Harpia harpyja (harpy eagle): 128139313 Help Entry 128139313         CDS       T10541                                  Symbol MDN1 Name (RefSeq) midasin isoform X1   KO K14572   midasin Organism hhar  Harpia harpyja (harpy eagle) Pathway hhar03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:hhar00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     128139313 (MDN1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:hhar03009]     128139313 (MDN1) Ribosome biogenesis [BR:hhar03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     128139313 (MDN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_3 AAA_16 AAA_7 AAA_22 nSTAND3 TsaE Sigma54_activ_2 AAA_18 AAA_14 ABC_tran AAA_6 Dynein_heavy MDN1_4th AAA_25 bpMoxR DUF815 PduV-EutP AAA_23 Motif Other DBs NCBI-GeneID:  128139313 NCBI-ProteinID:  XP_052637471 LinkDB All DBs Position 3:19445130..19551958 Genome browser AA seq 5573 aa AA seqDB search MADLRFPLAEPLQLVARRNEKSSAELSRFLAKQIWTQQDRQCILDTLAQLLLDKECTLLI GRQVRPILLDLLERNAEAIKTGGQINHDRHERLCVAMSKLVADHPDVLPFALRYFKNTSP VFQRLFLESSDSNTVRYGRRRMKLRDLMEAAYRFLQKEQSVFRELWDWSVCIPLLRSHDT LVRWYTSNCLALVTCMNDEHKLSFLKKMFNPEELIHFRLKLLEESRLQNVEQALVLANPD SSFWQKEKELQYTQGHIVLGDLSANVVAVCGIVLPRLQLVSEEEEKSTSRFVLVESAFTN LQNLAIAVAYQSPVLLEGPIGCGKTSLIEYLAAVTGRAKPPHILKVQLGDQTDSKTLLGM YRCTDVPGEFVWQPGTLTQAVTKGHWILLEDIDYAPLDVISVLIPLLEKRELLIPGRGDC LKVASGFQFFATRRLFSCGGGWYRQQSSHAALLDKYWTKIHLDNMSKGELKEVLQRRYPN LALVTDHLLDIYIHVTGDKYQASENSASGSRHTPEDSSESRSENKKPNLEGRELSLRDLL NWCSRIAYNFDSNSSTTAVNIFQEALDCFTAMLSNQGSRQKMAKVIGSKLNISKKKVEFF CELYKPEILIREQEVSVGRVHLMKKQTQALTVQRAKQTFAATRPSAVLIEQLAVCVVKGE PVLLVGETGTGKTSTVQYLAHITGHHLRVINMNQQSDTADLLGGYKPVDNKLIWLPLRES FEELFSQTFSRKKNQTFLGHIQTCYRQKRWHDLLKLMQHIHKSAINKEAKENASGLPLKE KWEAFGLKLNHAHQQMKMTENALLFAFVEGTLAQAVKKGEWILLDEINLAAAETLECLSG LLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKKNLPPGIRNRFTELYVEELR NEGDLQVLIMDYLRGLNVNKNTVQGIVNFYLSVRKEAETKLVDGTGHRPHYSLRTLCRAL RFAASNPCSSIPRSLYEGFCLSFLTQLDRGSHPVVQKLICQHIVSGNIKSLLKQQIPKPQ AGRFILIEGYWISAGDREPNVDETYVLTPSVKLNLKDIARVVSAGTHPVLIQGETSVGKT SLICWLAAATGNHCVRINNHEHTDIQEYIGCYTSDASGKLVFKEGILIDAMRRGYWIVLD ELNLAPTDVLEALNRLLDDNRELFITETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAF RNRFVELHFDELPSAELETILHKRCSLPPSYCSKLVKVMLDLQSYRRGSTVFAGKHGFIT LRDLFRWAERYRLAEQLEKEYDWLQHLANDGFMLLAGRVRKQEEVDVIQSVLEKHFKKKL YPESLFSGESVKKLLAKSSMQMSVMDRDFKHIVWTQGMRRLAILVGRALEFGEPVLLVGD TGCGKTTICQIFAALTNQKLYSVNCHLHMETSDFLGGLRPVRQRSKDQEESDGSRLFEWC