Heterocephalus glaber (naked mole-rat): 101719685
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Entry
101719685 CDS
T02812
Symbol
Hsd17b2
Name
(RefSeq) hydroxysteroid 17-beta dehydrogenase 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00140
Steroid hormone biosynthesis
hgl01100
Metabolic pathways
hgl04913
Ovarian steroidogenesis
Module
hgl_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
101719685 (Hsd17b2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101719685 (Hsd17b2)
Enzymes [BR:
hgl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
101719685 (Hsd17b2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
101719685 (Hsd17b2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Epimerase
NmrA
PUMA_CC
Motif
Other DBs
NCBI-GeneID:
101719685
NCBI-ProteinID:
XP_004842843
UniProt:
G5BKQ7
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All DBs
Position
Un
AA seq
381 aa
AA seq
DB search
MIMVISEAAWFCLAVTAALGSIVFCKHKSPGQLGRPVVWLTGLCGGAYLLILSFFWSLVL
FSLLCFLMCMYLADQELLPVDQKAVLVTGCDSGFGHALAKNLDKLGFTVFAGVLNEKSSG
AEELRRNCSKHITVLQMDITNPEQIKDAHSKVIEKVQDKGLWALVNNAGILGFPTDGELI
PMIEYKKCMEVNFFGPVEVTKAFLPLLRKSKGRLVNVSSMGGVVPLPKFAAYNSTKAALT
MFSSIMRQELSAWGVKVSVVQPGGFRTNIAGTNDVWLKNEKDILDHLTQEQLRDYGRDYV
LLQKNFLNKFESFTCPDFTPVLRDIQHAISAQSPSPFYMPGKMVSLWVYFAFLSPTHLFD
YCVKKIFVKSEYIPRALHMPN
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atgatcatggtcatctctgaggcagcatggttctgcctggctgtcactgcagccctaggc
agcatagttttctgcaaacacaagagcccagggcagctggggagaccagtggtctggctc
actggactctgcggaggggcttacctgctcatcttgtccttcttctggagcttggttctc
ttctccttgttgtgtttcctcatgtgtatgtacttggctgaccaagagctgttacccgtg
gatcaaaaggcagtcctggtgacaggttgtgattctgggttcggccatgcattggccaag
aacttggacaagctgggcttcacagtattcgctggagttttgaatgaaaagagctcagga
gctgaggaattgcgaagaaactgctccaagcacatcactgtgcttcagatggacatcacc
aacccagaacagataaaagatgctcacagcaaagtcatagagaaggtgcaggacaaagga
ctgtgggctctggtcaacaatgctgggatccttggcttcccgacagatggggaacttatt
cccatgattgagtacaaaaaatgcatggaggtgaacttctttggacccgtagaagtcacg
aaggcatttttacctcttcttaggaaatctaaggggaggctggtgaatgtcagcagcatg
ggaggagtggtcccattgccaaagttcgcagcttacaactcaacgaaggcagctctgact
atgttttcttcaattatgaggcaagaactttctgcatggggagtaaaagtctctgtggtc
cagcctggaggcttccgaacaaatattgcaggcacaaatgatgtatggctcaagaacgaa
aaggacatcctggaccacctcacccaagagcagctgagggactatggccgggactatgtt
cttctgcagaagaatttcctcaataagtttgaaagctttacctgcccagactttacccca
gtgctccgggacatccaacatgccatctctgctcagagcccgtctcccttctatatgccg
gggaaaatggtttccctgtgggtctactttgccttcctttcccctacccacttatttgat
tattgtgttaaaaaaatatttgtcaagagtgagtatattcccagagctctacacatgcct
aactag
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