Heterocephalus glaber (naked mole-rat): 101721664 Help Entry 101721664         CDS       T02812                                  Symbol Gck Name (RefSeq) glucokinase   KO K12407   glucokinase [EC:2.7.1.2] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00010   Glycolysis / Gluconeogenesis hgl00052   Galactose metabolism hgl00500   Starch and sucrose metabolism hgl00520   Amino sugar and nucleotide sugar metabolism hgl00524   Neomycin, kanamycin and gentamicin biosynthesis hgl01100   Metabolic pathways hgl01200   Carbon metabolism hgl01250   Biosynthesis of nucleotide sugars hgl04910   Insulin signaling pathway hgl04911   Insulin secretion hgl04917   Prolactin signaling pathway hgl04922   Glucagon signaling pathway hgl04930   Type II diabetes mellitus hgl04950   Maturity onset diabetes of the young hgl05230   Central carbon metabolism in cancer Module hgl_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hgl_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     101721664 (Gck)    00052 Galactose metabolism     101721664 (Gck)    00500 Starch and sucrose metabolism     101721664 (Gck)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     101721664 (Gck)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     101721664 (Gck)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     101721664 (Gck)    04910 Insulin signaling pathway     101721664 (Gck)    04922 Glucagon signaling pathway     101721664 (Gck)    04917 Prolactin signaling pathway     101721664 (Gck)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     101721664 (Gck)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101721664 (Gck)    04950 Maturity onset diabetes of the young     101721664 (Gck) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      101721664 (Gck) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Sec2p Motif Other DBs NCBI-GeneID:  101721664 NCBI-ProteinID:  XP_004839982 UniProt:  G5BIK4 LinkDB All DBs Position Un AA seq 463 aa AA seqDB search MDEARSRVQAALTLAEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTY VRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEM LFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNV VGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNV ELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRMVDESSVNPGQQLYEKLIGGKYMGEL VRLVLLKLVDENLLFHGEASEQLRTRGAFETRFVSQVESDPGDRKQIHNILSTLGLRPSP TDCDLVRRACESVSTRAAHMCSAGLAGVINRMRESRSQDVLRITVGVDGSVYKLHPSFKE QFHSSVRRLAPRCEITFIESEEGSGRGAALVSAVACKKACMLG NT seq 1392 nt NT seq  +upstreamnt  +downstreamnt atggacgaggccaggagcagagtccaggcagccttgacgctggcggagcagatcctggca gagttccagctgcaggaggaggacctgaagaaggtgatgcggcgaatgcagaaggagatg gaccgtggactgcggctggagacccacgaggaggccagcgtgaagatgctgcccacctac gtgcgttccaccccagaaggctcagaagtcggagacttcctgtccctcgacctggggggc accaacttcagggtgatgctggtgaaggtgggggagggggaggagggacaatggagcgtg aagaccaaacaccagatgtactccatccccgaggacgccatgacgggcaccgcagagatg ctcttcgactacatctccgagtgcatctccgacttcctggataagcaccagatgaagcac aagaaactgcccctgggtttcaccttctccttccctgtgaggcacgaggacatcgacaag ggcatcctcctcaactggaccaagggcttcaaagcctcaggagcagaagggaacaacgtc gtggggcttcttcgagacgccatcaagaggagaggggactttgagatggacgtggtggcc atggtgaatgacacagttgccacaatgatctcctgctactatgaagaccaccaatgcgag gtcggcatgattgtggggacgggctgcaatgcttgctacatggaggagatgcagaacgtg gagctggtggaaggggacgagggccgcatgtgcgttaacaccgagtggggcgcctttggg gactctggcgagctggacgagttcctgctggagtacgaccgcatggtggatgagagctcc gtgaaccccggtcagcagctgtacgaaaagctcatcggcgggaagtacatgggcgagctc gtgcggctcgtgctgctcaagctggtggacgagaacctgctgttccacggggaggcctcg gagcagctgcgcacgcgcggagccttcgagacgcgcttcgtgtcgcaagtggagagcgac ccgggtgaccgcaagcagatccacaacatcctgagcaccctggggctccggccctcgccc acggactgcgacctcgtgcgccgcgcctgcgagagcgtgtccacgcgcgctgcgcacatg tgctccgctgggctggcgggcgtcatcaaccgcatgcgcgagagccgcagccaggacgtg ttgcgtatcaccgtgggcgtggacgggtcggtgtacaagctgcaccccagcttcaaggag cagttccactccagcgtgcgcaggctggcgccccgctgcgagataacattcatcgagtct gaggagggcagcggccggggcgccgcgctggtgtccgcggtggcctgcaagaaggcctgc atgctgggctag

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