  A0AAX6PIS3 LinkDB All DBs Position Un AA seq 1606 aa AA seqDB search MGAAPPRPPLVLLALCCSLAPAAASPLLLFANRRDVRLVDAGGVKLESTIVVSGLEDAAA VDFQFSKGAVYWTDVSEEAIKQTYLNQTGAATQNVIVSGLVSPDGLACDWVGKKLYWTDS ETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGETPRIERAGMDGSTRK IIVDSEIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSG DTLYWTDWQTRSIHACNKRTGEKRKEILSALYSPMDIQVLSQERQPFFHTQCEEDNGGCS HLCLLSPREPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVL QVEDIRHAIAIDYDPLEGHVYWTDDEVRAIRRARLDGSGAQTLVNTEINDPDGIAVDWVA RNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGENPKIECA NLDGRERHVLVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPH IFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNVAKVIGTNPCAD GNGGCSHLCFFTPRATKCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISLETNNNDV AIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPEGMAVDW MGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIV RAFMDGTNCITLVDKVGRANDLTIDYADQRLYWTDLDTNMIESSNMLGQERVVIADDLPH PFGLTQYSNYIYWTDWNLHSIERADKTSGRNRTLVQGHLDFVMDILVFHSSRQDGLNDCV HNNGQCEQLCLAIPGGHRCGCASHYTLDPSSRNCSPPSTFLLFSQKCAISRMIPDDQHSP DLILPLHGLRNVKAIDYDPLDKFIYWVDGRQNIKRAKDDGSQTFVLTSPGQSPDRQPHDL SIDIYSRTLFWTCEAANTINVHRLDGDAMGVVLRGDRDKPRAITVNAERGYLYFTNMQDR AAKIERAALDGTEREVLFTTGLIRPVALVVDNALGKLFWVDADLKRIESCDLSGANRLTL EDANIVQPVGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRIQGRVAHLTGIHAVEEVNL EEFSAHPCARDNGGCSHICIAKGDGTPRCSCPVHLVLLQNLLTCGEPPTCSPDQFACATG EIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGEADCQDRSDE ADCDAVCLPNQFRCASGQCVLIKQQCDSFPDCVDGSDELMCEITKPPSDETPAHSSAIGP VIGIILTLFIMGGLYFVCQRVVCQRYSGASGPFPHEYVSGTPHVPLNFIAPGGSQHGPFP GISCSKSVMSSVSLMGGRSGAPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPS LYNMDMFYSSNIPATTRAYRPYIIRGMAPPTTPCSTDVCDSDYSASRWKASKYYLDLNSD SDPYPPPPTPHSQYLSAEDSCPPSPVTERSYCHLFPPPPSPCTDSS NT seq 4821 nt NT seq  +upstreamnt  +downstreamnt atgggcgcggcaccgccccggccgccgctggtgctcctggccttgtgctgcagcctggcc cccgccgcggcctcgccgctcctgctgtttgccaaccgccgggacgtgcgactggtggac gctggtggagtcaagctggagtccaccatcgtggtcagcgggctggaggatgcagctgcc gtggacttccagttctccaagggtgccgtgtactggacagatgtgagcgaggaggccatc aagcagacctacctgaaccagacaggggcggctacacagaatgtcatcgtctccggcctg gtctcgcctgatggcctggcctgcgactgggttggcaaaaagctgtactggacagactca gagaccaaccgcattgaggtggccaacctcaatggcacatcccggaaggtgctcttctgg caggacctggaccagccaagggccattgccctggaccctgctcatgggtacatgtactgg acagactggggggagacgcccaggattgagcgggctgggatggacggcagcacccggaaa atcattgtggactcagaaatttactggcccaatgggctgaccattgacctggaggagcag aagctctactgggccgacgccaagctcagcttcatccatcgcgccaacctagatggatcg ttcaggcagaaagtggtagaaggcagcctgacgcaccccttcgctctgacgctgtctgga gacacgttgtactggacggactggcagacccgttccattcacgcctgtaacaagagaact ggtgagaagagaaaagagatcctcagcgccctctactcgcccatggacatccaggtgctc agccaggagcggcagcctttcttccacacacaatgtgaggaggacaatggcggctgctcc cacctatgcctgctgtccccaagggagcctttctacacctgcgcctgccccaccggcgtg cagctccaggacaatggcaggacgtgtaaggcaggggccgaggaggtgctgctgctggcc cggcgtacggacctgcggaggatctcactggacacgccagacttcacagacattgtgctt caggtggaagacatccggcacgccattgccattgactatgatccattggagggccacgtc tactggacggatgatgaggtgcgggccatccgcagggcacgtctggatggctcaggggca cagacactggtgaacactgagattaacgaccccgatggcatcgccgtggactgggtggcc cgaaacctctattggactgacacgggcaccgaccgcattgaggtgacacgcctcaatggc acctcccgcaagatcctggtgtccgaggacctggatgagccccgggctatcgtgctgcac cctgtgatgggcctcatgtactggacagactggggggagaaccccaaaatcgagtgtgcc aacctggacggacgggagcggcatgtcctggtgaacacctccctcgggtggcccaacggc