Heterocephalus glaber (naked mole-rat): 101715845
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Entry
101715845 CDS
T02812
Symbol
Hif1a
Name
(RefSeq) hypoxia inducible factor 1 alpha subunit
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04066
HIF-1 signaling pathway
hgl04137
Mitophagy - animal
hgl04140
Autophagy - animal
hgl04148
Efferocytosis
hgl04659
Th17 cell differentiation
hgl04919
Thyroid hormone signaling pathway
hgl05167
Kaposi sarcoma-associated herpesvirus infection
hgl05200
Pathways in cancer
hgl05205
Proteoglycans in cancer
hgl05208
Chemical carcinogenesis - reactive oxygen species
hgl05211
Renal cell carcinoma
hgl05230
Central carbon metabolism in cancer
hgl05231
Choline metabolism in cancer
hgl05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101715845 (Hif1a)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101715845 (Hif1a)
04137 Mitophagy - animal
101715845 (Hif1a)
04148 Efferocytosis
101715845 (Hif1a)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
101715845 (Hif1a)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
101715845 (Hif1a)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101715845 (Hif1a)
05205 Proteoglycans in cancer
101715845 (Hif1a)
05208 Chemical carcinogenesis - reactive oxygen species
101715845 (Hif1a)
05230 Central carbon metabolism in cancer
101715845 (Hif1a)
05231 Choline metabolism in cancer
101715845 (Hif1a)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101715845 (Hif1a)
09162 Cancer: specific types
05211 Renal cell carcinoma
101715845 (Hif1a)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
101715845 (Hif1a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hgl03000
]
101715845 (Hif1a)
Transcription factors [BR:
hgl03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
101715845 (Hif1a)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
101715845
NCBI-ProteinID:
NP_001297196
UniProt:
A0AAX6NP19
A0A0A7HSI3
LinkDB
All DBs
Position
Un
AA seq
828 aa
AA seq
DB search
MEGPGGASDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDFEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMKEMLTHRNGPVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNNNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKITQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDIIISLDFSSNDTET
DDQQLEEVPLYNDVMFPSSSEKLQNINLAMSPLPASESPKPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSDYCFDVDSDMVNVFKLELVEKLF
AEDTEAKNPFSTQDNDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPQSVSTTTVFQ
QTQMQEPTVTTTTANTTTPPTTEELKSVTKDSMEDIQILIVSPSPTHLLKETAHATTSSP
YSNTPSRTTSPNRAGKGAIEQTEKSHPRSPNVVPVTLSQRNTIPEEELNPKIQALQNAQR
KRKMEHDGSLFQAVGIGTLLQQSDDRAATTSLSWKRVKGCKSSEQNGTEQKTIILIPSDL
ACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2487 nt
NT seq
+upstream
nt +downstream
nt
atggagggccccggtggcgcgagcgacaagaaaaagataagttctgagcgtcgaaaagaa
aagtctagagacgcagccagatctcggcgaagcaaagagtctgaagtattttatgagctt
gctcatcagttgccacttccccataatgtgagctcacatcttgataaggcttctgttatg
aggcttaccatcagttatttgcgtgtgagaaaacttctggatgctggtgatctggatttt
gaagatgaaatgaaagcacagatgaactgcttttatttgaaggccctggatggctttgtt
atggtgctcactgatgatggtgacatgatttacatttctgataacgtgaacaaatacatg
gggttaactcagtttgaactaactggacacagtgtgtttgattttactcatccgtgtgac
catgaggaaatgaaagaaatgcttacacacagaaatggccctgtgaaaaagggtaaagaa
caaaacacacagcgaagcttttttctcaggatgaagtgtaccctaactagcagggggcga
actatgaacataaagtctgcaacatggaaggtacttcactgcacaggccatattcacgta
tatgataccaacaataatcagtctcagtgtggatataagaaaccacccatgacatgcttg
gtgctgatttgcgaacctattcctcatccatccaatattgaaattcctctagatagcaag
acttttctcagtagacacagcctggatatgaaattttcttattgtgatgaaagaattact
gaattgatggggtatgagccagaagaacttctgggccgctcaatttatgaatattaccat
gctttggactctgatcatctgaccaaaactcaccatgacatgtttactaaaggacaggtc
accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gcaactgtcatatacaacaccaagaactctcagccacaatgcattgtgtgtgtaaattat
gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
ctcaaaccagttgaatcttcagatatgaaaataactcagctgttcaccaaagttgaatca
gaagatacaagtagtctctttgataagcttaagaaggaacctgatgctttaactttgctg
gccccagctgctggagacataatcatatctttagattttagcagcaatgacacagaaact
gatgaccaacaacttgaggaagttccattatataatgatgtaatgttcccctcatccagt
gaaaaattacagaatataaatttggcaatgtctccattacctgcctctgaatctccaaag
ccacttcggagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagaacca
aatccagagtcactggaactttcttttaccatgccccagattcaagatcagccagccagt
ccttctgatggaagcactagacaaagttcacctgagcctaacagtcccagtgactattgt
tttgatgtggatagtgatatggttaatgtattcaagttggaactggtagagaaacttttt
gctgaagatacagaagcaaaaaatccattttcaacccaggacaatgacttagacttggag
atgttggcaccctatatcccaatggatgatgatttccagttacgctcttttgatcagctg
tcaccattagaaagcagttctgcaagcccgcaaagtgtgagcacgactacagtattccag
cagactcaaatgcaagaacctaccgttaccaccaccactgccaacaccaccacacctccc
accacagaggaattaaaatcagtgacaaaagacagtatggaagacattcaaatactaatt
gtatctccgtctcctacccacctacttaaagaaactgctcatgccacaacatcatcacca
tacagcaatactccaagtcggaccacctcaccaaacagggcaggaaaaggagccatagag
cagacagaaaaatctcatccaagaagtcctaatgtggttcctgttactttgagtcagaga
aataccattcccgaggaagaactaaatccaaagatacaagctttgcagaatgctcagaga
aagcgaaaaatggaacatgatggttcactttttcaagcagtaggaattggaacattacta
cagcaatcagatgaccgtgcggctactacatcactttcttggaaacgcgtgaaaggatgc
aaatctagtgaacagaatggaacggagcaaaagacaattattttaataccctctgattta
gcatgtagactgctggggcaatcaatggatgaaagtggattaccacagctgaccagttac
gattgtgaagttaatgctcccattcaaggcagcagaaacctactgcaaggtgaagaatta
ctcagagctttggatcaagttaactga
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