Heterocephalus glaber (naked mole-rat): 101720630
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Entry
101720630 CDS
T02812
Symbol
Atp2a2
Name
(RefSeq) ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04020
Calcium signaling pathway
hgl04022
cGMP-PKG signaling pathway
hgl04024
cAMP signaling pathway
hgl04148
Efferocytosis
hgl04260
Cardiac muscle contraction
hgl04261
Adrenergic signaling in cardiomyocytes
hgl04380
Osteoclast differentiation
hgl04919
Thyroid hormone signaling pathway
hgl04972
Pancreatic secretion
hgl05010
Alzheimer disease
hgl05017
Spinocerebellar ataxia
hgl05022
Pathways of neurodegeneration - multiple diseases
hgl05410
Hypertrophic cardiomyopathy
hgl05412
Arrhythmogenic right ventricular cardiomyopathy
hgl05414
Dilated cardiomyopathy
hgl05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
101720630 (Atp2a2)
04024 cAMP signaling pathway
101720630 (Atp2a2)
04022 cGMP-PKG signaling pathway
101720630 (Atp2a2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101720630 (Atp2a2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
101720630 (Atp2a2)
09153 Circulatory system
04260 Cardiac muscle contraction
101720630 (Atp2a2)
04261 Adrenergic signaling in cardiomyocytes
101720630 (Atp2a2)
09154 Digestive system
04972 Pancreatic secretion
101720630 (Atp2a2)
09158 Development and regeneration
04380 Osteoclast differentiation
101720630 (Atp2a2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101720630 (Atp2a2)
05017 Spinocerebellar ataxia
101720630 (Atp2a2)
05022 Pathways of neurodegeneration - multiple diseases
101720630 (Atp2a2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
101720630 (Atp2a2)
05412 Arrhythmogenic right ventricular cardiomyopathy
101720630 (Atp2a2)
05414 Dilated cardiomyopathy
101720630 (Atp2a2)
05415 Diabetic cardiomyopathy
101720630 (Atp2a2)
Enzymes [BR:
hgl01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
101720630 (Atp2a2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
101720630
NCBI-ProteinID:
XP_004843884
LinkDB
All DBs
Position
Un
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPIKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKALSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVASKAFTGREFDEL
SPPAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFAGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPPTKSCSFSACTDGISWPFVL
LIMPLVVWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacagtggaggaggtgctgggccacttcggcgtcaacgag
agcacagggctgagcctggagcaggtcaagaagctcaaggagagatggggctccaacgag
ttaccggctgaagaaggaaaaaccttgctggaactagtgattgagcagtttgaagattta
ctagttagaattttattgctggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaaccattacagcctttgtagaaccttttgtaattctacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgaaaatgcaattgaagccctaaag
gagtatgagcctgaaatgggcaaagtgtatcgacaggacagaaagagtgtacagcggatt
aaagctaaagatatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaagtctacgactctaagagtcgaccagtccattctc
actggtgaatctgtttcagtcatcaagcacactgaccctgtccctgacccacgggctgtc
aaccaagataagaagaacatgctcttttctggtacaaacattgctgctgggaaagccatg
ggagtggtggtggcaactggagttaacactgaaatcggcaagatccgagatgaaatggtg
gccacagaacaggagagaacacctcttcagcagaaactggatgagtttggcgaacagctt
tccaaagtcatctctctcatttgcattgcagtctggatcataaacattgggcactttaat
gatccagtgcacgggggctcctggatccgaggtgctatctactactttaagattgcagtg
gcgctggctgttgcagccatccctgagggtctgcccgctgtcatcaccacctgcctggcc
cttggaactcgcagaatggcaaagaaaaatgctattgttcgaagtcttccgtctgtggaa
acccttggttgtacttctgttatctgttcggacaagactggtacacttactacgaatcag
atgtcagtctgcaggatgttcattctggacaaagttgaaggtgacacttgttcccttaat
gagttcaccataactggctcaacgtatgcacccattggagaagtgcataaagatgataag
ccaataaaatgtcatcaatatgatgggcttgtagaattagcaaccatttgtgctctttgt
aatgactctgctttggattacaatgaggcgaaaggtgtatatgaaaaagttggagaagct
acagagactgctctcacttgcctggtagagaagatgaatgtatttgataccgaattgaag
gctctttctaaaatagaacgcgcaaatgcctgcaactcggtcattaaacagctaatgaaa
aaggaatttactttagagttttcacgtgataggaaatcaatgtctgtctactgcacacca
aacaaaccgagtcggacatccatgagcaagatgtttgtgaagggtgctccagaaggtgtc
atcgacaggtgtacccacattcgagttgggagtaccaaggtccccatgacccctggagtg
aaacagaagatcatgtctgtcattcgggagtggggcagtggcagtgatacgctgcggtgc
ctggccctggccactcacgacaacccacttcgaagagaagagatgcatctggaggactct
gccaacttcatcaaatatgagaccaacttgactttcgttggctgtgtgggcatgctggac
cctcccaggatcgaagtggcctcctctgtgaagctgtgtcggcaggcaggcattcgagtc
atcatgatcacgggggacaacaagggcaccgccgtggccatctgtcgccgcatcggtatc
tttggccaggatgaggatgtggcgtcaaaggcttttacaggtcgggagtttgatgaactc
agtcccccagctcagagagatgcctgcttgaatgcccgctgtttcgctagagtcgaacct
tctcacaagtctaagatcgtggagttccttcagtctttcgatgagatcacagctatgact
ggtgatggtgtgaatgacgctcctgctctgaagaaagctgagattggcattgctatgggt
tctggcactgcagtggctaaaactgcctccgagatggtcctggcagatgacaacttctcc
accatcgtggctgccgtggaggagggacgggccatctacaacaacatgaagcagttcatc
cgctacctcatctcgtctaatgtgggggaggttgtctgcattttcctgacagcagccctt
gggtttcccgaggctttaattcctgtacagctcctctgggtcaatctggtcacagatggc
ctgcctgccactgcgctgggcttcaaccctcctgatctggacatcatgaacaaaccaccc
cggaatccaaaggaaccactgatcagcggttggctctttttccgttacctggctattggc
tgttatgttggtgccgcgactgtgggtgctgctgcatggtggttcatcgctgccgatggt
ggtcccagagtgtccttctaccagctgagtcattttctacagtgtaaagaggacaaccca
gactttgcaggagtagattgtgccatctttgagtccccatacccgatgacaatggccctg
tctgttctagtaaccatagagatgtgtaacgccctcaacagcctatctgaaaaccagtcc
ttgctgaggatgcccccatgggagaacatctggctcgtggggtccatctgcctatcaatg
tccctccacttcctgatcctctacgtggagcctttgccactcatcttccagatcacaccg
ctgaacgtgacccagtggctgatggtgctgaaaatctccctgcctgtgattctcatggat
gagacgctcaagtttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
cccaccaaatcctgctcgttttcggcatgcaccgatgggatttcctggccgtttgtgctg
ctcataatgcccctggttgtctgggtctatagcacagacactaactttagtgatatgttc
tggtcttga
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