DGPLVLAMKEEGFFLLDEISLADDSVLERLNSVLEAEKTLVLAEKGGQDDEENEVELLVA GKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSNGRDDLIQIVKHNLHPGLSLGGI NHQGADIAELMMDFVEWLTNQEFGRQCILSVRDVLSWVNFMNVTVEDEESNSAKEYSLLY ISPMMSFIHAACLVYIDGIGSGTTSCSADMALLAREKCLTFLCEKMSQFLELTDYQKNEL KIYDRTKEKEFVWMDNFMGIHPFFIPRGPVLQRNSITDYALNAGTTAVNAQRLLRALQLN KPILLEGSPGVGKTSLVAALAKASGNCLVRINLSEQTDVTDLFGTDLPVEGGKGGEFAWR DGPLLAALKAGHWIVLDELNLASQSVLEGLNACFDHRAEIYVPELGMNFHVQHKMTKIFG CQNPYRQGGGRKGLPKSFLNRFTQVYVDPLSAEDMEFIGNTLFPAIDKSIIAKMVAFNNK IDKEIMAEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGERMRTRED KEKVISIFRDIFGQEADVYTGTREFHITPYNVQIGYSVLSRGNYIPRPGRNLSLLHHSLQ SLESIMKCVHMSWMVILVGPAAVGKTSLVELLAHLTGHRLKIMAMNSAMDTTELLGGFEQ VDINRPWQCLLEKVENAVSTLVRDSLLLTEICADDAELVLRAWSSFILNYKPKSLGEGSR SVTAELVSKLEGILVLTQRLNNKINSYSKAEFAHLVEEFRRFKLQQAQTADRNSHGTFEW VDGMLVQALQSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTMSERGVIDGTIPTIAPHP NFRLFLSMDPVHGEISRAMRNRGIEIYIPGENDGNVLDDLDLKLLLHGLGLVGDSICDAL MAVHSEITTAIAGSVSSLSPLLQAAVLIVQQIQRGLGLAKSFYRACWEVYGRSQQLQINQ KLVLELVTKHASSLASHETWGDSLLAIGLWPDSLPTGLFAAEDSLLSTVQSDAQVLTYCL NRLNLKNCRTLPLTLQDLQKIMQSTNSESLKFSAVEIDADWMDKMEVLQASVKLFIEKAT NQDWTLRVKWLNSFAKNLPQVLDPVWIQLEAGAVALGSFYASPLSSGVSNMIKLLQPTMT DEHVMPLDPRWNMQFLDIIRNSMNFDTEMEHTDQLLILLKSVANRAVLFLDREKRSYTEK NLITSKKPRNSVLRMSLDFRKDPGSYNCLPHAIVVNLAAFFELWDAFAFHWVKSTQVALS DDDMHDILYCLLWRDRFWAVSDTLTVDSPGLSLLSLHWHWVMKHLIDRIPQMLIGSDQHK VSKEIQSVSQQIQNCLANPAVFSASMKILQKSLGRPLPFKDKLGMECFSQLKVLSKPLNI LELRLAFGESRWQEKMCCLKIAATGWKMKKALLQADGLIIRANHLEDVSLGQLKIFLKAV HSQLRAEGVTYSYSEERFTEDTISNQLDPALLNQLCSRVQLWPAMEYISMLWQYKLTADY VAKACPRRENCSQELSVCSDLVQLIAFSLKLTPAASHQLSGLWHLLHLNEISPEEMSILS SQLINAALASFWSSTFTTDPDYWLTWRPLPATEEKNFSKSHMNCSVKGPGILTRAVFSKC FFEILTSSSKTSQWDVSGLPVLSSSHVTLGEWMERAQQLHEVSTALWTNLAVSSIADFRY TDARLQGIMLGRQLSALVDLVPMDFQEKFLACCEKLYLKDPVAYEYLFKILRSITDQELL PKEFLFLLLTCLQQFFGEGLKELPETAWRGSLWVNIGLVQIQVWLPQTRFDPAVKREYKL KYAEEELHQLECEWKTNDFSSQLHTGKSIEDEAISNYIHPHLRLLRERMQRLKEQISSLS RKKAFRPPAPPYDCLYQEAHQYINSIAQVSSVQDLLARLLQFLRGERPKSLQAIQNLLNE EASWQQSHHQFRRHLAEEYAVFPDAIIPLQAAILQLQHGMRLVASEVYTVLKSFVRPADL TNLLTSLLTFPSVGHAFPTYLARAEILCSVNSVEVLHGLKKFSLKHSEVESEGVEQPCPT LEQLLVNALLHLRCHVLSRGEMDKKSLQLFRHLCQAIINEWDEQERRAQEREAMERSLYR YRSKSHGKGRSEEEEEEEFRRRFPLHEEDFEDITAQPSLEEKMETKDLLEDQLEVDRALL SKSSMQTVMMVHQELCLNFARSLWYQQSQPSHQAKHYFSTFISCYQTGACLVSQFYPLIG AEMNDSLLGSQLLVSTLLHNTFFEELTSDLVLQQDGPYDFYQHPNVQQVRQCQPVLDNFA KEVNGLLQEWPEHPVLVQLLVVMDRIRSFPLSSPLSKFLNGLEILLAKAQDWEENASRAL SLRKHLDLVTQLIIQWRRLELNCWSVSLDNIMKQHVEKSTKHWFSIYQMIETYVQEQTEA