Heterocephalus glaber (naked mole-rat): 101713528 Help Entry 101713528         CDS       T02812                                  Symbol Pld2 Name (RefSeq) phospholipase D2   KO K01115   phospholipase D1/2 [EC:3.1.4.4] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00564   Glycerophospholipid metabolism hgl00565   Ether lipid metabolism hgl01100   Metabolic pathways hgl04014   Ras signaling pathway hgl04024   cAMP signaling pathway hgl04071   Sphingolipid signaling pathway hgl04072   Phospholipase D signaling pathway hgl04144   Endocytosis hgl04666   Fc gamma R-mediated phagocytosis hgl04724   Glutamatergic synapse hgl04912   GnRH signaling pathway hgl04928   Parathyroid hormone synthesis, secretion and action hgl05200   Pathways in cancer hgl05208   Chemical carcinogenesis - reactive oxygen species hgl05212   Pancreatic cancer hgl05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     101713528 (Pld2)    00565 Ether lipid metabolism     101713528 (Pld2)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     101713528 (Pld2)    04072 Phospholipase D signaling pathway     101713528 (Pld2)    04071 Sphingolipid signaling pathway     101713528 (Pld2)    04024 cAMP signaling pathway     101713528 (Pld2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     101713528 (Pld2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     101713528 (Pld2)   09152 Endocrine system    04912 GnRH signaling pathway     101713528 (Pld2)    04928 Parathyroid hormone synthesis, secretion and action     101713528 (Pld2)   09156 Nervous system    04724 Glutamatergic synapse     101713528 (Pld2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101713528 (Pld2)    05208 Chemical carcinogenesis - reactive oxygen species     101713528 (Pld2)    05231 Choline metabolism in cancer     101713528 (Pld2)   09162 Cancer: specific types    05212 Pancreatic cancer     101713528 (Pld2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hgl04131]     101713528 (Pld2) Enzymes [BR:hgl01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.4  phospholipase D      101713528 (Pld2) Membrane trafficking [BR:hgl04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     101713528 (Pld2)  Endosome - Golgi transport   Others    Others     101713528 (Pld2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLDc PLDc_2 PX PH PH_2 Motif Other DBs NCBI-GeneID:  101713528 NCBI-ProteinID:  XP_004857340 UniProt:  A0AAX6RBW0 LinkDB All DBs Position Un AA seq 936 aa AA seqDB search MIATQECPFPYGDYLDSSQLHMEPDEVNTLREGEDPADRMHPFLAIYDLQPLKVHPLVFA PGVSVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLQRHKVL MSLLPLARFAVAYSPAQEAADRANREMPSLPRGGPEGSTRHAASKQKYLENYLNHLLTMS FYRNYHAMTEFLEVSQLSFIPDLGPKGLEGVIRKRSGGHRLPGLTCCGRDQVCYRWSKRW LVVKDSFLLYMCLETGVISFVQLFDSGFEVQVGKRSTETRYGVRIDTSHRSLILKCSSYR QARWWGQEITELAQGPGKDFLRLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRARE EIFITDWWLSPEVYLKRPAHSDDWRLDIMLKKAAEEGVRVSVLLFKEVELALGINSGYSK RTLMLLHPNIKVMRHPDQMTLWAHHEKLLVVDQAVAFLGGLDLAYGRWDDLHYRLTDLGD SSESGASQTPTPCTDSAATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPR MPWRDVGVVVHGLAARDLARHFIQRWNFTKTTKAKYKTPMYPYLLPKSTSTANQLPFTIP GGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESKHFLYIENQFFISCSDGRTVLNKV GDEIVDRILKAHKQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSI LHRLKAAMGTAWRDYMSICGLRTHGELGGHPVSELIYIHSKMLIADDRTVIIGSANINDR SLLGKRDSELAVLIEDTEMVPSLMDGMEYQAGRFALSLRKHCFSVILGANAWPDLDLQDP VCDDFFQLWQETAENNANIYEQIFRCLPSNATRSLRTLREYVAVEPLAVVSPPLARSELT EIQGHLVHFPLKFLEDESLLPSLGSKEGMIPLEVWI NT seq 2811 nt NT seq  +upstreamnt  +downstreamnt atgattgctacccaggaatgccccttcccctatggggactacctggactccagccagtta cacatggagccggatgaagtcaacaccctgagggagggagaggacccagctgaccgaatg catccctttctggccatctatgaccttcagcctctgaaagtgcaccccttggtgtttgcc cctggggtctctgtcatagcccaggtagtgggaactgaaagatacaccagtggatccaag gtgggaacctgcactctgtattctgtccgcttgactcatggtgactttacctggacaacc aagaagaagttccgtcatttccaggagctacatcgggacctccagagacacaaagtcttg atgagtttgctccctctggctcgctttgctgttgcctattctccagcccaagaggcagcc gacagagccaacagagagatgccctctctaccccgaggaggacctgagggctccaccaga catgcagccagcaaacagaaatatctggaaaattatctcaaccacctcctgaccatgtct ttctaccgaaactaccatgctatgacagaattcctggaagtcagtcagctctcctttatc ccggacctgggacccaaaggactggagggggtgatccggaagcgctcaggtggccaccgt cttcctggcctcacctgttgtggtcgagaccaagtctgttaccgctggtccaagaggtgg ctggtggtgaaagactccttcctgctgtacatgtgtctggagactggtgtcatctctttt gttcagctctttgactctggctttgaggtgcaggtggggaaacggagcacagagacacgg tatggggtgcggatcgacacctcccacaggtccctgattctcaagtgcagcagctaccgg caggcacgatggtggggccaggagatcacagagctggcacagggcccggggaaagacttc ctacggctgcaccagcatgacagctatgccccaccccggcctgggaccttggcccggtgg tttgtgaatggggcaggttactttgctgctgtggcagatgccatcctgcgagcccgagag gagatttttatcacagactggtggctgagtcctgaggtttacctgaagcgcccagcccat tcggacgactggaggctggacattatgctcaagaaggcagcggaggagggtgttcgtgtg tctgttctgctgtttaaggaagtggaattggccttgggcatcaacagtggctatagcaag aggacactgatgctgctacaccccaacataaaggtgatgcgccatccagaccagatgaca ctgtgggctcatcatgagaagctcctagtggttgaccaagcagtggccttcctggggggg ctggacctcgcctatggccgctgggatgaccttcactaccgactgaccgaccttggggac tcatctgaatcaggtgcctcacagactcccaccccatgcacagactctgcagccacccca gacctctctcacaaccaattcttctggctgggcaaggactacagcaatctcatcactaag gactgggtgcaattagaccggccttttgaagatttcattgacagggagaccacaccccgg atgccatggagggatgttggggtggttgtccatggcttagctgcccgtgaccttgcccgg cacttcatccagcgctggaacttcaccaagaccaccaaggctaagtacaagacacctatg tacccctatctgctacccaagtccaccagcactgcaaaccagctccctttcacaatccct ggtgggcagtgcaccactgtgcaggtcttgcggtctgtggaccgctggtcagcggggacg ctggagaactccatccttaatgcctacctgcacaccatcagggagagcaagcacttcctc tacattgagaatcagttcttcattagctgctcagatgggcgcacggtcctgaacaaggtg ggcgatgagattgtggacagaatcctgaaggcccacaagcaggggcagtgtttccgagtc tatgtgcttctgcccttgctccctggctttgagggtgacatctccacaggtggtggtaac tctatccaggccattctgcacttcacatacaggaccctgtgtcgaggcgagtattcaatc ctacatcgcctcaaagcagccatggggacagcatggcgggactacatgtccatctgtggg cttcgcacacacggagagctgggcgggcacccagtctcagagctcatctatattcacagc aagatgcttattgcagatgaccggacggtcatcattggttctgcaaacatcaatgaccgg agcttgctagggaagcgggacagtgagctggctgtgctgatcgaggacacagagatggtg ccatcccttatggatggaatggagtatcaggcaggcaggtttgccttgagtttgcggaag cactgtttcagtgtgattcttggggcaaatgcctggccagacctggatctgcaagaccca gtctgtgatgacttcttccagttgtggcaagaaacagcagagaacaatgccaatatctat gagcagatcttccgatgcctgccgtccaatgccacgcgttccctgcggactctccgggag tacgtggctgtggagcccctggctgtggtcagtcctcccttggcccgatctgagctcact gaaatccagggccacctggttcactttcccctcaagttcctggaggatgaatctttgctg ccctcactggggagcaaggagggcatgatacccctagaagtatggatatag

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