Harpia harpyja (harpy eagle): 128134331
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Entry
128134331 CDS
T10541
Symbol
NSD1
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1
KO
K15588
[histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:
2.1.1.357
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00310
Lysine degradation
hhar01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
128134331 (NSD1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hhar03036
]
128134331 (NSD1)
Enzymes [BR:
hhar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.357 [histone H3]-lysine36 N-dimethyltransferase
128134331 (NSD1)
Chromosome and associated proteins [BR:
hhar03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
128134331 (NSD1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PWWP
PHD-1st_NSD
SET
C5HCH
AWS
PHD_NSD
PHD
PHDvar_NSD
PHD_2
MUM1-like_PWWP
Motif
Other DBs
NCBI-GeneID:
128134331
NCBI-ProteinID:
XP_052627914
LinkDB
All DBs
Position
20:10552864..10616292
Genome browser
AA seq
2854 aa
AA seq
DB search
MEQACEVSRRSCLVPFGTSLAAAEAKGGPFGEGRGPEPPAMQLAAAKPVYGQDPSSCYIP
LRRLQDLASMINAEYLGGAADGAEALPDPGSPPPRLPAVQGPAAGADGPGPAADAPRGAL
AFPLFLRDGGEEEAAEEEEEEEEGAETPEEEEDDDDEEEAEEEAAEPGSRSRGRPGPQQG
PASPPPPRLQLAEPVPTTVPDGGPGEKPEPSATAAAAALQLIRAKKKPTPVKYEVGDLVW
AKFNRRPWWPCTICHDPVLDCHSKMKVSNRRPYREYYVDALGEPSEKTWVAGKAIVLFEG
RHQFEELPVLRRRGKQKEKGYKHKVPQRFMAKWEVSVGQAEDILLGGPEDQKCSQNSSEL
DSEKELQSEYYANGPGVERDRQLNGCFKSLAFNSRHPASEKGKLHIKPHVKKSSDSRKRT
RVKKSGARGEASRAEIKEKMPESIVRNMIVGDLPDKHASHELRRIANSLTASSSTRENHL
LSSFGERRFEKTPLKPGYENRKSDALKNTLQGDLFSSASLEREKSSLGILCSSKLQIHYS
ASDAGIEKKQTELDSSSSLSDGGNSDVDTMDQSSERASSALEVSDSSDKVEKEFPMTSSG
NIKLSMYLSQKSNRRARKKSYRDRKPLGGSLTSRLDAEFADRELEVGFSDAEMSLTALER
SSDVRNDNLSLANKHTTPQSVSKDSSWPAVVNQAILKPKSVKLPRIRSIKCKHKEKVAGL
EHSRAEEEGGMNRCSSDTKGFSGLQRDSLQRSGKVDGQKLLNNMHEKPRDSAEIETAVVK
HVLSELKELSYRSMNDDASDSGAPKATVPLLFSSASGHGRLPIEPDYKFSTLLMMLKDMH
DSKTKEQQLMTSQNIVPFRNTSTADGSGSNSTSGLKSLSIVGPPYKIEKNGDCVQETVNP
NSAISNSSFSRNPPTKLTGIGTSKREPASTAVSGTNGTNCVPKRNCSKSKQSSKLGDKTF
SNRKDLKPGGPSKLLSRLSRDSGEHAFRVHGSVTSPLGNEAEDTERKESVALTEHSTDED
SACLSDDNLGRIGRRPEAGRNIESCTSAENGESPDLDSEANSESSLGDESNDINHVAPKK
RWQRFNQSSARSNKHISRSREQGNLESAFGLNSRGFSLKGNECLGRRHSPHSKVLEGDLT
DQDYENHLDLVEKRLNVCGKPNNSVMDSETELGNFAPQSEFSAQVHSERKRLRKPSKRLL
EYAEEYDHLFAPKKKSKKGQEQLQKVNSVVRSDFEGGLPAQCSPDRNTQRGQSPLVSTPS
STKECPPILEAECSFSELGSHSTDPTAQLLEGPSGFPELVLSSSDVSEVSASPDAEERFL
KSGNFESKRQRKPTKKLLESNDLDTAFMPKKEEWTPPKKGTGPSESDSSELYSPAHFSDL
GEASEKLLEKQRKRKRQRHTSAAMHSKKERNEEGLGETPHSEGEISVHGTAASPKEGNEE
GSENDHGVPSSKKMQGERGGGAALKENVCQICEKPGELLLCEAQCCGAFHLQCLGLSEMP