NTEETEQMDLKTLVSMLQAFIEGSTLGEFHARLQALLVFHCHVLLMPQVAEKDVLCSILW NLYNYYKQFSECVEARITELRQPIEKELKEFVKISKWNDVSFWAIKQSVEKIRRTLFKFM KKFEAVLDEPCQPALVEIGKEEQLDCLQKQEESENKETKVQRLNNTLRKILSARTDVAKR LLPEECQDGITFHTESLQYRLPKLTKKMKKMCTTVTENSSFLSLVEDLDQFTGGIIVSVA ELQNLTFDQTADKEKQKSEAKHIQMQKQRALSDLFKSLAKTGLSYRKGLAWSRSKDYHEI LYLRPLDLRSALGVRNCTHEPDATLLTEISSAWDGCQKYFYRSLARHSRLQTALLAPAKD IGLGSIERCKGFTAHLMQMLVRQRRCLTALTEQWILLRNLLSCIQEIDSRLTADREYNVA FPPQDSLQCWTDKLQQLSMQCVMVLEELSWFIQCCPKEELTKCSDNERTDVKTNIFQSSG PEMGNVFTGIPDLIPSELKYLTPITIEQLPPGCRMRNKDQLWLQVATQLNAMLANVKAMK AEVDNIRQQSCETLVYSWRDFEVCTSAMSCLLEVSAQLQDIESLFLPNGEGRQAVNQMAL IKSLKYIQEEVNNTSADFIAWRTQLLDSMSNCSEGNQQSDEEFVAHFSAKVETVIRVVLY AIQCLVERKQEDGKEEDKSLEESEDATSFDLIKAGHITKLLDEDLSADLDSLHVQKAILA VSELLENLKSYGEDYTSNKHKFFNQFCYLLVRLKPMLCRYSDLILFYLTVSLASHRSTGK LLSVLTSIFTELAQKGFCLPKELLEDEAGEGATQFHDYEDGGIGDGEGKKDVSNKIESED QAKDSFQKGEEKEKEDQDSKPDIEGEDNAIEMSEDFEGKMHDGEQEKKENDENSDEEEEL DKQMGNLDNAEADDKLDERLWGDEDDDDDEDASSKTEETGPGMDEEDSELVAKDDNSGTG NKDNKKQPPKDEEKEQQEDDSGNEEKIHEQIDECEYDENEVDPYHGQQEKQPEVEPLDLP DNLNLENDEKSDEEEEDEEEENAFEVDEKPVDLSEAEKMEEPNDENTGETERDDQDAEPA EEGISEDKEEKEDEGDKNADDQEENAGDTEDAAAEEEEESPPPDEEKNESAEDKGIPAAD QGLQPQEEEGKDNSEMDEQLPEPEERMEHETQGQTGQENLQSDSAVELAGEASERDQSKE EYGSGASSANQSEGHESTRMARMASQKQSRKNTQSFKRKPGQADNERSMGDHNEHIHKRL RTIESSSEAKQNTTQPKQNAEEADAFEHIKQGSESYDAQTYDVASKEQEKPIMPLEEKEE GDSEDAAMETEMQSNEDLRAVDTEELKPEKKKSTATKTPGPGEVEPEIQTFDSEDVNDST KEKLPTVTEEKPERSKDSTIHTAHQFVMDTPQHIVRDPEELRKELERHLEVWQTQQSGTP DEEKEAAQLWQRYLVLTAPLSQQLCEQLRLILEPTQAAKLKGDYRTGKRLNMRKVIPYIA SQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMIDNHSKQLAYESLAVIGNALTLLEVGQI AVCSFGETVQLLHPFHEQFSDQSGTRILRLCKFQQKKTKIAQFLESSANMFAAAQQLSQN INPETAQLLLIVSDGRGLFLEGKERVTAAVQAAQNANIFVIFVVLDNPNSRDSILDIKVP IFKGPGELPEIRSYMEEFPFPFYMILRDVNALPETLSDALRQWFELVTASDTL NT seq 16722 nt NT seq  +upstreamnt  +downstreamnt atggccgacctgcggttccccctggcggagccgctgcagctggtggcgcgcaggaacgag aagagcagcgcggagctgagcaggttcctggcgaagcagatttggactcagcaggatcgg caatgcatcctcgatactttagcgcagttattactagataaagaatgtactctattgatt ggccgtcaagttcggccaatcttgttggatttgttggaaagaaatgcagaagccattaaa actggtggccaaatcaaccatgatcggcatgaaaggctgtgtgtagcaatgagcaagctg gttgctgaccaccctgatgttttgccatttgctttaagatattttaagaatacatcacca gttttccagaggcttttcctggagagctcggattcaaacacagtccgatatgggcgcaga cgaatgaagttacgggacctcatggaggcagcctatagatttttacaaaaggagcaatca gttttccgggaattatgggactggagtgtgtgtattccactcctaaggagtcatgacact