Heterocephalus glaber (naked mole-rat): 101726275
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Entry
101726275 CDS
T02812
Symbol
Ndufv1
Name
(RefSeq) NADH:ubiquinone oxidoreductase core subunit V1
KO
K03942
NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:
7.1.1.2
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00190
Oxidative phosphorylation
hgl01100
Metabolic pathways
hgl04714
Thermogenesis
hgl04723
Retrograde endocannabinoid signaling
hgl04932
Non-alcoholic fatty liver disease
hgl05010
Alzheimer disease
hgl05012
Parkinson disease
hgl05014
Amyotrophic lateral sclerosis
hgl05016
Huntington disease
hgl05020
Prion disease
hgl05022
Pathways of neurodegeneration - multiple diseases
hgl05208
Chemical carcinogenesis - reactive oxygen species
hgl05415
Diabetic cardiomyopathy
Module
hgl_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
101726275 (Ndufv1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
101726275 (Ndufv1)
09159 Environmental adaptation
04714 Thermogenesis
101726275 (Ndufv1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101726275 (Ndufv1)
09164 Neurodegenerative disease
05010 Alzheimer disease
101726275 (Ndufv1)
05012 Parkinson disease
101726275 (Ndufv1)
05014 Amyotrophic lateral sclerosis
101726275 (Ndufv1)
05016 Huntington disease
101726275 (Ndufv1)
05020 Prion disease
101726275 (Ndufv1)
05022 Pathways of neurodegeneration - multiple diseases
101726275 (Ndufv1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101726275 (Ndufv1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101726275 (Ndufv1)
Enzymes [BR:
hgl01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
101726275 (Ndufv1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Complex1_51K
NADH_4Fe-4S
SLBB_2
SLBB
Motif
Other DBs
NCBI-GeneID:
101726275
NCBI-ProteinID:
XP_004852274
UniProt:
G5BTW5
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Position
Un
AA seq
465 aa
AA seq
DB search
MLAARRLLGGSLPARVSSVRFSGDTAAAKKTSFGSLKDEDRIFTNLYGRHDWRLKGAQSR
GDWYKTKEILLKGPDWILGEIKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADE
GEPGTCKDREILRHDPHKLVEGCLIGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEA
GLIGKNACGSGYDFDVFVVRGAGAYICGEETALIESMEGKQGKPRLKPPFPADVGVFGCP
TTVANVETVAVSPTICRRGGTWFASFGRERNSGTKLFNISGHVNHPCTVEEEMSVPLKEL
IEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALVQAQTGLGTAAVIVMDR
STDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVKGDARPAEIDSLWEISKQI
EGHTICALGDGAAWPVQGLIRHFRVELEDRMQRFAQQHQVQQAAS
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atgctggcggcacggcggctgctcggcgggtcgctccccgcgcgagtatcatctgtgcgt
ttcagcggcgacacggcagcggctaaaaaaacctcatttggctcactgaaggatgaagac
cgcatcttcaccaatctatatggccgccatgactggaggctgaaaggtgcccagagtcga
ggtgactggtacaaaacaaaagagattctcctgaaggggcctgactggatcctgggtgag
atcaagacatcaggcttgcggggtcgtgggggtgctggcttccccactggcctcaagtgg
agcttcatgaataagccctcagatggcaggcccaagtatctggtggtgaatgcagatgag
ggggagccaggcacctgcaaggaccgggagatcttgcgccatgatcctcacaagctggtg
gaaggctgcctgatcggtggccgggccatgggtgcccgtgccgcctacatctacatccgt
ggagaattctacaatgaagcctccaatctgcaggtggccatccgagaggcctacgaggca
ggtctgattggcaagaatgcctgtggctctggttacgattttgatgtgttcgtggtgcgt
ggggctggggcctacatctgtggagaggaaacagcactcatcgagtccatggagggcaag
cagggcaaaccacgcctgaagccgcccttcccggctgacgtgggagtgtttggctgcccc
actactgtggccaatgtggagacggtagctgtgtcccccaccatctgccgtcgtgggggt
acctggtttgcaagctttggccgagaacgcaactcgggtaccaaactattcaacatctct
ggccatgtcaaccacccctgcacggtggaagaagagatgtctgtgcccctgaaggagctg
attgagaagcatgctgggggtgtcacaggtggctgggacaacctccttgctgtgatccct
ggtggctcatccaccccactgatccccaagtctgtgtgtgagacggttctgatggacttt
gatgcactggtgcaggcacagacaggcctgggcacggctgcagtgatcgtcatggaccgc
tcgactgacattgtgaaagccattgcccgcctcattgagttctacaagcacgagagctgt
ggccagtgtaccccctgccgcgaaggtgtggattggatgaacaaggtgatggcccgcttc
gtgaagggtgatgcgcggccagctgagatcgactccctgtgggagattagcaagcagata
gagggccacaccatttgtgctctgggcgatggggctgcctggcccgtgcagggtctgatc
cgccacttccgggtagagcttgaagatcggatgcagcggtttgcccagcagcaccaggtc
caacaggctgcctcctga
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