KGKFICNECSTGVHTCFVCKSCGEDVKRCLLPLCGKYYHEACIQKYPPTVMQNKGFRCSL
HICMTCHAANPANISASKGRLMRCVRCPVAYHSNDFCLAAGSVVLASNSIICPNHFTARR
GCRNHEHVNVSWCFVCSEGGSLLCCESCPAAFHRECLNIEMPEGSWYCNDCKAGKKPHYK
EVVWVKVGRYRWWPAEICHPRTIPVNIQKMKHDIGEFPVLFFGSKDYLWTHQARVFPYME
GDVSSKDKMGKGVDGIYKKALQEAAVRFEELKAQKELRQLQEDKKNDKKPPPYKHIKVNR
PVGKVQIFTADLSEIPRCNCKPTDENPCGLDSECINRMLLYECHPLVCPAGERCQNQCFS
KRQYPEVQIFRTLARGWGLQAKTDIRKGEFVNEYVGELIDEEECRARIRYAQEHDITNFY
MLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWCVNGDTRVGLFAIVNIKAGTELTFN
YNLECLGNGKTVCKCGAPNCSGFLGVRPKSQPSLTEEKSKKLKRRPQMKRRSQAEVMKER
EDECFSCGDGGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDMCGKEAASFCEM
CPRSFCKQHREGMLFISKLDGRLCCTEHDPCGPNPLEPGEIREYVPPIGALTNSEDTQPP
EQPPADTDLSVQPLDSLPQSVALRLQSPEKSPATLALKLPPSDKPPTTLALRLQPSNKPP
TTLALRLPPPDKPPATLALRLPPSNKPPTTLSLRLKPSNKPPTTLSLRLQPSDKPPTTLS
LRLQPSDRPQAALSLRLQSEKQPIILALRPQQPDKPPTNAVLWPLDESSSDASQSHLPSK
SPPGTPQSSDESLVTAGALQLQLSDEPPAAPGVLGLSDKSLIDTRTQQPELLDEFPVKCL
HPQLSDRLFTTVGTLQSQPVDEPPVADQPQPFDKASAQSPQLRSVEKAPSSMVPQVPASE
MAPGPGVLWPLPIEKVPGSPVSRILPIEKASGSAVPRPPPPEKASFSRAVRVPAMENAPS
SGVPRLLPPEKAPASGMPRILSTEKAPSLGALRPLPPEKAPGSRSPHILPMEKALGSGAL
RIPLLQKALTPGVLRSLPSEKAADSGALRVLPPEKVLSSGVVRPQLSERSLTLTAPWPQT
SDKLAAAVAPRPQALDKPLAASAPRLLLSEKALRPVDQNAQPKERGAPAVELSPQQKERT
MLAGEQISWSAGKAVTHVGQVPWPMEKLQTHEQTHWPTAKALMPAEQPARTAEKLPEPTL
QPSWEVASAPAEQTPWTSERLRAFEQTPRPAREAPVPPEQMQWLVTNIQTIDQISWLSGK
AQTPRGQDPLPEQNTALARNQDSVCRELADSEPK
NT seq
8565 nt
NT seq
+upstream
nt +downstream
nt
atggagcaggcctgcgaagtgagccgccgcagctgcctcgtccccttcggcacgtcgctg
gcggccgccgaggccaagggcggccccttcggcgagggccgcggccccgagccgcccgcc
atgcagctggccgccgccaagcccgtctacggccaggacccctcgtcctgctacatcccg
ctgcgccggctgcaggacctggcctccatgatcaacgccgagtacctcggcggcgccgcc
gacggcgctgaggccctgcccgaccccggctcgccgcccccccgcctccccgcggtgcag
ggcccggcggccggcgccgacggacccggcccggcggccgacgcgccccgcggggccctg
gccttccccctgttcctgcgggacggcggggaggaggaggcggcggaggaggaggaggag
gaggaggagggcgccgagacgccggaggaggaggaggacgacgacgacgaggaggaggcg
gaggaggaggcggccgagcccggctcgcggagccgcggccgccccggaccgcagcagggc
cccgccagcccgccgccgccccgcttgcagctggccgagccggtgccgacgacggtgccg
gacggcggccccggggagaagccggagccttccgccaccgccgcggcggcggccctgcag
ctcatccgagccaagaagaaacctactccagtgaagtatgaagttggggatcttgtttgg
gccaagttcaacagacgcccatggtggccatgcacaatttgtcatgacccagtgctggac
tgtcactcaaaaatgaaagtttccaatcggagaccataccgagagtactatgtggatgcc
ttaggagaaccttcagagaaaacctgggttgctgggaaagctattgtactctttgaagga
agacatcagtttgaagagctgcctgttcttcggagaagaggaaagcaaaaggaaaaaggc
tacaaacataaggttccccaaagatttatggctaaatgggaagtcagtgttggacaggca
gaagacattcttctcggtgggccagaggatcaaaagtgcagccagaattccagcgagctg
