Heterocephalus glaber (naked mole-rat): 101724428
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Entry
101724428 CDS
T02812
Symbol
Abl1
Name
(RefSeq) ABL proto-oncogene 1, non-receptor tyrosine kinase
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04012
ErbB signaling pathway
hgl04014
Ras signaling pathway
hgl04110
Cell cycle
hgl04360
Axon guidance
hgl04722
Neurotrophin signaling pathway
hgl05200
Pathways in cancer
hgl05206
MicroRNAs in cancer
hgl05208
Chemical carcinogenesis - reactive oxygen species
hgl05220
Chronic myeloid leukemia
hgl05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101724428 (Abl1)
04014 Ras signaling pathway
101724428 (Abl1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
101724428 (Abl1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
101724428 (Abl1)
09158 Development and regeneration
04360 Axon guidance
101724428 (Abl1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101724428 (Abl1)
05206 MicroRNAs in cancer
101724428 (Abl1)
05208 Chemical carcinogenesis - reactive oxygen species
101724428 (Abl1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
101724428 (Abl1)
09166 Cardiovascular disease
05416 Viral myocarditis
101724428 (Abl1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101724428 (Abl1)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101724428 (Abl1)
Protein kinases [BR:
hgl01001
]
Non-receptor tyrosine kinases
ABL family
101724428 (Abl1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
Motif
Other DBs
NCBI-GeneID:
101724428
NCBI-ProteinID:
XP_004849159
UniProt:
A0AAX6PDT6
LinkDB
All DBs
Position
Un
AA seq
1128 aa
AA seq
DB search
MLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSE
NDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVN
SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS
DGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERT
DITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQ
LLGVCTREPPFYIITEFMTYGNLLDYLRDCNRQEVTAVVLLYMATQISSAMEYLEKKNFI
HRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKS
DVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNP
SDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAASTLLQAPELPTKTRTCRRAAE
HRDAPDVSEMPPTKAQGESEPLDHEPAASPLLPRKERAAPDGGLNEDERLLPKDKKTNLF
SALIKKKKKMAPTPPKRSSSFREMDGQPERRGPAEEDGREASNGAPALPTCDTAEPAKSP
KPSNAAGVPNGAFRELGGSSFRSPHLWKKSGTLTGSRLAASEEEGGGSASKRFLRSCSAS
CVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRASENRPDQAARGTG
TPPPRLVKKAEETADEVFKDATESSPGSSPPSLTPKLLRRQVVMAPPTGLTHKEEAGRGS
ASGTPAAAEPGPPVSRAGTGTPGGPSKAPAEEPRVRRHRHVSESPGRDRGRLSKLKPVPP
PLPASAGKAGKASQSPGQEAAGEAGTKAKALGLAVDAVSSDAAKPSQLVEGLKKSVLPSG
PKLQSATKAPGTPISPVPAPSVLPAASSGLAGDQPSSTAFVPLISTRVSLRKTRQPPERI
ASGAITKGVVLDSTEALCLAISRNSEQMVSHSAVLEAGKNLYTFCVSYVDSIQQMRNKFA
FREAINKLENNLRELQICPATAGGGPAATQDFSKLLSSVKEISDIVQR
NT seq
3387 nt
NT seq
+upstream
nt +downstream
nt
atgttggagatctgcttgaagctggtgggctgcaaatccaagaaggggctgtcctcgtcc
tccagctgctacctggaagaagccctgcagaggccagtagcatctgactttgagccccaa
ggtctgagtgaagctgctcgttggaactccaaggaaaacctccttgccgggcccagtgaa
aatgaccccaaccttttcgttgcactgtatgacttcgtggccagtggtgacaacactcta
agcatcaccaaaggtgaaaagctccgggtcttgggctacaatcacaatggggagtggtgt
gaagcccaaaccaagaacggccaaggatgggtcccgagcaactacatcacacctgtcaac
