KEGG   Heterocephalus glaber (naked mole-rat): 101714852
Entry
101714852         CDS       T02812                                 
Symbol
Gsta1
Name
(RefSeq) glutathione S-transferase A1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis - DNA adducts
hgl05207  Chemical carcinogenesis - receptor activation
hgl05208  Chemical carcinogenesis - reactive oxygen species
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101714852 (Gsta1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101714852 (Gsta1)
   00982 Drug metabolism - cytochrome P450
    101714852 (Gsta1)
   00983 Drug metabolism - other enzymes
    101714852 (Gsta1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101714852 (Gsta1)
   05204 Chemical carcinogenesis - DNA adducts
    101714852 (Gsta1)
   05207 Chemical carcinogenesis - receptor activation
    101714852 (Gsta1)
   05208 Chemical carcinogenesis - reactive oxygen species
    101714852 (Gsta1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101714852 (Gsta1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101714852 (Gsta1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101714852 (Gsta1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101714852 (Gsta1)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101714852 (Gsta1)
Transporters [BR:hgl02000]
 Other transporters
  Pores ion channels [TC:1]
   101714852 (Gsta1)
SSDB
Motif
Pfam: GST_C GST_N GST_C_3 GST_N_3 GST_N_2
Other DBs
NCBI-GeneID: 101714852
NCBI-ProteinID: XP_004869083
UniProt: G5BC72
LinkDB
Position
Un
AA seq 222 aa
MAGKPVLHYFNGRGRMESIRWLLAAAGVEFEEKLIKCPEDFEKLKNEGLLMFQQVPMVEM
DGMKLVQSRAILNYIATKYNLYGKDMKERLLIDMYIEGIMDLYEMISHLALTPPDQTDTK
MALIRDKTKNCYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYCVEEVDASLLAAFPL
LQALKTRISNLPNVKKFLQPGSQRKPPTTAKMIEEARKVFKF
NT seq 669 nt   +upstreamnt  +downstreamnt
atggcagggaagccggtgcttcactacttcaatggacggggcaggatggagtccatccgg
tggctcttggctgcagctggagtagagtttgaagagaagcttataaaatgtccagaagat
tttgaaaagttaaaaaatgaagggcttttgatgttccagcaagtacccatggtggagatg
gatgggatgaagctggtgcagtccagagccattctcaactacattgccaccaaatacaac
ctctatgggaaagatatgaaagagagactcctgattgatatgtacatagaaggcatcatg
gatttatatgaaatgatctcacatctggcactgactcctccagatcaaacagataccaag
atggctttgatcagagacaaaacaaagaattgctacttccctgcctttgaaaaagtgtta
aagagtcatggacaagactaccttgttggcaacaagctgagcagggctgacattcacctg
gttgaacttctctactgtgttgaagaggttgatgcgagtcttttggctgctttccctctg
ctgcaggctctaaaaaccagaatcagtaacctgcccaatgtgaagaagtttctgcagcct
ggcagccagaggaagcctcccactactgcaaaaatgatagaagaagccagaaaggttttc
aagttttag

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