gatagtgagaaggaattgcagtcggaatactatgccaatggccctggagtggaaagggac
aggcagctgaatggctgttttaaatccttggcatttaactccagacacccagccagtgaa
aaaggaaaattgcacattaagccacatgtgaaaaaaagctctgacagcagaaaaaggact
agagtaaaaaagagtggtgcaagaggggaagcatctagggcagaaatcaaagaaaaaatg
ccagagagcatagttagaaacatgattgttggggacctaccagataaacatgcgtctcat
gaacttcgccggattgccaacagcctaacagcatccagtagcaccagggaaaaccatttg
ctttcctcctttggagaaagacgttttgaaaagacacctttgaaaccgggctatgagaat
cgtaaaagtgatgctctgaagaacactctccaaggggatttgttttccagtgcatctttg
gagagagagaagagctccctgggcattttgtgcagttccaaattacaaatacactattct
gcatctgatgctggtattgagaaaaagcaaactgaattggattcatcctcttccctctca
gatggtgggaacagtgatgtagataccatggaccaaagttcagagagagcctctagtgct
cttgaagttagtgattcttcagataaagtggagaaggaatttcctatgacgtcaagtgga
aacattaagctttccatgtatctttctcagaagagcaacagaagggccaggaagaagtca
tacagagatcgcaaacctctgggaggttcactaaccagcaggcttgatgctgaatttgca
gatcgggagctcgaagtaggcttctctgatgctgagatgtcattgacggctcttgagcgc
tcttcggatgtgagaaatgacaatctttccctagcaaacaagcacactactccccaaagt
gtttccaaggacagctcctggcctgctgttgtaaatcaagcaatcttaaaacctaaaagc
gtgaaattgccccgaatcaggagtataaaatgcaaacataaagaaaaagttgctgggttg
gagcattctcgtgcagaagaggagggtggcatgaatcgctgctcttctgataccaaaggt
ttctctggccttcagagagattctcttcagagaagcgggaaagttgatggtcagaaactg
ttaaacaacatgcatgagaaacccagggattctgctgaaatagaaacggctgtggtgaaa
catgtcttgtcagagctgaaggagctgtcttaccggtccatgaatgatgatgctagtgac
tctggcgctccaaaggccacagtacctttacttttctcttccgcctctggtcatggtcgt
ttgcctattgagccagattacaaattcagcaccttgttaatgatgttgaaggatatgcat
gacagtaagacaaaagagcagcaactgatgactagtcaaaatatagtcccatttcgaaat
accagcacagctgatggttctggaagcaattccacgagtggtctgaagtccttgtctatt
gtaggtcccccatataaaatagaaaaaaatggagattgtgtccaggaaacagtaaatcca
aactccgctataagcaactcctcattttcacgcaatcctccaaccaagttgacggggatt
ggtactagtaaaagggagcccgcaagtactgctgtttctgggacaaatggcacaaattgc
gtgcccaaacgcaactgttcaaaatctaagcagtcatcaaagcttggagataaaacattt
tcaaacagaaaggacttaaaaccaggagggccaagtaagttgctaagtcggttatccaga
gattcaggagaacatgcattccgtgttcatggttcggttaccagtcctctaggtaatgaa
gcagaagatactgagaggaaagagtctgttgctttaacagaacattcaactgatgaagac
tctgcctgtttatctgatgacaatttaggtcgtattggaaggagacctgaagctggtaga
aatattgagagctgcacttctgctgaaaatggggagagtccagacttggattcagaggca
aatagtgagagctctcttggtgatgagtctaatgatataaatcacgtagcacccaaaaag
cgatggcagcgttttaaccaaagcagtgctagatctaataagcacatcagtagatctagg
gaacaaggaaacttggagagtgcctttggcctgaattctcgtggcttttcactgaaggga
aatgagtgcttgggacgtaggcattcccctcattcaaaggtgcttgagggagacctgaca
gatcaggactatgagaatcatttagacttagttgagaaacgtttgaatgtatgtggtaag
ccaaacaacagtgtgatggactcagaaacagagcttggcaactttgctccccagtctgaa
ttctctgcacaagtacattcagagaggaaacgccttagaaagccaagtaaacggcttctg