agcctggagaagcattcctggtaccacgggcctgtgtcccgcaatgccgccgagtacctg
ctgagcagcgggatcaacggcagcttcctggtgcgggagagcgagagcagccctggccag
cgctccatctcactgcgctacgagggccgggtgtaccactacaggatcaacaccgcctcc
gatggcaagctctacgtctcctccgagagccgcttcaacactttggccgagctggttcac
caccattccacggtggccgacgggctcatcaccaccctccactaccccgcgcccaagcgc
aacaagcccacggtctacggtgtgtcccccaactacgacaagtgggagatggagcgcacg
gacatcaccatgaagcacaagctgggtggcggccagtacggggaggtgtacgagggcgtg
tggaagaagtacagcctcaccgtggcggtgaagaccctgaaggaggacaccatggaggtg
gaagagttcttaaaagaggctgcagtgatgaaggagatcaagcaccccaatctggtgcag
ttgctcggggtctgcactcgggagcccccgttctacatcatcaccgagttcatgacctat
gggaaccttctggactacctgcgggattgcaaccggcaggaggtgactgccgtggtgctg
ctctacatggccacgcagatctcctcggccatggagtacctggagaagaagaacttcatc
cacagggatctcgctgcccgaaactgcctggtaggggaaaaccacttggtaaaggtggca
gactttggcctgagcaggctgatgacgggggacacgtacacagcccatgctggagccaag
ttccccatcaagtggaccgcgcccgagagcctggcctacaacaagttctccatcaagtcc
gatgtctgggcgtttggagtactgctttgggaaattgctacctatggcatgtcaccgtac
cccggaattgacctgtcccaggtgtatgagctgctggagaaagactaccgcatggagcgc
ccggaaggctgcccggagaaggtctatgaactcatgcgagcatgttggcagtggaatccc
tctgaccggccgtcctttgctgaaatccaccaggcctttgaaaccatgttccaggagtct
agcatctcggacgaagtggaaaaggagctgggaaagcaaggtgtgcgaggggctgcgagc
accttgctgcaggcccccgagctgcccaccaagacgaggacctgcaggagagcagccgag
cacagagacgcccccgatgtgtctgagatgccccccaccaaggcccagggagagagtgag
cctctggaccacgagcctgccgcgtctccgctgctcccccggaaagagcgagctgctcca
gacggaggcctgaatgaggacgagcgcctccttcccaaagacaaaaagaccaacctgttc
agcgccctgatcaagaagaagaagaaaatggcgccaacccctcctaagcgcagcagctcc
ttccgggagatggacggccagcccgagcgccgggggccggccgaggaggacggccgggaa
gccagcaacggggcgccggccctccccacctgcgacaccgctgagcctgccaagtcgcca
aaacccagcaacgcagctggcgtccccaacggagccttccgggagttggggggctcgagc
ttccgttctccccacctgtggaaaaagtcgggcacgctgactggcagccgcttagcagcc
agtgaggaggagggcggtggcagcgccagcaagcgcttcctgcggtcctgctccgcctct
tgcgtgccgcacggggccaaggacactgagtggcggtcagtcacgctgcctcgggacctg
cagtccaccgggaggcagttcgactcatccaccttcggagggcacaagagtgagaagcca
gccctgcctcggaagcgcgcgagcgagaacaggccagaccaggccgccagaggcaccggg
acgcccccgcccaggctggtgaagaaggccgaggaaaccgccgacgaggtcttcaaggac
gccacagagtccagcccaggctccagtccccccagcctcacccccaagctcctgcgccgg
caggtggtgatggccccacccacgggcctcacccacaaggaagaggccgggaggggcagt
gcctcggggacccctgcagctgctgagccagggcccccagtcagcagggcaggcacaggc
acccctgggggacccagcaaggcccccgctgaggaacccagggtgaggaggcacaggcat
gtgtctgagtccccgggcagggacagggggaggctgtccaagctcaagcccgtgccgcca
cccctgcccgcctctgcggggaaggctgggaaggcctcacagagccccggccaggaggcc
gcaggggaggccggtacaaaagccaaagccttgggtctggctgtggatgccgtgagcagt
gacgctgccaagcccagccagcttgtggagggcctcaaaaagtcggtgctgccttccggg
cccaagctgcagtcggccaccaaggcacccgggacccccattagcccggtacctgctccc
tctgtgctgcctgcagcatcctcgggcctggcaggggaccagccgtcctccaccgccttt
gttcccctcatatccacccgggtgtcactccggaaaacccgccagcccccagagcggatc
gccagcggggccatcacgaagggtgtggtcctggacagcaccgaggcactgtgcctcgcc
atctccaggaactcggagcagatggtcagccacagcgcagtgctggaggccggcaagaac
ctctacacgttctgcgtgagctacgtggattccatccagcagatgagaaacaagtttgcc
ttccgagaggccatcaacaagctggagaacaacctccgggagctgcagatctgcccagcg
actgcagggggtggccccgcggccactcaggacttcagcaagctgctgagctccgtgaag
gagatcagcgacatcgtgcagaggtag
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integrated database retrieval system
