Heterocephalus glaber (naked mole-rat): 101714134
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Entry
101714134 CDS
T02812
Symbol
Pdhb
Name
(RefSeq) pyruvate dehydrogenase (lipoamide) beta
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00010
Glycolysis / Gluconeogenesis
hgl00020
Citrate cycle (TCA cycle)
hgl00620
Pyruvate metabolism
hgl00785
Lipoic acid metabolism
hgl01100
Metabolic pathways
hgl01200
Carbon metabolism
hgl01210
2-Oxocarboxylic acid metabolism
hgl04066
HIF-1 signaling pathway
hgl04922
Glucagon signaling pathway
hgl05230
Central carbon metabolism in cancer
hgl05415
Diabetic cardiomyopathy
Module
hgl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101714134 (Pdhb)
00020 Citrate cycle (TCA cycle)
101714134 (Pdhb)
00620 Pyruvate metabolism
101714134 (Pdhb)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101714134 (Pdhb)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101714134 (Pdhb)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101714134 (Pdhb)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101714134 (Pdhb)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101714134 (Pdhb)
Enzymes [BR:
hgl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101714134 (Pdhb)
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Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-GeneID:
101714134
NCBI-ProteinID:
XP_004864490
UniProt:
G5BUK7
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All DBs
Position
Un
AA seq
359 aa
AA seq
DB search
MAALSGLARRPLQQVSGLLKRHFHRSAPAALQVTVRDAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSAGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNA
EDAKGLIKSAIRDNNPVVMLENELMYGVAFEFPAEAQSKDFLIPIGKAKIERQGTHITVV
SHSRPVGHCLEAATVLSKEGVECEVINLRTIRPMDIETIEASVMKTNHLVTVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgtcggggctggcgcggagacccctacagcaggtttccgggctgctgaag
aggcactttcaccggagcgcgcccgctgcgctgcaggtaacagttcgtgatgctatcaat
caaggtatggatgaggagctggagagagatgagaaggtatttctgcttggggaagaagtt
gcccaatacgatggggcatacaaggttagtcggggcctgtggaagaagtacggagacaag
aggatcatagacactcccatatctgagatgggctttgctggaattgctgtgggtgcagct
atggctgggttgcggcccatttgtgaatttatgaccttcaatttctctatgcaagccatc
gaccaggtgataaactcagctgccaagacctactacatgtcggcagggctccagcctgtg
cccatcgtgttcagggggcccaatggtgcctcagcaggtgtcgctgctcagcactcacag
tgcttcgctgcgtggtatgggcactgcccaggcttgaaggtggtcagcccctggaatgca
gaggatgcaaaaggacttattaagtcagccattcgggataacaatccagtggtgatgcta
gagaatgaactgatgtatggagttgcttttgaatttcctgcagaagctcagtcaaaagat
tttctgattcctattggaaaagccaagatagaaaggcaagggacacatataactgtggtt
tcccattcgagacctgtgggccattgcttagaagctgcgacagtgctgtctaaagaagga
gttgaatgtgaggtgataaatttgcgtaccattagaccaatggacattgaaaccatcgaa
gccagtgtcatgaagactaaccatcttgtaactgtggaaggaggctggccgcagtttgga
gtgggagctgaaatttgtgccaggatcatggaaggtcctgcattcaatttcttggatgct
cctgctgttcgcgtcactggtgctgatgtccctatgccttatgcaaagattttagaagac
aactctgtacctcaggtcaaagacatcatatttgcaataaagaaaacattaaatatctag
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