Heterocephalus glaber (naked mole-rat): 101721060
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Entry
101721060 CDS
T02812
Symbol
Atp1a4
Name
(RefSeq) ATPase Na+/K+ transporting subunit alpha 4
KO
K01539
sodium/potassium-transporting ATPase subunit alpha [EC:
7.2.2.13
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04022
cGMP-PKG signaling pathway
hgl04024
cAMP signaling pathway
hgl04260
Cardiac muscle contraction
hgl04261
Adrenergic signaling in cardiomyocytes
hgl04820
Cytoskeleton in muscle cells
hgl04911
Insulin secretion
hgl04918
Thyroid hormone synthesis
hgl04919
Thyroid hormone signaling pathway
hgl04925
Aldosterone synthesis and secretion
hgl04960
Aldosterone-regulated sodium reabsorption
hgl04961
Endocrine and other factor-regulated calcium reabsorption
hgl04964
Proximal tubule bicarbonate reclamation
hgl04970
Salivary secretion
hgl04971
Gastric acid secretion
hgl04972
Pancreatic secretion
hgl04973
Carbohydrate digestion and absorption
hgl04974
Protein digestion and absorption
hgl04976
Bile secretion
hgl04978
Mineral absorption
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
101721060 (Atp1a4)
04022 cGMP-PKG signaling pathway
101721060 (Atp1a4)
09140 Cellular Processes
09142 Cell motility
04820 Cytoskeleton in muscle cells
101721060 (Atp1a4)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
101721060 (Atp1a4)
04918 Thyroid hormone synthesis
101721060 (Atp1a4)
04919 Thyroid hormone signaling pathway
101721060 (Atp1a4)
04925 Aldosterone synthesis and secretion
101721060 (Atp1a4)
09153 Circulatory system
04260 Cardiac muscle contraction
101721060 (Atp1a4)
04261 Adrenergic signaling in cardiomyocytes
101721060 (Atp1a4)
09154 Digestive system
04970 Salivary secretion
101721060 (Atp1a4)
04971 Gastric acid secretion
101721060 (Atp1a4)
04972 Pancreatic secretion
101721060 (Atp1a4)
04976 Bile secretion
101721060 (Atp1a4)
04973 Carbohydrate digestion and absorption
101721060 (Atp1a4)
04974 Protein digestion and absorption
101721060 (Atp1a4)
04978 Mineral absorption
101721060 (Atp1a4)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
101721060 (Atp1a4)
04961 Endocrine and other factor-regulated calcium reabsorption
101721060 (Atp1a4)
04964 Proximal tubule bicarbonate reclamation
101721060 (Atp1a4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hgl04147
]
101721060 (Atp1a4)
Enzymes [BR:
hgl01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.13 Na+/K+-exchanging ATPase
101721060 (Atp1a4)
Exosome [BR:
hgl04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
101721060 (Atp1a4)
Exosomal proteins of other body fluids (saliva and urine)
101721060 (Atp1a4)
Exosomal proteins of colorectal cancer cells
101721060 (Atp1a4)
Exosomal proteins of bladder cancer cells
101721060 (Atp1a4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Hydrolase
Cation_ATPase_N
Hydrolase_3
HAD
DUF1290
LiaI-LiaF-TM_PspC
Motif
Other DBs
NCBI-GeneID:
101721060
NCBI-ProteinID:
XP_004858783
UniProt:
A0AAX6PUK2
LinkDB
All DBs
Position
Un
AA seq
1032 aa
AA seq
DB search
MEHVGRRGKVSPHDWHPSRRPKREPKMKKKIKVKRERKKKDIEELKKEVVMNDHKLTLEE
LSAKYSVDLTNGHSPEKAKEILIRDGLNTLTPPRTTPEWVKFCKQLFSGFALLLWIGSIL
CFMAHGIQLYFNEKSTNDNLYLGIVVAVIIGITGCFSYYQEARSSKIMESFKNMVPQQAL
VIXGGKKMQINVQDIVVGDLVEVKAGDRIPADLRLISAQGCKVDNSSLTGESEPQSRTTA
FTHENPLETRNICFFSTNCMEGSAWGVVIATGDSTVMGRIASLASGLKTGQTPIGAEIEH
FIHLITGVAIFLGVTFFVLSLALGYGWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKR
MARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDGTVHNADTSEEQTGDX
KFTKGSDTWFTLAQIAGLCNRADFKADQETLPITKRETTGDASESALLKFVEQCYSSVKE
MREKSPKVAEIPFNSTNKYQLSIQRQEDGSPGHVLMMKGAPERILEFCSSFLLHGQEFPM
DDKMKNAFQDAYSELGSLGERVLGFCFLNLPSSFSTGFPFNTDEINFPMSNLCFVDLISM
