Heterocephalus glaber (naked mole-rat): 101726400
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Entry
101726400 CDS
T02812
Symbol
Kit
Name
(RefSeq) KIT proto-oncogene receptor tyrosine kinase
KO
K05091
proto-oncogene tyrosine-protein kinase Kit [EC:
2.7.10.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04010
MAPK signaling pathway
hgl04014
Ras signaling pathway
hgl04015
Rap1 signaling pathway
hgl04072
Phospholipase D signaling pathway
hgl04151
PI3K-Akt signaling pathway
hgl04640
Hematopoietic cell lineage
hgl04916
Melanogenesis
hgl05200
Pathways in cancer
hgl05221
Acute myeloid leukemia
hgl05224
Breast cancer
hgl05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101726400 (Kit)
04014 Ras signaling pathway
101726400 (Kit)
04015 Rap1 signaling pathway
101726400 (Kit)
04072 Phospholipase D signaling pathway
101726400 (Kit)
04151 PI3K-Akt signaling pathway
101726400 (Kit)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
101726400 (Kit)
09152 Endocrine system
04916 Melanogenesis
101726400 (Kit)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101726400 (Kit)
05230 Central carbon metabolism in cancer
101726400 (Kit)
09162 Cancer: specific types
05221 Acute myeloid leukemia
101726400 (Kit)
05224 Breast cancer
101726400 (Kit)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101726400 (Kit)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hgl04090
]
101726400 (Kit)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101726400 (Kit)
Protein kinases [BR:
hgl01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
101726400 (Kit)
CD molecules [BR:
hgl04090
]
Proteins
101726400 (Kit)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
V-set
C1-set
APH
Motif
Other DBs
NCBI-GeneID:
101726400
NCBI-ProteinID:
XP_012929387
LinkDB
All DBs
Position
Un
AA seq
959 aa
AA seq
DB search
MRGARGAWDFLCVLHLLLRVQPGSSQPSASPGELSPPSILPAQSELIVRAGDQIRLTCTD
PAFVRWTFKTLGDVSENKDSEWIREKAEAAHTGKYTCINRDGLSSSIYVFVRDPAKLFLI
GLPLYGKEDNDTLVRCPLTDPEVTNYSLKECEGKPLPKDLMFVPDPKAGITIRNVKRAYH
RLCLRCTANQEGKLVLSDRFILKVRAAIKAIPVVSVSKPSYLLREGEEFTVTCTIKDVSS
SVGAVWIKENSQLTKAQVKRNSWHRGDFNYERQETLTISSTRVNDSGVFMCYANNTFGSA
NVTTTLKVVDKGFINTFSMMNTTVFVNDGENVDLIVEYEAYPKPEHQQWIYMNRTSTNKW
EDYPKSETESNIRYVSELHLTRLKATEGGTYTFFVSNSDVNASVTFTVYVNTKPEILTYD
RLTNGMLQCVAAGFPEPTIDWYFCPGMEQRCSNSVQPVDVQIQNSSVPPFGKLLVQSSID
SSMFRHNGTVECKASNDVGKISAYFNFAFKEQTHPHTLFTPLLIGFVITAGMMCIIVMVL
TYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKV
VEATAYGLVKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVG
GPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDQAEAALYKNLLHSKESSCSDSTNEYMD
MKPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFL
ASKNCIHRDLAARNILLTHGRITKICDFGLARLPVKWMAPESIFNCVYTFESDVWSYGIF
LWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEIYDIMKTCWDADPLKRPTFK
QIVQLIEKQISDSTNHIYSNLANCTPNPENPVVVDHSVRVNSVGSSASSTQPLLVHEDV
NT seq
2880 nt
NT seq
+upstream
nt +downstream
nt
atgagaggcgctcgcggcgcctgggattttctctgcgtcctgcacctcctgctccgcgtc
