KEGG   Heterocephalus glaber (naked mole-rat): 101721961
Entry
101721961         CDS       T02812                                 
Symbol
Ndufs8
Name
(RefSeq) NADH:ubiquinone oxidoreductase core subunit S8
  KO
K03941  NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl00190  Oxidative phosphorylation
hgl01100  Metabolic pathways
hgl04714  Thermogenesis
hgl04723  Retrograde endocannabinoid signaling
hgl04932  Non-alcoholic fatty liver disease
hgl05010  Alzheimer disease
hgl05012  Parkinson disease
hgl05014  Amyotrophic lateral sclerosis
hgl05016  Huntington disease
hgl05020  Prion disease
hgl05022  Pathways of neurodegeneration - multiple diseases
hgl05208  Chemical carcinogenesis - reactive oxygen species
hgl05415  Diabetic cardiomyopathy
Module
hgl_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    101721961 (Ndufs8)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    101721961 (Ndufs8)
  09159 Environmental adaptation
   04714 Thermogenesis
    101721961 (Ndufs8)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    101721961 (Ndufs8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101721961 (Ndufs8)
   05012 Parkinson disease
    101721961 (Ndufs8)
   05014 Amyotrophic lateral sclerosis
    101721961 (Ndufs8)
   05016 Huntington disease
    101721961 (Ndufs8)
   05020 Prion disease
    101721961 (Ndufs8)
   05022 Pathways of neurodegeneration - multiple diseases
    101721961 (Ndufs8)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    101721961 (Ndufs8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    101721961 (Ndufs8)
Enzymes [BR:hgl01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     101721961 (Ndufs8)
SSDB
Motif
Pfam: Fer4 Fer4_7 Fer4_16 Fer4_21 Fer4_6 Fer4_10 Fer4_9 Fer4_8 Fer4_2 Fer4_4 Fer4_17 Fer4_3
Other DBs
NCBI-GeneID: 101721961
NCBI-ProteinID: XP_004852261
UniProt: G5BTV7
LinkDB
Position
Un
AA seq 211 aa
MQCLSMPTLLRALTQAVRTGHAASGRSLHSSAVVATYKYVNKREPTMDVKSVTDRAAQTL
LWTELIRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEA
VCPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHE
ELLYNKEKLLNNGDKWEAEIAANIQADYLYR
NT seq 636 nt   +upstreamnt  +downstreamnt
atgcaatgcctgagcatgcccacactgctgcgggccctgacccaggctgtgcgcacaggt
catgctgctagtggccggagcctccatagtagtgccgtggtagcgacctacaagtacgtg
aataagcgggaacccacaatggacgtgaagtcagtgactgaccgggcagctcagaccctg
ttgtggactgagctcatccgaggcctgggcatgaccctgagctacctgttccgggagcca
gccaccatcaactacccgtttgagaagggcccactaagcccacgcttccgtggggagcac
gcactgcgccgttacccatctggggaggagcgctgcatcgcctgcaagctttgtgaggct
gtgtgccctgcccaggccatcaccattgaggctgagcccagggccgatggcagccgccgg
accacccgttacgacattgacatgaccaagtgcatctactgtgggttctgccaggaggcc
tgccctgtggatgccattgttgagggccccaactttgagttctccaccgagacacacgag
gagctgctgtacaataaggagaagctgctgaacaatggggacaagtgggaggctgagatt
gctgccaacatccaggccgactacctctaccggtga

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