gaatatgcagaagaatatgatcacttatttgcacccaagaaaaaatcaaagaagggccag
gagcaattgcaaaaggtgaattctgtggtgaggtctgattttgaaggaggtcttcctgca
caatgcagtcctgacagaaatacccagcgggggcagagtcctttggtttcaactccatct
tcaaccaaagagtgccctcccatccttgaagcagagtgctccttctcagaactaggatcc
cattccactgatcccactgctcagcttctggaaggaccttcaggttttccagagctggtg
ctgtcttcctcagatgtttctgaagtttctgcttctccagatgcagaagagagattcctg
aaatcaggaaacttcgaaagcaagcgtcagaggaagcccactaaaaagctcttggaatcc
aatgatttggacactgcctttatgccaaagaaggaggagtggactcccccaaagaagggc
actggcccttcagagagtgacagctctgagctctactcaccagcccacttctcggacctg
ggagaagcttctgaaaagctcttggagaagcagcggaagcggaagagacagcgccatacc
tctgctgcaatgcattccaagaaggagagaaatgaggaggggctgggggagaccccacac
tctgagggggagatatcggttcatgggaccgctgcgagccccaaagagggtaatgaagag
gggtcagagaacgaccatggagtgccttcgtccaaaaagatgcagggagagcgtggtgga
ggagcagctctcaaggagaacgtgtgtcagatctgcgagaagccgggagaactgttgctg
tgtgaggcgcagtgctgtggtgctttccacctgcagtgccttgggctctccgagatgcca
aagggcaaattcatctgcaatgagtgttccacaggagtccatacctgctttgtgtgcaag
agctgcggggaagatgtaaaacggtgcttgctgcccctctgtgggaagtattaccatgaa
gcatgcatacaaaagtatccgcccacagtcatgcagaacaagggcttccgatgctccctg
cacatatgcatgacttgtcatgctgctaacccagcaaacatctctgcatctaaaggtcgc
ttgatgcgctgtgtgcggtgtcctgttgcataccactccaacgacttctgccttgctgct
gggtccgtggtccttgcctccaacagcatcatctgccccaatcacttcactgcacggagg
ggctgtcgcaaccatgagcacgtcaacgtcagctggtgctttgtctgctcagaagggggc
agccttttatgctgtgagtcgtgcccggctgcatttcaccgtgagtgtctaaacattgag
atgccagagggaagctggtattgtaatgattgcaaggcaggcaaaaagccacactacaag
gaagtagtctgggtgaaagttgggcgctacaggtggtggccagctgagatttgccatcct
aggacaattcctgtcaacatccagaaaatgaaacatgacatcggtgagttccctgtgctg
ttcttcggctccaaggattacctgtggacgcaccaggcccgtgtgttcccttatatggag
ggtgatgtcagcagcaaagacaagatggggaagggcgtggatggcatatacaagaaagct
cttcaggaagctgcagtaagatttgaagagttgaaggcacagaaagaactgagacagctt
caggaagacaaaaagaacgacaagaaacctcctccctacaaacatatcaaggtgaaccgg
ccagtgggtaaggtgcagatcttcactgcagacttgtccgagataccacgttgcaactgc
aaaccaacagatgaaaacccatgtggcctggattccgaatgcatcaatcgcatgttgctc
tatgaatgccaccccctggtctgccctgctggggagcgctgccagaaccagtgcttctcc
aagcggcagtatcctgaggtacaaattttccgcacgctggcacgaggctggggcttgcaa
gccaaaacagacatcagaaagggtgaatttgttaatgagtatgttggggagctaattgat
gaagaggagtgccgagcccgaatccgctatgctcaggagcatgacatcaccaatttctac
atgttgacactggataaggatcgaatcattgatgctgggccaaagggcaattacgctcgg
ttcatgaaccattgctgccagccaaactgtgagactcagaaatggtgtgtgaatggcgat
actcgggtcgggctcttcgcaattgtaaatatcaaagctgggactgagctgactttcaac
tacaatctggagtgtttgggaaatggaaagactgtttgtaaatgtggtgccccaaattgc
agtggcttcctaggagtacggccaaagagccaacccagcctcactgaggaaaagtccaag
aagctaaagagacggccgcagatgaagcgcaggtcgcaggcggaggtgatgaaggagcga
