KEGG   Heterocephalus glaber (naked mole-rat): 101726275
Entry
101726275         CDS       T02812                                 
Symbol
Ndufv1
Name
(RefSeq) NADH:ubiquinone oxidoreductase core subunit V1
  KO
K03942  NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl00190  Oxidative phosphorylation
hgl01100  Metabolic pathways
hgl04714  Thermogenesis
hgl04723  Retrograde endocannabinoid signaling
hgl04932  Non-alcoholic fatty liver disease
hgl05010  Alzheimer disease
hgl05012  Parkinson disease
hgl05014  Amyotrophic lateral sclerosis
hgl05016  Huntington disease
hgl05020  Prion disease
hgl05022  Pathways of neurodegeneration - multiple diseases
hgl05208  Chemical carcinogenesis - reactive oxygen species
hgl05415  Diabetic cardiomyopathy
Module
hgl_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    101726275 (Ndufv1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    101726275 (Ndufv1)
  09159 Environmental adaptation
   04714 Thermogenesis
    101726275 (Ndufv1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    101726275 (Ndufv1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101726275 (Ndufv1)
   05012 Parkinson disease
    101726275 (Ndufv1)
   05014 Amyotrophic lateral sclerosis
    101726275 (Ndufv1)
   05016 Huntington disease
    101726275 (Ndufv1)
   05020 Prion disease
    101726275 (Ndufv1)
   05022 Pathways of neurodegeneration - multiple diseases
    101726275 (Ndufv1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    101726275 (Ndufv1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    101726275 (Ndufv1)
Enzymes [BR:hgl01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     101726275 (Ndufv1)
SSDB
Motif
Pfam: Complex1_51K NADH_4Fe-4S SLBB_2 SLBB
Other DBs
NCBI-GeneID: 101726275
NCBI-ProteinID: XP_004852274
UniProt: G5BTW5
LinkDB
Position
Un
AA seq 465 aa
MLAARRLLGGSLPARVSSVRFSGDTAAAKKTSFGSLKDEDRIFTNLYGRHDWRLKGAQSR
GDWYKTKEILLKGPDWILGEIKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADE
GEPGTCKDREILRHDPHKLVEGCLIGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEA
GLIGKNACGSGYDFDVFVVRGAGAYICGEETALIESMEGKQGKPRLKPPFPADVGVFGCP
TTVANVETVAVSPTICRRGGTWFASFGRERNSGTKLFNISGHVNHPCTVEEEMSVPLKEL
IEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALVQAQTGLGTAAVIVMDR
STDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVKGDARPAEIDSLWEISKQI
EGHTICALGDGAAWPVQGLIRHFRVELEDRMQRFAQQHQVQQAAS
NT seq 1398 nt   +upstreamnt  +downstreamnt
atgctggcggcacggcggctgctcggcgggtcgctccccgcgcgagtatcatctgtgcgt
ttcagcggcgacacggcagcggctaaaaaaacctcatttggctcactgaaggatgaagac
cgcatcttcaccaatctatatggccgccatgactggaggctgaaaggtgcccagagtcga
ggtgactggtacaaaacaaaagagattctcctgaaggggcctgactggatcctgggtgag
atcaagacatcaggcttgcggggtcgtgggggtgctggcttccccactggcctcaagtgg
agcttcatgaataagccctcagatggcaggcccaagtatctggtggtgaatgcagatgag
ggggagccaggcacctgcaaggaccgggagatcttgcgccatgatcctcacaagctggtg
gaaggctgcctgatcggtggccgggccatgggtgcccgtgccgcctacatctacatccgt
ggagaattctacaatgaagcctccaatctgcaggtggccatccgagaggcctacgaggca
ggtctgattggcaagaatgcctgtggctctggttacgattttgatgtgttcgtggtgcgt
ggggctggggcctacatctgtggagaggaaacagcactcatcgagtccatggagggcaag
cagggcaaaccacgcctgaagccgcccttcccggctgacgtgggagtgtttggctgcccc
actactgtggccaatgtggagacggtagctgtgtcccccaccatctgccgtcgtgggggt
acctggtttgcaagctttggccgagaacgcaactcgggtaccaaactattcaacatctct
ggccatgtcaaccacccctgcacggtggaagaagagatgtctgtgcccctgaaggagctg
attgagaagcatgctgggggtgtcacaggtggctgggacaacctccttgctgtgatccct
ggtggctcatccaccccactgatccccaagtctgtgtgtgagacggttctgatggacttt
gatgcactggtgcaggcacagacaggcctgggcacggctgcagtgatcgtcatggaccgc
tcgactgacattgtgaaagccattgcccgcctcattgagttctacaagcacgagagctgt
ggccagtgtaccccctgccgcgaaggtgtggattggatgaacaaggtgatggcccgcttc
gtgaagggtgatgcgcggccagctgagatcgactccctgtgggagattagcaagcagata
gagggccacaccatttgtgctctgggcgatggggctgcctggcccgtgcagggtctgatc
cgccacttccgggtagagcttgaagatcggatgcagcggtttgcccagcagcaccaggtc
caacaggctgcctcctga

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