IDPSRAAVPSAVSKCRSAGIKVIMVTGGHPTTAKAIARGVGIISEDTETAEDIAARLDIP
VSQVDPSKTKAIVVHGSELKEMNSEQLSQILLSHTEIXFARTSPQQKLIIVEGCQKLGAI
VAVTGDGVNDCPALKKADIGIAMGITGSDVSKQAANMILLDDNFGSIVTGVEEGRLIFDN
LKKSIAYTLTSNIPEITPFLLFIILSIPLPLGTITILCIDLGTDMIPAISLAYESPESDI
MQRHPRNPKTDNLVNHRLIGIAYGQIGMIQALAGFFTYFVVMAENGFTPFHLLGIRLKWD
DQFFNNLEDSYGQQWTYQQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKN
KVLIFGLLEETLLAVFLSYTPGMGVALQMYPLRVTWWLCAIPYSIVIFIYDQVRKLIIRK
RPDSWLERETYY
NT seq
3099 nt
NT seq
+upstream
nt +downstream
nt
atggagcatgtaggaagaagagggaaagtaagtccccacgattggcatccaagccggaga
cccaaaagggagcctaaaatgaagaagaaaataaaggtgaaaagggaaagaaagaagaaa
gacatagaggaactgaagaaggaggtggtcatgaatgatcacaaattgaccttggaagag
ctgagcgccaagtactcagtggacctgacaaatggccacagtcctgaaaaggcaaaggaa
atcctgattcgggatggactcaatacacttacgcctccccgcaccactccagaatgggtc
aaattctgtaaacaactgttcagtggttttgccctccttctgtggattggttccattctc
tgcttcatggcccatggcatccagctatatttcaatgagaaatctaccaatgataatctg
tacctgggcattgttgtggctgtcatcattggcatcactggctgcttctcttattaccag
gaggccaggagttccaagatcatggagtcttttaagaacatggtgccacagcaagccctg
gtaatttgaggaggaaagaagatgcaaattaatgtacaagacatagtggtgggagacctg
gtagaagtgaaggccggagaccgaatccctgctgacctacggcttatctctgcacaaggg
tgtaaggtggacaactcatccttgactggggagtcagagccccaatcccggaccactgct
ttcacccatgagaaccctctggagacaagaaatatctgcttcttctccaccaactgtatg
gaaggatcagcctggggtgttgtgattgcaacaggagactccacagtgatgggccgaatt
gcctcactggcatcaggcctgaaaactggccaaacccccattggtgctgagattgaacac
ttcatccatctgataacaggggtggccatcttccttggtgtcactttttttgtactctct
cttgcgttgggctatggctggctagaggctgtaatttttctcattggcattattgtggcc
aatgtacctgaggggctgctggccaccgtcacggtgtgcctgacgctgacagccaagcgc
atggcgcggaagaactgcctggtgaagaacctggaggcggtggagacgctgggctccacg
tccaccatctgctcggacaagacgggcaccctcacccagaaccgcatgaccgtcgcccat
ttgtggtttgatggaactgtgcacaatgccgacaccagcgaggaacagactggtgactag
aaattcaccaagggctctgatacctggtttaccctggcccagattgcaggtctctgcaac
cgggctgactttaaagctgaccaggagaccttgcccataactaagcgggaaacaacaggg
gatgcttcagagtcagccctcctcaagtttgtcgagcagtgttacagctccgtgaaggag
atgagagagaaaagtcccaaagtggcagagattccctttaattctaccaacaagtaccag
ctgtccatccaacgtcaggaggatggctccccgggccatgtgctgatgatgaagggtgct
ccggagaggatcttggagttctgctcctccttcctcctgcatggccaggagttcccaatg
gatgataaaatgaagaatgccttccaggatgcctactcagagctgggaagtctgggggaa
cgcgtgctagggttctgcttcttaaatcttccaagcagcttctcaacaggattccccttt
aacacagatgaaataaattttcccatgagtaacctgtgttttgtggacctcatatccatg
attgacccttctcgtgctgctgtgccttctgctgtgagcaagtgtcgtagtgcagggatt
aaggtcatcatggtaacagggggtcatcccactacagcaaaggccattgccagaggtgtg
ggcatcatctcagaagacactgagacagcagaggacattgctgcccggcttgacatccct
gtcagccaggttgatcccagtaaaaccaaagccattgtggtgcatggctcagagttaaag
gagatgaactcagagcagctcagccagatcctcctaagccacacggagattnngtttgcc
cgaacctcccctcagcagaagctcatcattgtagagggctgtcagaagttgggagccatt
gtggcggtgacgggggatggggtgaacgactgccctgcgctgaagaaggccgacattggc
attgccatggggatcactggctctgacgtctccaagcaggcggccaacatgatcctgctg
gatgacaactttggctccatcgtcacaggcgtggaggagggtcgcctcatctttgacaac
ctgaagaaatccatcgcctacaccctgaccagcaacattcctgagatcacccccttcctg
ctgttcatcatcctcagcatccccttgcctctgggcaccatcactatcctctgcattgac
ctgggcacagacatgatacctgctatctccttggcttatgagtccccagagagtgacatc
atgcagaggcatccacggaacccaaagactgataatcttgtgaatcaccgtctcattggc
atagcctatggacagattgggatgatccaggctctagctggattcttcacctatttcgtg
gtcatggctgagaatggctttacacctttccatctgctgggcatccgcctgaagtgggat
gatcaattcttcaataacctggaggacagctatgggcagcaatggacctaccagcagcgg
aaggtggtggagttcacgtgccacacagccttctttgtcagcatcgtggtggtgcagtgg
gctgacctcatcatctgcaagacccgccgcaactctgtcttccagcagggcatgaaaaac
aaggtcctaatatttgggctcctggaagagacattactggcggtttttctatcctacaca
ccgggcatgggcgtggccctgcaaatgtacccactcagggtaacctggtggctctgcgcc
attccctacagcattgttatcttcatctacgatcaagtcagaaaactaatcatccgtaaa
cgacctgacagctggctggagagggagacgtactactaa
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