Heterocephalus glaber (naked mole-rat): 10201219 Help Entry 10201219          CDS       T02812                                  Symbol ND4 Name (RefSeq) NADH dehydrogenase subunit 4   KO K03881   NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00190   Oxidative phosphorylation hgl01100   Metabolic pathways hgl04714   Thermogenesis hgl04723   Retrograde endocannabinoid signaling hgl05010   Alzheimer disease hgl05012   Parkinson disease hgl05014   Amyotrophic lateral sclerosis hgl05016   Huntington disease hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05208   Chemical carcinogenesis - reactive oxygen species hgl05415   Diabetic cardiomyopathy Module hgl_M00142   NADH:ubiquinone oxidoreductase, mitochondria Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09102 Energy metabolism    00190 Oxidative phosphorylation     10201219 (ND4)  09150 Organismal Systems   09156 Nervous system    04723 Retrograde endocannabinoid signaling     10201219 (ND4)   09159 Environmental adaptation    04714 Thermogenesis     10201219 (ND4)  09160 Human Diseases   09161 Cancer: overview    05208 Chemical carcinogenesis - reactive oxygen species     10201219 (ND4)   09164 Neurodegenerative disease    05010 Alzheimer disease     10201219 (ND4)    05012 Parkinson disease     10201219 (ND4)    05014 Amyotrophic lateral sclerosis     10201219 (ND4)    05016 Huntington disease     10201219 (ND4)    05020 Prion disease     10201219 (ND4)    05022 Pathways of neurodegeneration - multiple diseases     10201219 (ND4)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     10201219 (ND4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03029 Mitochondrial biogenesis [BR:hgl03029]     10201219 (ND4) Enzymes [BR:hgl01000]  7. Translocases   7.1  Catalysing the translocation of protons    7.1.1  Linked to oxidoreductase reactions     7.1.1.2  NADH:ubiquinone reductase (H+-translocating)      10201219 (ND4) Mitochondrial biogenesis [BR:hgl03029]  Mitochondrial DNA transcription, translation, and replication factors   Mitochondrial DNA-encoded proteins    Mitochondrial respiratory chain complex I     10201219 (ND4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Proton_antipo_M Oxidored_q5_N Motif Other DBs NCBI-GeneID:  10201219 NCBI-ProteinID:  YP_004222621 UniProt:  E9NPD6 LinkDB All DBs Position MT AA seq 459 aa AA seqDB search MLKIILPTIMLIPVTWLSKNSLLWINTSCHSLLIALISLPTLNKLDINSHNFSTNFFSDS LSSPLVNLTVWLLPLMIIASQHHMKNEPAVRKKLYLSLLITLQALLIMTFTTSEMMMFYI LFEATLIPTLIIITRWGNQAERMKAGLYFLFYTLTGSLPLLVALTYLKNYLGSLNFMLFS YKASPLLPTWSNSMLWLACIMAFMVKFPLYGLHLWLPKAHVEAPIAGSMVLAAILLKLGG YGMMRISQLLEPLTTSMSYPFILLSLWGMVMTSSICLRQTDLKSLIAYSSISHMALVITA ILIQTPWSYMGATTLMIAHGLTSSLLFCLANSNYERTHSRTMILARGLQTILPLMALWWL LASFTNLALPPSINLVGELLIITSTFSWSNFTIILTGMNVLITALYTLYMLISTQRGTPP HHIINLPPSFTRENTLMTLHLLPLLLMTLNPKIIMGNLF NT seq 1378 nt NT seq  +upstreamnt  +downstreamnt atgctaaaaattattctaccaacaatcatactcatcccagtcacctgactatcaaaaaac tcactattatgaatcaacacctcctgccacagcttactcatcgcactaatctccctaccc accctcaacaaactagacattaatagccacaatttctcaacaaacttcttctcagactcc ctgtcatctccactagtaaaccttacagtatgactcctacccctaataatcatcgccagc cagcaccacataaaaaacgaacccgccgtccgaaaaaaactatacctctcactactaatc acactacaggccctacttatcataacatttacaacctcagaaataataatattctacatt ctattcgaagccacactaatcccaactctaattatcatcacccgatggggaaaccaagcg gaacgaataaaggcaggactatatttccttttctacactctcaccggatccctaccactt ctagtagctctaacttacctaaaaaattacctaggctcactgaactttatactattcagc tacaaagcatctccccttttacccacatgatccaacagcatactatgactcgcctgcatc atagcattcatagttaaatttccattatacggcctacacctatgactaccaaaagcccac gtagaagcccccatcgccggctcaatagtactagccgccatcctactgaaactaggaggc tacggaataatacgaatctcgcaactcctagagcccctcacaacctcaatgagctaccca ttcatcttattatccctatgaggaatagttataacgagctccatctgcctacggcaaaca gacctaaaatcccttattgcctactcctccatcagccacatagcccttgtaatcacagct atcctcattcaaacaccatgaagttatataggagccacaaccttaataatcgcccacggc ctcacatcatccctcctattttgcctagcaaactccaactacgaacgcacccatagccga accataatcctagctcgcggactacaaaccatccttcccctaatagcgctctgatgactc ctcgctagctttactaacctcgctttacccccatcaatcaacctagtaggagaactatta atcatcacttcaaccttctcttggtcaaacttcacaatcatcttgaccggaataaacgtg ctcatcacagcactatacacactatacatgctaatttccacacaacgaggcacacctccc caccacatcatcaaccttcccccttcattcacacgagaaaacacactaataacactccac ctactccccctgctactaataaccctcaaccctaaaatcatcatgggaaacctattct

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