ttagtccgttggtatacttcaaactgtcttgctctggttacatgcatgaatgatgagcat aaattatctttcctgaagaagatgttcaatcctgaagagctgatacatttcagactaaag ctactagaagaatctcggctgcagaatgtggaacaagcccttgttttggccaatccggac tcctcattttggcaaaaggagaaagaactgcagtatacgcaaggacatattgtattgggc gacctctctgcaaatgtagtagctgtatgtggtattgtgctgcctagactacagcttgtt tctgaagaggaggaaaagagcaccagccgttttgttttggttgaatctgccttcacaaat cttcaaaaccttgctattgctgtagcatatcagagtcctgttttattagaaggaccaata ggatgtggcaaaacttctttaattgaatatttagcagctgttacaggaagagcaaagcct cctcatattttgaaagtccagcttggggatcaaactgatagtaagacactgcttggtatg tatcgttgtaccgatgtaccaggggagtttgtgtggcaacctggaaccttgacacaagcc gttaccaaaggtcattggatacttctggaggatattgattatgctcctctggatgtgatc tctgtgctgattcctcttttggaaaaaagagagttgctgattcctggtcgtggtgactgt ttaaaagtagcgtcgggattccagttttttgcaaccaggaggttatttagttgtggtggc ggttggtacaggcagcaaagcagccacgctgctcttctggacaaatattggaccaaaata catctggataacatgagcaaaggagaactcaaggaggttcttcaaaggagataccccaac cttgctcttgtaactgatcacttgctagacatttacattcacgttacaggagacaagtat caggcatcagaaaacagtgcttctggctccaggcacacaccagaagattcatcagaatca agatcagaaaataagaaaccaaatctggaaggacgagaactctctctaagagacttactg aactggtgcagcaggattgcttacaacttcgacagtaattcttcaaccacagcagtgaat atttttcaggaggcattggactgtttcacagctatgctgtccaaccaagggagcagacag aaaatggcaaaagttattggaagtaaactaaacatttccaagaaaaaggtagagttcttc tgtgaactctataaaccagaaattctgatacgggaacaagaagtttctgtcggaagagtg catctcatgaagaaacaaacccaggctctcactgtacaaagagcaaaacaaacctttgct gccacacggccgtctgcagtattgattgaacagcttgcagtgtgtgttgtcaaaggagag cctgtgcttttggttggtgaaacaggaactggcaaaacctcaactgttcagtaccttgct catattacaggacaccatttgagggttatcaacatgaaccaacaaagtgacacagcagat ctgttagggggttataagcctgtagataacaagctcatctggctacctctgcgagagtct tttgaagaactcttctctcagacattctctaggaagaaaaatcagacattcttgggacac attcagacctgctacaggcagaaacgttggcatgatctgctgaaactaatgcaacatatt cataaatctgctattaataaggaagcaaaagaaaatgcatctggcttaccactgaaggaa aagtgggaggcatttggtcttaaactgaatcatgctcatcaacagatgaaaatgacggaa aatgctcttctctttgcatttgttgagggtactctggcacaagcagtaaaaaaaggagag tggattttattggatgagattaacttggctgcagcagagactttagagtgcctgagtggt ttattggaaggatcatctgggtcgctggtgttactagacagaggagacacagagcctctt gtccgtcaccctgattttcgcttgtttgcatgcatgaatccagctacagatgttggaaag aaaaatcttcctccaggaataagaaacaggtttactgaactttatgtagaagaactgaga aatgaaggggacttgcaagttcttatcatggattatctgagaggcttgaatgtgaacaaa aatacagtacaaggaattgtgaacttttatttatctgtgagaaaggaagcagaaacaaag ctggtggatggaactggccacagacctcactatagtctccgtacactttgcagggcattg agatttgcagcgtctaatccatgtagcagcataccacgctcactgtatgagggcttctgt ttgagtttcctgacacagcttgacagaggttctcacccagtagttcaaaagctaatatgc