KEGG   Halomonas halophila: QWG60_04135
Entry
QWG60_04135       CDS       T09170                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
hhao  Halomonas halophila
Pathway
hhao00290  Valine, leucine and isoleucine biosynthesis
hhao00620  Pyruvate metabolism
hhao01100  Metabolic pathways
hhao01110  Biosynthesis of secondary metabolites
hhao01210  2-Oxocarboxylic acid metabolism
hhao01230  Biosynthesis of amino acids
Module
hhao_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:hhao00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    QWG60_04135 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    QWG60_04135 (leuA)
Enzymes [BR:hhao01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     QWG60_04135 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: WJY08105
LinkDB
Position
906939..908645
AA seq 568 aa
MMLDNPSAKYRPFVAVDLPDRQWPSKRIETPPQWCAVDLRDGNQALIDPMDQERKQRLFD
LLVKIGFKQIEVGFPSASQTDFDFVRSLIEDDKVPEDVTIQVLTQARPHLIDRTFEALKG
ARNAVVHVYNATDPVFRRVVFNVSKPECIQIAVDATTRIREHMTAAPETHWTFQYSPELF
STTEMDFAVEIVDAVEATFGASADKPMIVNLPATVECATPNNYADQVEWFCRHVAKRDHL
IVSVHPHNDRGTGVAAAELAVMAGADRVEGCLFGNGERTGNVDLVTLAMNLYTQGVHPNL
DFSNITPIMREVEYCNQLPVHPRHPYVGDLVFTAFSGSHQDAIKKGMAERREHPDAVWAV
PYLPIDPLDVGRSYEAVIRVNSQSGKGGVSYLLEQEHGIELPRRLSIEFSQVVQEVADRL
GKEITSEMIYQAFVDEYLEQREPFALISHRMSSEPDSPTVTLDATVEEGGERRVIQGQGN
GPLAAFVKALAGEGHDVEIIDYHEHSRGQGADAEAIAYVEVRVNGEAVFGVGTDESITSA
SIKGVLSAINRKHSTEEPAANVTAETLA
NT seq 1707 nt   +upstreamnt  +downstreamnt
atgatgctcgataacccctccgccaagtaccgtcccttcgtggccgtcgacctgcccgac
cgccagtggccgagcaagcgcatcgagacgccgccccagtggtgcgccgtcgacctgcgc
gacggcaaccaggcgctgatcgatcccatggaccaggagcgcaagcagcgcttgttcgac
ctgctggtgaagatcggcttcaagcagatcgaggtgggcttcccctcggcctcccagacc
gacttcgacttcgtgcgttcgctgatcgaagacgacaaggtgccggaagacgtcaccatc
caggtgctcacccaggcgcgcccgcacctgatcgatcgtaccttcgaggcgctcaaggga
gcgaggaacgctgtcgtccacgtctataacgccaccgatccggtgtttcgccgcgtggtg
ttcaacgtcagcaagcccgagtgcatccagatcgcggtggacgccaccacccgcatccgc
gaacacatgacggcggccccggagacccactggaccttccagtactcgccggagctgttc
tccaccaccgagatggacttcgcggtggagatcgtcgatgccgtggaggccaccttcggc
gccagcgccgacaagccgatgatcgtcaatctgccggccaccgtggagtgcgccacgccg
aacaactacgccgaccaggtggagtggttctgccgccacgtcgccaagcgcgatcatctg
atcgtcagcgtgcatccgcacaacgaccgcggcaccggcgtggccgccgccgagctcgcg
gtgatggccggcgccgaccgcgtcgagggctgcctgttcggcaacggcgagcgcaccggc
aacgtcgacctcgtcaccctggccatgaacctctacacccagggcgtgcacccgaacctc
gacttctccaacatcacgccgatcatgcgcgaggtggagtactgcaaccagctgcccgtg
cacccgcgccatccctatgtcggcgatctggtgttcaccgccttctccggctcccaccag
gatgcgatcaagaagggtatggccgagcgtcgtgagcaccccgatgccgtctgggcggtg
ccctacctgccgatcgatccgctcgacgtgggccgcagctacgaggcggtgatccgcgtc
aacagccagtccggcaagggcggcgtctcctatctgctcgagcaggagcacggcatcgag
ctgccgcgccgcctgtcgatcgagttcagccaggtggtgcaggaagtggccgatcggctg
ggcaaggagatcacctccgagatgatctaccaggccttcgtcgacgagtacctcgagcag
cgcgagcccttcgccctgatcagccatcgcatgtcctccgagccggacagccccaccgtg
accctcgacgcgaccgtcgaggaaggcggcgagcgccgcgtcatccagggccagggcaac
ggtccgctggcggccttcgtcaaggcgctggccggcgagggccatgacgtcgagatcatc
gactaccacgagcactcccgcggccagggcgccgatgccgaggcgattgcctacgtggag
gtacgcgtcaacggcgaggcggtgttcggcgtcggcaccgacgagagcatcaccagcgcc
tcgatcaagggcgtactgagcgcgatcaaccgcaagcactccaccgaggagccggcggcc
aacgtgaccgccgaaacgctggcctga

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