Heterocephalus glaber (naked mole-rat): 101717491 Help Entry 101717491         CDS       T02812                                  Symbol Pla2g4d Name (RefSeq) phospholipase A2 group IVD   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00564   Glycerophospholipid metabolism hgl00565   Ether lipid metabolism hgl00590   Arachidonic acid metabolism hgl00591   Linoleic acid metabolism hgl00592   alpha-Linolenic acid metabolism hgl01100   Metabolic pathways hgl04010   MAPK signaling pathway hgl04014   Ras signaling pathway hgl04072   Phospholipase D signaling pathway hgl04217   Necroptosis hgl04270   Vascular smooth muscle contraction hgl04370   VEGF signaling pathway hgl04611   Platelet activation hgl04664   Fc epsilon RI signaling pathway hgl04666   Fc gamma R-mediated phagocytosis hgl04724   Glutamatergic synapse hgl04726   Serotonergic synapse hgl04730   Long-term depression hgl04750   Inflammatory mediator regulation of TRP channels hgl04912   GnRH signaling pathway hgl04913   Ovarian steroidogenesis hgl04921   Oxytocin signaling pathway hgl05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     101717491 (Pla2g4d)    00565 Ether lipid metabolism     101717491 (Pla2g4d)    00590 Arachidonic acid metabolism     101717491 (Pla2g4d)    00591 Linoleic acid metabolism     101717491 (Pla2g4d)    00592 alpha-Linolenic acid metabolism     101717491 (Pla2g4d)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101717491 (Pla2g4d)    04014 Ras signaling pathway     101717491 (Pla2g4d)    04370 VEGF signaling pathway     101717491 (Pla2g4d)    04072 Phospholipase D signaling pathway     101717491 (Pla2g4d)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101717491 (Pla2g4d)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101717491 (Pla2g4d)    04664 Fc epsilon RI signaling pathway     101717491 (Pla2g4d)    04666 Fc gamma R-mediated phagocytosis     101717491 (Pla2g4d)   09152 Endocrine system    04912 GnRH signaling pathway     101717491 (Pla2g4d)    04913 Ovarian steroidogenesis     101717491 (Pla2g4d)    04921 Oxytocin signaling pathway     101717491 (Pla2g4d)   09153 Circulatory system    04270 Vascular smooth muscle contraction     101717491 (Pla2g4d)   09156 Nervous system    04724 Glutamatergic synapse     101717491 (Pla2g4d)    04726 Serotonergic synapse     101717491 (Pla2g4d)    04730 Long-term depression     101717491 (Pla2g4d)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101717491 (Pla2g4d)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101717491 (Pla2g4d) Enzymes [BR:hgl01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      101717491 (Pla2g4d) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 DUF5958 7TMR-HDED Motif Other DBs NCBI-GeneID:  101717491 NCBI-ProteinID:  XP_004861794 LinkDB All DBs Position Un AA seq 858 aa AA seqDB search MENLSPKRSPGHLHKGEASACWRLTVRVLEAWRLHRVDLLSEADPYVILQLPTSPGMKFR TKTVSNSSHPVWNETFSFLIQSRVKNVLELGIYDEDLITKDDICFKVFYDISEVLPGKLL QKTFFLGPQGQEELDVEFLVEETPGPPEYLITNNVLVARELSRLDVHLDRAGSTPGGADW GKLELELVLKGSFEDTQTSALGTASAFRFHYLAAQDTELHGRLKSSRSSGWNTDSSAGHF TVPLQSLAGGREVTICVPATDDPGVRLQLKADSCPKELDVRLGFDLCVEEQAFLSRRKQV VAMALKQALQLDRDLQEEEVPVVGIMAEGGGARAMTSLCGHLLALQKLGLLDCVTYLSGI