ttggccctggacctgcaggagggcaagttgtactggggagacgccaagacggacaaaatt gaggtgatcaacgtggatgggacaaagaggaggaccctcctggaggacaagctcccacac atttttgggttcacactgctgggggatttcatctactggactgactggcagcggcgcagc attgagcgggtacacaaggtcaaggccagcagggatgtcatcattgatcagctgcctgac ctgatggggctcaaagccgtgaatgtggccaaggtcattggaaccaacccgtgtgctgat gggaatggggggtgcagccacctctgcttcttcacaccccgagccactaagtgtggctgc cccatcggcctggagctgctgagtgacatgaagacctgcatcgtccctgaggccttcctg gtgttcaccagccgggccgccatccacagaatctccctggagaccaacaacaacgacgtg gccatccctctcactggggtcaaggaggcctccgcgcttgactttgacgtgtctaacaat cacatctactggacagatgtcagcctgaagaccatcagccgagccttcatgaacgggagc tctgtggagcacgtgatcgagtttggcctggactaccctgaaggcatggccgtggactgg atgggcaagaacctctactgggccgacaccgggaccaacaggattgaggtggctcggctg gatgggcagttccggcaggtccttgtgtggagggacttggacaacccgaggtcactggct ctggatcccaccaaaggctacatttattggacagagtggggcggcaagccaaggattgtg cgggccttcatggatgggaccaactgcataacactggtggacaaggtgggccgggccaac gacctcaccattgattatgccgaccagcgtctctactggaccgacctggacaccaacatg atcgagtcatccaacatgctgggccaggagcgggtggtgatcgccgatgacctgccgcac cccttcggcctgacgcagtacagcaattacatctactggactgactggaacctgcatagc atcgagcgggctgacaagaccagtggccggaaccgcacccttgtccagggccacctggac tttgtgatggacatcctcgtgtttcactcctcccgccaggacggcctcaatgactgcgtg cacaacaacggccagtgcgagcagctctgcctcgccatccctggtggccaccgctgcggc tgtgcctcgcactacaccctggaccccagcagtcgcaactgtagcccaccttccaccttc ttgctgttcagccagaaatgtgcaatcagccggatgatccctgatgaccagcacagccca gacctcatcctgcccttacacgggctgaggaacgtcaaggccatcgactacgacccactg gacaagtttatctactgggtggatgggcgccagaacatcaagcgtgccaaggatgatggt tcccagacctttgttctgacctctccgggccaaagtccagacagacagccacatgacctt agcatcgacatctacagtcggacgttgttctggacgtgtgaggccgccaacaccatcaat gtccaccggctagatggggacgccatgggtgtggtgctccggggggaccgagacaagcca agagccatcacggtcaatgccgagcgagggtacctgtacttcaccaacatgcaggaccgt gcagctaagattgagcgtgcagccctggatggcacagagcgcgaggtcctcttcaccaca ggcctcatccgccctgtggccctcgtggtggacaatgctctgggcaagctcttttgggtg gatgcagacctgaagcgcattgaaagctgtgacctgtcaggggccaaccgcctgaccctg gaggacgcaaacatcgtgcagcctgtgggcctgacagttcttggccggcatctctactgg atagaccgccagcagcagatgatcgaacgtgtggagaagaccacgggggacaagcggact cgcatccaaggccgtgttgcccacctcacaggcatccatgctgtggaggaagtcaacctg gaggagttctcagcccacccatgtgcccgagacaacggcggctgctcccacatctgcatc gccaagggtgatgggacaccacggtgctcttgcccagtccatctcgtgctcctgcagaac ctgctgacctgtggtgagcctcctacttgctcccctgaccagtttgcatgtgccactggg gaaatcgactgcatccctggggcctggcgctgtgacggcttccccgagtgcgatgaccag agtgatgaggaaggctgccctgtgtgctcggctgcccagttcccctgtgcgcgtggccag tgcgtggacctgcgtctgcggtgtgacggtgaggccgactgccaggaccgctctgatgag gctgactgcgatgctgtctgcctgcccaaccagttccggtgtgccagtggccagtgcgtc ctcatcaagcagcagtgcgactccttccctgattgcgtggatggctctgatgagctcatg tgtgaaattaccaagccgccctctgacgagaccccagcccacagcagcgccatcgggcct gtcattggcatcatcctcacactcttcatcatgggcggactctatttcgtgtgccagcgt gtggtgtgccagcgctactcgggggccagtgggcccttcccacatgagtacgtcagtggg accccccatgtgcccctcaatttcatagcccctggtggctcacagcatggtcctttccca ggcatctcctgcagcaagtccgtgatgagctccgtgagcctgatggggggccggagtggt gcacccctctatgaccggaaccatgtcactggggcctcgtccagcagctcgtccagcacg aaggccacactgtacccaccgatcctgaacccaccaccatccccagccacggacccctcc ctgtataacatggatatgttctactcttcaaacattccagctaccaccagagcgtacagg ccatatatcattcgaggcatggcacccccaacaacaccctgcagcacagatgtgtgtgac agcgactacagtgccagccgttggaaggccagcaagtactatctggatttgaactcagac tcagacccctacccacccccgcccacaccccacagccagtacctgtctgcagaagacagc tgcccgccctcgcctgtcactgagcggagctactgccacctcttcccacccccgccgtcc ccctgcacagactcatcctga

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