KEGG   Heterocephalus glaber (naked mole-rat): 101712827
Entry
101712827         CDS       T02812                                 
Symbol
Cacna2d3
Name
(RefSeq) calcium voltage-gated channel auxiliary subunit alpha2delta 3
  KO
K04860  voltage-dependent calcium channel alpha-2/delta-3
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04010  MAPK signaling pathway
hgl04260  Cardiac muscle contraction
hgl04261  Adrenergic signaling in cardiomyocytes
hgl04921  Oxytocin signaling pathway
hgl05410  Hypertrophic cardiomyopathy
hgl05412  Arrhythmogenic right ventricular cardiomyopathy
hgl05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101712827 (Cacna2d3)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    101712827 (Cacna2d3)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    101712827 (Cacna2d3)
   04261 Adrenergic signaling in cardiomyocytes
    101712827 (Cacna2d3)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101712827 (Cacna2d3)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    101712827 (Cacna2d3)
   05414 Dilated cardiomyopathy
    101712827 (Cacna2d3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hgl04040]
    101712827 (Cacna2d3)
Ion channels [BR:hgl04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   101712827 (Cacna2d3)
SSDB
Motif
Pfam: VWA_N VGCC_alpha2 dCache_1 VWA VWA_3 VWA_2 dCache_2 VWA_CoxE Phage_holin_6_1
Other DBs
NCBI-GeneID: 101712827
NCBI-ProteinID: XP_004864388
UniProt: A0AAX6Q372
LinkDB
Position
Un
AA seq 1089 aa
MAGPGSPRRASRGAPLLAAALLYAALGAVVLAEQQIPLSVVKLWASAFGGEIKSIAAKYS
GSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHE
FDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYNK
DPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDC
RNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEEL
HYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSIC
SQALMLITDGAVDTYDAIFAKHNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQI
STLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLADDQGLVLMTTVAM
PVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRP
LYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMT
NDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTVEEGLHDLEHPDVSLADEWSYCNTDLH
PEHRHLSQLEAIKLYLKGKEALLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDK
GVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGSF
VYSIPFSTGTVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCASL
DGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEVEGAVMNKLLTMGSFKRITLY
DYQAMCRANKESSDGAHGLLDPYNAFLSAMKWIMTELVLFLVEFNLCSWWHSDMTAKAQK
LKQTLEPCDTEYPAFVSERTIKETTGNIVCEDCSKSFVIQQIPSSNLFMVVVDSSCPCES
MGPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSLQAMRALLL
SLLLILFSR
NT seq 3270 nt   +upstreamnt  +downstreamnt
atggcagggccgggctcgccgcgccgcgcgtcccggggggccccgctcctggccgccgcg
ctcctctacgccgcgctgggggccgtggtgctcgcggagcagcagatcccgctctccgtg
gtgaagctgtgggcctcggcttttggtggggagataaaatccattgctgctaagtactca
ggctcgcagcttctgcaaaagaaatacaaggaatatgagaaagacgttgccatagaagaa
atcgatggcctccagctggtgaaaaagctggcaaagaacatggaagagatgtttcacaag
