Heterocephalus glaber (naked mole-rat): 101724441
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Entry
101724441 CDS
T02812
Symbol
Ntrk1
Name
(RefSeq) neurotrophic receptor tyrosine kinase 1
KO
K03176
neurotrophic tyrosine kinase receptor type 1 [EC:
2.7.10.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04010
MAPK signaling pathway
hgl04014
Ras signaling pathway
hgl04020
Calcium signaling pathway
hgl04151
PI3K-Akt signaling pathway
hgl04210
Apoptosis
hgl04722
Neurotrophin signaling pathway
hgl04750
Inflammatory mediator regulation of TRP channels
hgl05200
Pathways in cancer
hgl05202
Transcriptional misregulation in cancer
hgl05216
Thyroid cancer
hgl05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101724441 (Ntrk1)
04014 Ras signaling pathway
101724441 (Ntrk1)
04020 Calcium signaling pathway
101724441 (Ntrk1)
04151 PI3K-Akt signaling pathway
101724441 (Ntrk1)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
101724441 (Ntrk1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
101724441 (Ntrk1)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101724441 (Ntrk1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101724441 (Ntrk1)
05202 Transcriptional misregulation in cancer
101724441 (Ntrk1)
05230 Central carbon metabolism in cancer
101724441 (Ntrk1)
09162 Cancer: specific types
05216 Thyroid cancer
101724441 (Ntrk1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101724441 (Ntrk1)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101724441 (Ntrk1)
Protein kinases [BR:
hgl01001
]
Receptor tyrosine kinases (RTK)
TRK family [OT]
101724441 (Ntrk1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
LRRCT_2
I-set
LRR_8
Ig_3
TrkA_TMD
Ig_2
LRR_NXF1-5
LRR_4
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
101724441
NCBI-ProteinID:
XP_004871305
UniProt:
A0AAX6QC09
LinkDB
All DBs
Position
Un
AA seq
798 aa
AA seq
DB search
MLRGGQRGRPRWHRRATALGSLLAWLMLASVGATSCPDVCCPIGPTGLRCTRASPLQSLR
DLPVTENLTELYVENQQHLQHLELRDLQGLGELRNLTIVKSGLRSVAPDAFCSTPQLSRL
NLSFNALESLSWRATRGLSLQELVLSGNPLRCSCALHWLWRWAEEGLGGVRTQGLSCLGP
GNKSLPLGHNTSCGVPMLQVQVSNASVDVGDNVLLRCHVQGRDLQQAGWILSEVEESATV
MKSGDLPSLELTLTNVTRDLNRKNVTCWAENDVGRAEVSVQVNVSFAASVKLVKAVEQHH
WCIPFSVDGQPAPSLRWLFNGSVLNETGFIFTQFLESAPNETARHGCLRLNQPTHVNNGN
YTLLAANPLGQASDSIMAAFMENPFQFNPEDPIPVSFPPVDTNSTSGHPVEKRDDTPFGV
SVAVGLAVFACLFLSALLLVLNKCGQRNKFGINRPAALAPEDGLAMSLHFMTLGGSSLSP
AEGKGSGLQGHIIENPQYFSNTCVHHIKRRDIVLKWELGEGAFGKVFLAECHSLLPEQDK
MLVAVKALKEVSESARQDFHREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLN
RFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLV
GQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLW
EIFTYGQQPWYQLSNAEAIECITQGRELERPRTCPPEVYAIMRGCWQREPQQRCSIKDVH
ARLQALAQAPPVYLDVLG
NT seq
2397 nt
NT seq
+upstream
nt +downstream
nt
atgctgcgaggcggacagcgcgggcggccccgctggcaccgccgagccaccgcgctgggc
agcctgctggcttggctgatgctagcatcggtgggcgccacctcctgcccggatgtctgc
tgccccattggccccaccgggctccgctgcaccagggcttcgcccctacagagcctccgc
gacctgccggtcaccgagaacctgacagaactttatgtggagaaccagcaacatctgcag
catctggagctccgtgacctgcagggcctgggcgaactgagaaacctcaccatcgtgaag
agtggtctccgttccgtggcgccagatgccttctgttccactcctcagctcagtcgcttg
aacctgtccttcaatgctctggagtctctgtcctggagagccacgcggggcctgtcctta
caggagctggtcctgtctgggaatcccctgcgttgctcctgcgccctgcactggctgtgg
cgctgggcggaggaggggctgggcggagtgcgcacacagggcctgagctgcctggggcct
gggaacaagagcctgccactaggccacaacaccagctgcggtgtgcccatgctgcaggtg
caggtgtccaatgcttctgtggatgtgggggacaacgtgctgctgcgttgccatgtgcag
ggccgggacctgcagcaggccggctggatcctctcagaagtggaggagtcggccacggtg
atgaaatctggggatctgccgtccttggagctgaccttgaccaatgtcacccgtgacctc
aacaggaagaacgtgacctgctgggctgagaatgacgtgggccgggctgaggtctccgtc
caggtcaacgtctccttcgccgccagcgtgaagctggtgaaggcggtggagcagcaccac
tggtgcatccccttctccgtggacggccagccggcgccctccctgcgctggctcttcaac
ggctccgtgctcaacgagaccggcttcatcttcacccagttcctggagtcggcgcccaat
gagacggcgcgccacggctgcctgcgcctcaaccagcccacgcacgtcaacaacggcaac
tacacgctgctggccgccaaccccctgggccaggcctccgactccatcatggcggccttc
atggagaaccccttccagttcaaccccgaggaccccatccccgtttccttcccgcccgtg
gacactaacagcacgtctggacacccagtggagaagagagacgacacgcctttcggggtc
tccgtggccgtggggctggctgtctttgcctgcctcttcctgtccgccctgctcctcgtg
cttaacaaatgtggacagagaaacaagttcgggatcaaccgccctgccgcgctggctccg
gaggacgggctggccatgtccctgcatttcatgaccctggggggcagttcgctttcccct
gctgagggcaaaggctctgggctgcaaggccacatcatcgagaacccacagtacttcagc
aacacctgtgtccaccacatcaagcgccgggacatcgtgctcaagtgggagctgggcgag
ggtgccttcgggaaggtcttcctcgccgagtgccacagcctgctgcctgagcaggacaag
atgctggtggccgtcaaggccctgaaggaggtgtccgagagtgcccggcaggacttccat
cgtgaggccgagctgctcaccatgctgcagcaccagcacatcgtgcgcttcttcggggtg
tgcaccgagggccgcccgctgctgatggtctttgagtacatgcggcatggggacctcaat
cgcttcctccggtcccatgggcctgatgccaagctgctggctggcggggaggacgtggct
ccgggtcccctaggcctcggccagctgctggcggtggccagccaggtggcggcaggcatg
gtgtacctggccagcctgcacttcgtgcaccgtgacctggccacacgcaactgtctggtg
ggccagggtctggtggtgaagatcggggactttggcatgagcagggacatctacagcacc
gactactaccgcgtgggaggtcgcaccatgctgcccatccgctggatgccgcccgagagc
attctctaccggaagttcaccactgagagcgatgtgtggagctttggcgtggtgctctgg
gagatcttcacctacggccagcagccctggtaccagctttccaatgccgaggcgatcgag
tgcatcacacagggccgtgagctggagcggccgcgcacctgcccgccagaagtctacgcc
atcatgcggggctgctggcagcgggagccccagcagcgctgcagcatcaaggacgtgcac
gcccggctgcaggcgctggcacaggcacctcccgtctacctggacgtgctgggttag
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