SGATWAMAHLYGDPEWSQKDLQGPISHIRKHMAKSKLRAFSPQSLASYWHKLQLRASQGH PTTAVDLWALLLEFSLHGQVADQTLSGQRDALERGQNPLPLYLSLNVKEDTVDTLHFKEW VEFTPYEVGFLKYGAFVPPELFGSEFFMGRLMRRLPESPICFLEAIWSNIFSLNLMDTWY NLAWSGEEWKQHVKEEIHSTEEPEDCLRTSLWTEASWLQPGTALARAFKGVLTGRPLCHH GANFLHGLQLHQGYSGQKDFSTWADCQSDSTPSQLTPQQPQLCLVDAGYLINNSYPSMFR PGRRLDLILYFGYSLSSHFEALQQAELYCRTQGLHFPHVEISAEDRCQPRECYLFADPTC PEAPVLLYFPLVNVSFKDHSTPGVWRSPEELWAGQVDLNKTTTPYFLLNMTYSEEDFDHL LQLNDYNLQNSQDTILQALRMALKHRAPEARPQGAQLLRVVHGAVGSRGVLSLASRERGS ALKQPEKCCWEEKAVREY NT seq 2577 nt NT seq  +upstreamnt  +downstreamnt atggaaaacctgtcacctaagagatcacctggccatctgcacaagggggaggcctctgcc tgctggcggctcaccgtgcgggtcctggaggcgtggagactacaccgggttgacttgttg agtgaggccgacccgtatgtgatcctgcagctgccaacctctcctgggatgaagttcagg accaaaacggtctccaactccagccatcctgtgtggaatgagaccttcagtttcctcatc cagagtcgggtcaagaatgttctggagctgggcatctatgacgaagatttaattacaaag gatgacatctgcttcaaggttttctatgacatctcagaagtccttcctggcaagctgctc cagaaaaccttcttcctgggtccccagggacaggaagagctggacgtggagttcctagta gaagaaacgcccggccctccagaatacctgatcaccaacaatgtcctcgtggcccgggag ctgtcacgcctggacgtccatctggacagagcagggagcacccctgggggagcagactgg ggcaagctggagctggagctggtgctgaaggggtcctttgaagacacgcagacgtctgcc ctgggcacagcctctgccttccgcttccattacctggcagcccaggacacagagctgcat gggcgcctgaagagctccagaagcagcggttggaacacagacagctcagctgggcacttt actgtgcccctgcagtccttggccggggggagagaggtgaccatctgtgttcctgctaca gatgacccaggagtgagactgcagctcaaggcagacagctgccctaaggagctggatgtg cgcctgggctttgatctctgtgtggaggagcaggccttcctgagcaggaggaagcaggtg gtggccatggccctgaagcaggccctgcagctggacagagacctgcaggaggaagaggtc cctgttgtgggcatcatggcggaaggaggaggtgcccgggccatgacctctctctgcgga cacctactggccctgcagaagctgggcctcctggactgtgtgacctacctgagtggaatc tcgggtgctacgtgggcgatggcccacctgtacggggacccagagtggtcgcagaaggac ctccagggacccatcagccacatccggaagcacatggccaagagcaagctgagggccttc tctccacagagtctggcaagctactggcacaagctgcagctgcgggcctcacagggccac cccaccacggctgtggacctctgggccctcctgctggagttcagcctgcatggccaggtg gcggatcagacgctctcaggacagagagatgcactggagcggggtcagaaccctctgccc ctctatttgagcctcaatgtcaaagaggacactgtggacaccctccacttcaaggagtgg gtcgagttcaccccctatgaggttgggttcctgaagtacggagcttttgtgcctcctgag ctcttcggctccgagttcttcatggggcgactgatgaggaggctccctgagtccccgatc tgctttctggaagctatctggagcaacattttctccctgaacttgatggacacctggtat aacctggcctggtctggtgaggagtggaaacagcatgtcaaggaggagatacacagcaca gaggagcctgaggactgtttgaggacctctttatggacggaggcctcatggctgcagcct ggaacagccctggcacgggcatttaagggggtcctgacagggagaccactctgccaccat ggtgccaatttcctccatggcctccagctacaccagggctacagtggccagaaagacttc tctacctgggcagactgccagtcggactccacccctagccagctgaccccccagcaaccc cagctctgcctggtggacgctggctacttgatcaacaacagctatccctccatgttccgg ccaggccgcaggctagacctcatcctctacttcggctactccctgtcctcgcactttgag gccctgcagcaggctgagctgtactgtaggacccaggggctgcacttcccccacgtggag atcagtgctgaggaccgatgccagcccagggagtgctacctgtttgcggaccccacctgc ccagaggccccagtcctgctctacttccccctggtcaatgtctccttcaaggatcactcc acccctggtgtctggcgcagccccgaagagctctgggctggccaagtggatctcaacaag accaccacaccctatttcctgctcaacatgacctactcggaggaagactttgaccacctg ctgcaactgaatgactacaatctgcagaacagccaggacaccatcctgcaggccttgagg atggctctgaagcatagggccccagaggccaggcctcaaggggcccagctgctgagagtg gtccacggcgcggtggggtcgcggggcgtgctgagtctggcgtcccgagagcgtggaagc gccctgaagcagccggagaagtgctgctgggaagaaaaggctgtgcgggagtactga

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