Harpia harpyja (harpy eagle): 128137564
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Entry
128137564 CDS
T10541
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00520
Amino sugar and nucleotide sugar metabolism
hhar00541
Biosynthesis of various nucleotide sugars
hhar01100
Metabolic pathways
hhar01250
Biosynthesis of nucleotide sugars
Module
hhar_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
128137564 (GNE)
00541 Biosynthesis of various nucleotide sugars
128137564 (GNE)
Enzymes [BR:
hhar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
128137564 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
128137564 (GNE)
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Gene cluster
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
DRTGG
FGGY_N
Glucokinase
Motif
Other DBs
NCBI-GeneID:
128137564
NCBI-ProteinID:
XP_052634563
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Position
Z:complement(59513463..59546790)
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AA seq
754 aa
AA seq
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MGTNAPPRREPLARGPHEVYFKNLSKQKQKEVMEKNGNNHKLRVCVATCNRADYSKLAPI
MFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVESV
GLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRH
AITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGED
VKTRDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNVDAGSKEMVRVMRKK
GIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQTGRETG
ENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLKEPLQKKFC
FPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYTQLNPKTYEDRLEL
ILKMCVEAASEAVNVNCRILGVGISTGGRVNPREGIVLHSTKLIQEWSSVDLRTPISDAL
HLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGIGGGIIHQHELIHGSSFCAAELG
HIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLLVEGMSMKEEEVVSAAHLI
QAAKLGNTKADSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYVNAVKDVINRQAL
SSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY
NT seq
2265 nt
NT seq
+upstream
nt +downstream
nt
atggggaccaacgcgccgccgcgccgggagccgctcgcccgcggcccccacgaagtgtat
ttcaagaatctttcaaaacagaaacaaaaggaagtaatggagaagaatggaaacaaccac
aaacttcgtgtttgtgttgctacttgcaaccgtgctgattattcaaaattagctcccatt
atgtttggtattaaggcagaaccacagttctttgagcttgatgtcgtagtacttggttcc
cacctgatcgatgattatggtaatacttatcgtatgattgaacaagatgatttcgatatt
catacaagattgcacaccattgtgagaggggaggatgaggcagctatggtggagtcagta
ggccttgcattagtcaagttaccggatgtcctgaaccgcctgaaacctgacataatgata
gttcatggggacagatttgatgctttggccctggccacatctgcagccctgatgaatatt
cgcattcttcacattgaaggtggagaagtcagtgggaccattgatgactctatcagacac
gctataaccaaactggcccattaccatgtgtgctgcacgaggagtgcagagcagcatttg
atagccatgtgtgaagaccatgaccgcatccttctagcaggctgtccctcatatgacaag
cttctctctgccaaaaataaggactacatgagtattatacgcatgtggctaggtgaagat
gtcaaaaccagggattatatagttgctcttcaacatcctgtaaccacagatattaaacat
tccataaagatgtttgagctgacactagatgcactcatctccttcaacaagagaacactt
gttctattccctaatgtggatgcaggaagcaaagagatggttcgggtgatgaggaagaag
ggcattgaacatcatcccaattttcgggcagtaaagcatgtcccatttgaccagttcatt
cagctagttgctcatgctggttgtatgattggtaacagcagttgtggtgtcagagaggtg
ggagcatttggtacacctgtcattaacttggggacacgtcagacaggaagagaaacaggt
gaaaatgtacttcatgttcgtgatgctgatacacaggacaagattctgcatgctctacag
ctgcagtttggtaaacagtatccttgctcaaaaatatatggagatggtaatgctgttcca
aggattttgaagttccttaaatctattgacctcaaagagccattgcaaaagaaattctgt
tttcctcctgtcaaagataatatttctcaagatattgaccatattctagagacacagagt
gctctggctgtggatctaggtggaacaaatctccgagtagcaattgtcagtatgaagggt
gaaatagttaagaagtatacccagctcaaccctaaaacttatgaagacagactagaatta
attctaaagatgtgtgtagaggctgcgtcagaggcagtaaatgtgaactgcagaattttg
ggagtaggtatttccacaggtggacgggtaaatccccgagaaggaattgtgcttcactct
acaaaactcattcaggagtggagctctgtggatctcagaactccaatatctgatgctctg
cacctgccagtctgggtggacaatgatggaaactgtgctgcactagcagagaggaaattt
ggtcatggaaaaggaatagaaaattttgtaacactcattactggtacaggaattggaggt
ggaatcattcatcaacacgaattgatccatggcagttctttctgtgctgctgagcttggg
catattgttgtatctttagatggaccagagtgcctgtgtggtagccaaggatgtatagaa
gcgtatgcctctggaatagcattacagagagaagctaagaaactgcatgatgaggatctg
cttttagtagaaggaatgtcaatgaaggaggaggaggttgttagcgctgcacatctcatt
caagcagctaaacttgggaacacaaaagcagacagcattctcagaacagctgggacagca
ttaggccttggagttgtgaacattctgcacaccatgaacccctctcttgttatcctttct
ggagttctagctagccactatgttaatgctgtcaaagatgtgataaatcgacaggctctg
tcctctgttaaaactgtggatgtggtggtctcaaatctagcagatcctgctcttcttgga
gctgctagcctggttctggattatactacacgtagaatatactag
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