gaggacgagtgtttcagctgtggggacggagggcagctagtttcttgtaagaagccaggc
tgccccaaggtgtaccacgcagactgcctcaacctgaccaagagacctgcaggaaaatgg
gagtgcccgtggcatcagtgtgatatgtgtggtaaggaagcagcttctttctgcgagatg
tgccccaggtccttctgcaagcagcaccgggaaggcatgctcttcatctccaagctagat
ggacgtttgtgctgcacagagcacgatccttgtgggcctaaccctctagagccaggagaa
attcgtgagtatgtgcctcccataggagccctgactaacagcgaagacacccagccacca
gagcagccgcctgcagacacagacctgagcgttcagcctctggacagcctacctcagtct
gtggccctcagactgcagtcaccagaaaaatcccccgctaccctagcgctgaagctgcca
ccgtcagacaagccccccaccaccctagccttgaggttgcagccatcaaacaagcccccc
accaccctggccctcaggctgcctccaccagacaaaccacccgccaccctggcgctgaga
ctgccaccatcaaataaaccccccactaccttgtcactgaggctgaagccatccaacaaa
ccccccaccaccctctcgctccggctgcagccttcagacaaacctcccacaaccctgtcg
ctccgcctgcagccgtcggacaggccccaggctgccctgtccctaaggctgcagtcagag
aagcaacccatcatcctagcgctgaggcctcagcagcccgacaaacctcccaccaatgcg
gtgctgtggccactggacgagtcctccagtgatgcctcacagtctcatctgccgagcaaa
tctcctccgggaactccacagtcatcagacgagtcgcttgttactgctggtgccctgcag
ctccagctgtcggacgagcctccagccgcccctggggttttggggttatcagacaagtct
ctcattgacaccaggacccagcagcctgagctgctggatgagttcccagtgaaatgcctg
catcctcagctgtcggacagacttttcaccacggtggggaccctgcagtcccagccagtg
gatgagcctcctgtggccgatcagcctcagccattcgacaaagcttctgcccagagtcca
cagcttcggtctgtggaaaaggctcccagctccatggtgccacaggtcccagcatcagag
atggctcctggtcctggggtgctgtggcctctgcccattgaaaaagtccccggctcacca
gtctcgcggatcctgcccatcgagaaggcttctggatcggctgtgccacggccgccacct
ccagagaaggcttccttctccagggcagtgcgggtcccagccatggagaacgctcccagc
tctggggtgccccgtctcctgcctccggagaaggctcctgcctcagggatgccacggatc
ctgtccacagagaaggctcccagcttaggggcgctgcggcccctgcctccggagaaagct
cctggctcccggtcaccgcacatcctgcccatggagaaggctctcggctcaggggccctg
cggatcccactcctgcagaaggcactcacccctggggtgctgcggtccctgccttcagag
aaggctgccgactccggggccctgcgggtcctgcctccggagaaggtgctcagctctggg
gtggttcggcctcagctctcagagaggtctctcactcttacagccccgtggccccagaca
tcggacaagctggctgctgccgtggctcctcggcctcaagccttggacaagcctctggct
gcgtcggctccgaggctgttgctgtcggagaaggcgctgcggcctgttgaccagaatgct
cagccaaaagagagaggagccccagctgtggagctgagtccccagcagaaagagaggacc
atgttagctggtgagcaaatctcttggtctgctgggaaggcggtgacacatgttggacag
gtaccttggcctatggagaaactacagacgcatgagcaaacccactggcccactgcaaaa
gccctgatgcctgcagagcagccagcccggacagcagagaaactaccagagccaaccctt
caacccagctgggaagtggcctcagcccctgcagagcaaaccccttggacatcagagaga
ttgcgtgcatttgagcagacccctcggccagccagggaagcaccggtgcccccagagcag
atgcagtggcttgtcacaaacattcagacaattgaccagatttcttggctgagtggaaaa
gcacagactcctcgggggcaggaccctttgcctgaacaaaacacagcgctagcccgtaac
caggattctgtgtgtcgtgagttggccgactcagagccaaagtga
DBGET
integrated database retrieval system