cagccaggttcttctcagccatctgcaagtccaggggaactatctcccccatccatcctt
cctgcacaatcagagttaatagtcagagctggtgaccagatcaggctgacatgcaccgat
ccggcctttgtcagatggactttcaagaccctgggtgatgtgagtgagaataaggacagt
gaatggatcagagaaaaagccgaggctgcccacacaggcaaatacacgtgcatcaacaga
gatggcttaagcagctccatttatgtatttgttagagatcctgccaagcttttccttatt
ggccttcccttgtatgggaaagaagacaatgacacactggtccgctgtcctctgacagac
ccagaggtgaccaattattccctcaaggagtgcgaggggaaacctctccccaaggaccta
atgtttgtccccgaccccaaggccggcatcaccatcaggaacgtgaagcgtgcctaccat
cggctctgtttacgttgcactgccaaccaggagggcaagttggtgctgtcggacagattc
atcctgaaagtgagggcagccatcaaagctataccagttgtgtctgtgtccaaacccagc
tatcttctgcgggaaggggaagaatttacagtgacatgcacaataaaagatgtgtctagt
tctgtgggcgcagtgtggataaaggagaacagtcagctaactaaagcacaggtaaaacgt
aatagctggcatcggggtgacttcaattatgaacgtcaggaaacactgactatcagctca
acaagagttaatgattctggagtgttcatgtgttatgccaataatacttttggatcagca
aatgtcacaacaaccttgaaagtagtagataaaggattcattaataccttctccatgatg
aacactactgtatttgtaaatgatggagaaaatgtagatttgattgttgaatatgaggca
taccccaagcctgaacaccagcagtggatatatatgaacaggacctccaccaacaaatgg
gaagattatcccaagtctgagactgaaagtaacatcagatatgtcagcgaacttcatcta
acccggttaaaagcgaccgaaggaggcacttacactttttttgtgtccaactctgatgtc
aatgcttccgtgacatttactgtttacgtgaacacaaaaccagaaatcctgacttatgac
aggctcacgaatggcatgctccagtgtgtggcagcgggattcccagagcccacaatagat
tggtatttttgtccaggaatggagcagagatgttctaattctgtacaaccggtggatgtc
cagattcagaactcctctgtgccaccatttggaaaactcctggttcagagctctatagat
tctagcatgttcaggcacaacggcacagttgagtgtaaggcttccaacgatgtgggcaag
atttctgcctattttaactttgcatttaaagaacaaacccatccccacaccctgttcacc
cctttgctgattggttttgtgatcacagctggtatgatgtgcatcattgtgatggttctc
acctacaaatatttacagaaacccatgtatgaagtgcagtggaaggttgttgaggagata
aatggaaacaattatgtttacatagacccaacacaacttccttatgatcacaaatgggag
tttcccagaaacaggttgagttttggaaagactttgggcgctggcgcctttggtaaagtt
gtggaagccactgcttatggcttagttaaatcagatgcggccatgactgttgctgtcaag
atgctcaagccaagtgcccacttaacagaacgagaggccctcatgtccgaactcaaggtc
ttgagttacctcggaaaccatatgaacattgtgaatctcctgggagcatgcactgtcgga
ggacccaccctggtcattacagaatattgttgctatggtgatcttttgaattttttgaga
aggaaacgtgattcatttatttgctcaaagcaggaagatcaggcagaagcagcactttat
aagaaccttctgcattcaaaggagtcttcctgcagtgacagtaccaatgagtacatggac
atgaagcctggcgtttcttatgttgtcccaaccaaggcagacaaaaggagatcggcaaga
ataggctcatacatagaaagagatgtgactcccgccatcatggaggatgacgagttggct
ctggacctggaagacttgctgagcttttcttaccaggtggcaaagggcatggctttcctt
gcctcgaagaattgtattcacagagacttggcagccagaaatatcctccttactcatggt
cgaatcacaaagatttgtgattttggtctagcccgactgcctgtgaagtggatggcacca
gaaagcattttcaactgcgtgtatacatttgaaagtgatgtctggtcctatgggattttt
ctatgggagctcttctctttaggaagcagcccctaccctggaatgccggttgactccaag
ttctacaagatgatcaaggaagggttccgaatgctcagccccgagcatgcacctgctgaa
atttatgacataatgaagacttgttgggatgctgatcctctaaaaaggccaacattcaag
cagatcgttcagctcattgagaaacagatttcagatagcaccaatcacatttactccaac
ttggccaattgtactcccaacccagagaaccctgtggtggtggatcattctgtgcgggtc
aattcagttggcagcagcgcctcctctacccagcctctccttgtgcatgaagatgtctga
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