Heterocephalus glaber (naked mole-rat): 10201216 Help Entry 10201216          CDS       T02812                                  Symbol COX1 Name (RefSeq) cytochrome c oxidase subunit I   KO K02256   cytochrome c oxidase subunit 1 [EC:7.1.1.9] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00190   Oxidative phosphorylation hgl01100   Metabolic pathways hgl04260   Cardiac muscle contraction hgl04714   Thermogenesis hgl04932   Non-alcoholic fatty liver disease hgl05010   Alzheimer disease hgl05012   Parkinson disease hgl05014   Amyotrophic lateral sclerosis hgl05016   Huntington disease hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05208   Chemical carcinogenesis - reactive oxygen species hgl05415   Diabetic cardiomyopathy Module hgl_M00154   Cytochrome c oxidase Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09102 Energy metabolism    00190 Oxidative phosphorylation     10201216 (COX1)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     10201216 (COX1)   09159 Environmental adaptation    04714 Thermogenesis     10201216 (COX1)  09160 Human Diseases   09161 Cancer: overview    05208 Chemical carcinogenesis - reactive oxygen species     10201216 (COX1)   09164 Neurodegenerative disease    05010 Alzheimer disease     10201216 (COX1)    05012 Parkinson disease     10201216 (COX1)    05014 Amyotrophic lateral sclerosis     10201216 (COX1)    05016 Huntington disease     10201216 (COX1)    05020 Prion disease     10201216 (COX1)    05022 Pathways of neurodegeneration - multiple diseases     10201216 (COX1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     10201216 (COX1)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     10201216 (COX1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03029 Mitochondrial biogenesis [BR:hgl03029]     10201216 (COX1) Enzymes [BR:hgl01000]  7. Translocases   7.1  Catalysing the translocation of protons    7.1.1  Linked to oxidoreductase reactions     7.1.1.9  cytochrome-c oxidase      10201216 (COX1) Mitochondrial biogenesis [BR:hgl03029]  Mitochondrial DNA transcription, translation, and replication factors   Mitochondrial DNA-encoded proteins    Cytochrome c oxidase     10201216 (COX1) SSDB OrthologParalogGFIT Motif Pfam:  COX1 Motif Other DBs NCBI-GeneID:  10201216 NCBI-ProteinID:  YP_004222614 UniProt:  E9NPC9 LinkDB All DBs Position MT AA seq 513 aa AA seqDB search MFINRWLFSTNHKDIGTLYLLFGAWAGMTGTALSILIRTELGQPGTLLGDDQIYNVIVTA HAFIMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQ TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD TRAYFTSATMIIAIPTGVKVFSWLATLHGGDIKWSPAMLWALGFIFLFTVGGLTGIVLAN SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLFSGYTLDPTWAKIQFFVMFIG VNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTLSSMGSLISLTAVMMMVFMIWEAFASKR EVLMTEMTSTNLEWIHGCPPPFHTFEEPTYIKM NT seq 1542 nt NT seq  +upstreamnt  +downstreamnt atgttcattaaccgctgactattttccacaaatcataaagatattggtacgttgtacctg ctatttggggcatgagcaggaataactggaacagccctaagcattctaatccgtactgaa ctagggcaacccggtactctattgggggatgaccagatctacaacgtcatcgtcaccgca catgcattcattataatcttcttcatagttatacccatcataatcggaggattcggaaac tgattggtcccactaataattggagcccctgacatagcattcccacgaataaacaacatg agcttctgacttctacccccctctttcctcctgctcctagcctcatcaatagtagaagcc ggcgccgggacaggatggacggtctaccctcctctagcaggtaacctagcacacgcaggg gcctctgtagacctaacaatcttttcactacacctagcaggtgtatcctcaatcctcggg gcaattaacttcatcactacaatcatcaacataaaaccaccggcaatatcccaataccaa acaccattattcgtctgatccgtactaatcacagcagtacttctcctgttatccctacca gtcctagccgcaggaattacaatactacttaccgaccgaaatctaaacaccacttttttc gaccccgctggaggaggagacccaattctatatcaacatctattctgattcttcggccac ccagaagtgtatatcctaatcctcccaggattcggaatgatttcacatattgttacctat tactcgggaaaaaaagagccattcggttacataggaatagtatgagccataatatccatt ggcttcctgggcttcatcgtctgagcccaccacatattcacagtaggaatagacgtagac acccgagcatactttacatccgcaacaataatcattgcaatccccacaggagtaaaagta ttcagctgactagcaaccctgcacggaggagacatcaaatgatctccagcaatactatga gccttggggttcatcttcctgttcaccgtaggaggtctaactggaattgtcctagcaaac tcctccctagacattgtcctacacgacacgtactacgtagtcgcacacttccattatgtc ttatccataggagccgtattcgccattatagctggctttgttcactgattccccctattc tcagggtacactctcgaccccacatgagctaaaatccaattcttcgtaatatttattgga gtaaatataacattctttccacaacacttcctaggcctatcaggcatgccccgacgatac tccgactacccggacgcctatacaatatgaaacacactgtcctctataggatctcttatt tccctgacagcagtaataatgatagtcttcataatctgagaagctttcgcctcgaaacga gaggtactcataaccgaaataacctccaccaacttagaatgaattcacggctgtcctcca cccttccacacatttgaagaacccacatacatcaaaatataa

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