aagtccgaggcagtgcggcgtcttgtggaggctgcagaagaggcgcacctgaaacatgaa
tttgatgcagacttacagtatgaatacttcaatgctgtgctgataaatgaaagagacaaa
gatgggaactttctggaactggggaaagaattcatcttagcccccaatgatcattttaat
aatttgccagtgaacatcagtctgagtgatgtccaagtgccaacgaacatgtacaacaaa
gatcctgcgattgtcaatggagtttattggtccgagtccctaaacaaagttttcgtagat
aactttgaccgcgacccgtccctcatatggcagtactttggaagcgcaaagggctttttt
aggcagtatccagggattaaatgggaaccagatgagaatggagtcattgcctttgactgc
aggaatcgaaaatggtacatccaggcagcgacttctccgaaagatgtggtcattttggtt
gacgtcagtggcagcatgaaaggactccgtttgactattgcgaagcaaacagtctcatct
attctggatacgctgggggatgatgacttcttcaacattatcgcttataatgaggagcta
cactacgttgagccttgcctgaatggaacgctggtacaagctgacaggacaaacaaagag
cacttcagggagcatctggacaaactttttgccaaaggaatcggaatgctggatatagct
ctgaacgaggccttcaacattctcagcgatttcaaccatacgggacaagggagcatctgc
agtcaggccctcatgctcataactgatggggcagtggacacctacgatgccatctttgca
aaacacaattggcccgaccgaaaggttcgtatctttacatacctcatcggccgggaggct
gcctttgcagacaatctcaagtggatggcctgtgccaacaaaggatttttcacacagatc
tctaccttggcggacgtgcaggaaaatgtcatggaatacctacacgtgctgagccggccc
aaggtcatcgaccaggagcatgatgtggtatggaccgaagcttacatcgacagcactctc
cctcaggctcaaaagcttgctgatgatcagggcctcgttctgatgaccacggtggccatg
cccgtgtttagtaaacagaatgaaacccgatcgaagggcattcttctgggtgtggttggc
acagatgtcccagtgaaggaacttctgaagaccatccccaagtacaagctagggattcac
ggttatgcgtttgcaatcacaaataatggatacatcctgacgcatccagagctcaggcca
ctgtatgaagaaggaaagaagcgaaggaaacctaactatagtagtgttgacctctctgag
gtggaatgggaagaccgagatgatgtgttaagaaacgccatggtgaatcgaaaaacgggg
aagttttccatggaggtgaagaagactgtggacaaagggaaacgggttttggtgatgaca
aatgactactattatacagacatcaagggtactcctttcagtttaggtgtggcgctctcc
agaggccatgggaagtatttcttccgaggaaacgtgaccgtcgaggaaggcttgcatgac
ttggaacaccccgatgtgtccctggcagatgaatggtcctactgcaacactgacctgcac
cctgagcaccgtcatctgtctcaattagaagccattaagctctacctgaaaggcaaagag
gctttgctccagtgtgataaagagttgatccaagaagtcctttttgacgctgtggtgagt
gcccctatcgaagcatactggaccagcctggccctcaacaaatctgagaactctgacaag
ggcgtcgaggtcgctttccttggcactcgcacgggcctctcaagaatcaacctgtttgtt
ggggctgagcagctcaccaatcaggacttcctgaaagctggagacaaagagaacattttt
aacgcagaccatttccctctgtggtaccgaagagctgctgagcagattccagggagcttc
gtctactcgatccctttcagcacaggaacagtcaacaaaagcaatgtggtaacagcaagt
acctccatccagctcctggatgagcggaaatctcctgtggtggcagctgtaggcattcag
atgaaactcgaatttttccaaaggaagttctggactgccagcagacagtgtgcttccttg
gatggcaagtgctccatcagctgcgatgatgagactgtgaactgttacctcatagacaat
aatggatttatcctggtgtctgaagactacacccagactggagacttctttggtgaggtc
gagggagctgtgatgaacaaattgttaacaatgggctcctttaaaagaattaccctttat
gactaccaagccatgtgtagagccaacaaggagagcagcgacggtgctcatgggctcctg
gatccttataatgccttcctctctgccatgaaatggataatgacagaacttgtcttgttc
ctggtggaatttaacctctgcagttggtggcactctgatatgacagctaaagcccagaaa
ctgaagcagaccctggagccttgtgatactgaatatccagcatttgtgtctgagcgcact
atcaaggagaccacagggaacattgtttgcgaagactgctccaagtcctttgtcatccag
caaatcccaagcagcaatctgttcatggtggtagtggacagcagctgcccgtgtgagtcc
atgggccccatcaccatggcacccattgaaatcaggtataatgaatcccttaagtgtgaa
cgtttaaaggctcagaagatcagacggcgtccagaatcttgtcatggcttccatcctgag
gagaatgcgagggagtgtgggggtgcgccgagtctccaggccatgagggccctcctgctc
tctctgcttctgatactcttctcgaggtga

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