KEGG   Heterocephalus glaber (naked mole-rat): 101721146
Entry
101721146         CDS       T02812                                 
Symbol
Atp1a3
Name
(RefSeq) ATPase Na+/K+ transporting subunit alpha 3
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04022  cGMP-PKG signaling pathway
hgl04024  cAMP signaling pathway
hgl04260  Cardiac muscle contraction
hgl04261  Adrenergic signaling in cardiomyocytes
hgl04820  Cytoskeleton in muscle cells
hgl04911  Insulin secretion
hgl04918  Thyroid hormone synthesis
hgl04919  Thyroid hormone signaling pathway
hgl04925  Aldosterone synthesis and secretion
hgl04960  Aldosterone-regulated sodium reabsorption
hgl04961  Endocrine and other factor-regulated calcium reabsorption
hgl04964  Proximal tubule bicarbonate reclamation
hgl04970  Salivary secretion
hgl04971  Gastric acid secretion
hgl04972  Pancreatic secretion
hgl04973  Carbohydrate digestion and absorption
hgl04974  Protein digestion and absorption
hgl04976  Bile secretion
hgl04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    101721146 (Atp1a3)
   04022 cGMP-PKG signaling pathway
    101721146 (Atp1a3)
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    101721146 (Atp1a3)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    101721146 (Atp1a3)
   04918 Thyroid hormone synthesis
    101721146 (Atp1a3)
   04919 Thyroid hormone signaling pathway
    101721146 (Atp1a3)
   04925 Aldosterone synthesis and secretion
    101721146 (Atp1a3)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    101721146 (Atp1a3)
   04261 Adrenergic signaling in cardiomyocytes
    101721146 (Atp1a3)
  09154 Digestive system
   04970 Salivary secretion
    101721146 (Atp1a3)
   04971 Gastric acid secretion
    101721146 (Atp1a3)
   04972 Pancreatic secretion
    101721146 (Atp1a3)
   04976 Bile secretion
    101721146 (Atp1a3)
   04973 Carbohydrate digestion and absorption
    101721146 (Atp1a3)
   04974 Protein digestion and absorption
    101721146 (Atp1a3)
   04978 Mineral absorption
    101721146 (Atp1a3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101721146 (Atp1a3)
   04961 Endocrine and other factor-regulated calcium reabsorption
    101721146 (Atp1a3)
   04964 Proximal tubule bicarbonate reclamation
    101721146 (Atp1a3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hgl04147]
    101721146 (Atp1a3)
Enzymes [BR:hgl01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     101721146 (Atp1a3)
Exosome [BR:hgl04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101721146 (Atp1a3)
  Exosomal proteins of other body fluids (saliva and urine)
   101721146 (Atp1a3)
  Exosomal proteins of colorectal cancer cells
   101721146 (Atp1a3)
  Exosomal proteins of bladder cancer cells
   101721146 (Atp1a3)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 101721146
NCBI-ProteinID: XP_004873108
UniProt: A0AAX6QHD1
LinkDB
Position
Un
AA seq 1013 aa
MGDKKDDKGSPKKNKGKEHRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQE
ILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSRDNL
YLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDL
IEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCV
EGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILS
LILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGST
STICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNR
AVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL
SIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGE
RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAG
IKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDL
KDFTTEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADI
GVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPF
LLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLI
SMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQ
RKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMRNKILIFGLFEETALAAFLSY
CPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY
NT seq 3042 nt   +upstreamnt  +downstreamnt
atgggggacaagaaagatgacaagggctcgcccaagaaaaacaagggtaaggagcaccgg
gatctggatgacctcaagaaagaggtggctatgacagagcacaagatgtcagtagaagag
gtctgccggaagtacaacacagactgcgtgcagggtctgacacacagcaaagcccaggag
atcctggccagggatggacctaatgcactcacaccgccaccaaccacgccagagtgggtc
aagttctgtcgccagctctttgggggcttctctatcctgctgtggataggggctatcctc
tgtttcctagcctacggcatccaggcaggcactgaggatgacccttctcgtgacaatctg
tacctggggatcgtgctggcggctgtggtgatcatcaccggctgcttctcctactaccag
gaggccaagagctccaagatcatggagtccttcaagaacatggttccccagcaagcccta
gtgatccgggaaggcgagaagatgcaggtgaatgctgaggaggtggtggttggggacctg
atagaaatcaagggtggagaccgagtgccagctgacctgcgcatcatctcagcccacggc
tgcaaggtagacaactcttctctgaccggtgagtccgagccacagacccgctctcctgac
tgcacacatgacaaccccttggagactcggaacatcaccttcttttctaccaactgtgtg
gaaggcactgctcggggcgtggtggtggccacgggtgaccgtactgtcatgggccgcatt
gccaccctggcttcaggcctagaagtgggcaagacacccatcgccatcgagatcgagcac
ttcatccagctcatcactggtgtggctgtctttctgggcgtgtctttcttcatcctctcc
ctcattctgggatacacttggctggaggctgtcattttcctcatcggcatcattgtggcc
aatgtcccagaggggctgctggccactgtcacagtgtgtctgaccctgaccgccaagcgc
atggcccggaagaactgtctggtgaagaatctggaggctgtggagaccctgggctccacg
tctaccatctgctcagacaagacggggaccctcacccagaaccgcatgacggtcgcccac
atgtggtttgacaaccagatccacgaggccgacaccaccgaggatcagtcagggacctcg
ttcgacaagagctcgcacacctgggtggctctgtcccacatcgctggactctgcaaccgt
gccgtcttcaagggcggccaggacaacatccctgtgctcaagagggacgtggctggggac
gcctctgagtctgccctgctcaagtgtatcgagttgtcctctggctctgtgaagctgatg
cgggaacgcaacaagaaagtagctgaaattcccttcaactccaccaacaaataccagcta
tccatccacgagactgaggaccccaatgacaaccgatacctgctggtgatgaagggcgct
cctgaacgcatcctggaccgctgctccaccatcctgctgcagggcaaggagcagccacta
gacgaggagatgaaggaggccttccagaacgcctacctggagctcggcggcctgggcgaa
cgagtgctcggtttctgccattactacctgcctgaggaacagttccccaagggctttgcg
tttgactgtgacgatgtgaacttcaccaccgacaacctctgttttgtgggtctcatgtcc
atgattgaccctccccgagcagccgtccctgatgcagtgggcaagtgtcgcagtgcaggc
atcaaggtcatcatggtcaccggcgatcaccccatcactgccaaggccattgccaagggg
gtgggcatcatctctgagggcaacgagactgtggaggacattgctgcccggctcaacatt
cctgtcagccaggtcaacccccgggatgccaaggcctgtgtgatccacggcactgacctc
aaggacttcaccacagagcaaatcgatgagatcctgcagaatcacacggagatcgtcttt
gcccgcacctccccacaacagaagctcatcattgtggagggctgtcagagacagggagca
attgtggctgtgactggtgatggtgtgaatgactcccctgctctgaagaaggctgacatc
ggggtggccatgggcattgctgggtctgacgtctccaagcaggcagctgacatgattctg
ctggatgataactttgcctctattgtcactggtgtggaggagggccgcctgatcttcgac
aacctgaagaagtccatcgcctacaccctgaccagcaacatccctgagatcacacccttc
ctgctcttcatcatggccaacatcccactgcccctgggcaccatcaccatcctgtgcatc
gacctgggcacggacatggtccctgccatctccctggcctatgaggctgctgagagcgac
atcatgaagagacagcccaggaacccacgcacagacaagctggtcaatgagaggctcatc
agcatggcctatggacagattgggatgatccaggctctcggtggcttcttctcctacttt
gtgatcctggcagaaaatggcttcctgcccggcaacctggtgggcatccggctgaactgg
gacgaccgcactgtcaacgacctggaggacagttatgggcagcagtggacatacgagcag
aggaaagtggtggagttcacgtgccacacggccttctttgtgagcatcgtggtcgtccag
tgggccgacctgatcatctgcaagacccggaggaactcggtcttccagcagggcatgagg
aacaagatcttaatctttggcttgtttgaggagacggccctcgctgcctttctgtcctac
tgccctggcatggacgtggcccttcgcatgtaccctctcaagcccagctggtggttctgt
gccttcccctacagcttcctcattttcgtctacgatgaaatccgcaaactcattctgcgc
aggaaccccgggggttgggtggagaaagaaacctactactga

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