cagcatatagtctctggcaacatcaaaagccttctcaagcagcaaataccaaaaccccaa gcagggagatttatacttatagagggatactggatttcagctggggatagagaacctaat gtagatgagacttatgtgctaaccccttcagtcaagcttaatctgaaagacattgccaga gttgtgtctgcagggactcatccagtactgattcaaggagagacctctgttggtaaaacc agtttaatttgctggttggctgctgctactgggaatcattgtgtaaggattaacaatcat gagcatactgacatccaggaatatattggctgttatacatcggatgcctctgggaagttg gtatttaaggaaggcattctcatagatgcaatgagaagaggttactggattgttctagat gaattgaatttggctcccactgatgttctggaggctctcaaccgtttgttggatgataac agggagctgttcattactgagacccaggaagttgtcaaagctcaccctcgcttcatgctg tttgctacgcagaatcctccagggctttatggtggcagaaaggttttgtccagagccttc agaaatcgttttgtggaactgcattttgatgaactgccaagtgctgaactggaaaccatc ctgcacaagcgatgcagtttgccaccttcttattgcagcaagcttgtcaaagtcatgtta gacctgcaatcttaccgcagaggttcgacagtgtttgctgggaagcatgggttcattacc ctgcgggatctgtttcgttgggctgaaaggtacagattggcagaacagctggagaaggag tatgactggcttcagcacttagcaaatgacggttttatgcttctggcaggcagagtcagg aaacaggaggaggtggatgttattcagagcgtccttgaaaaacacttcaagaagaaacta tatccagagtccctcttctcaggggaaagtgtcaaaaagctactggctaaatcctccatg cagatgtcggtgatggacagagattttaagcatattgtctggactcaagggatgaggaga cttgccattttggtgggacgagccctggagtttggtgaaccagtactgctggtgggagac actgggtgtggtaaaactaccatttgtcagatctttgcagcattaacaaatcagaagcta tactcagtaaattgccacttgcatatggagacttcagacttcctgggaggactgcgacca gtcagacagaggtcaaaagaccaggaggaatctgatggttctagactctttgagtggtgt gatggacctcttgttttagcaatgaaagaggaggggtttttcctcctcgatgagatttct ttagctgatgattctgtactagagcgacttaacagtgttcttgaagctgaaaagacattg gtacttgctgaaaaaggtggtcaagatgatgaggagaacgaggtagaactattagttgca ggaaagaaatttcgtatccttgcaaccatgaacccaggaggtgactttgggaaaaaagag ctttctcctgcattgcgcaacagatttacagaaatatggtgtccacaaagcaatggccgt gatgatttgatacagattgtaaaacacaatcttcatccaggattgtctctgggtggaata aaccatcaaggggctgacatagcagagctcatgatggactttgttgaatggctgactaat caagagtttggtcgccagtgcattctcagtgtgcgagatgtcttgtcatgggttaatttt atgaatgtcacggtagaggatgaagagtcgaattctgccaaagaatatagccttctttac atttctccaatgatgtcttttatccatgctgcatgtttggtatacattgatggaatagga tcaggtacaacatcctgctcagctgatatggctttattagctcgtgaaaaatgcctgaca ttcttatgtgagaaaatgagtcaattccttgagctgactgattatcagaagaatgaacta aagatttatgacagaacaaaggagaaagagtttgtgtggatggacaactttatgggaatc caccccttttttattccaagaggccctgttctccagaggaacagcattacagattatgct ctaaatgccgggactacagcagtgaatgcacaaagactattaagagccctacagcttaac aaacctattttgttggaggggtcaccaggagtgggcaagaccagtctagttgctgccctg gcaaaagcctcgggaaactgtcttgttcgaatcaacctgtctgagcaaacggatgtgaca gacttgtttgggacagacttgcctgttgaaggtgggaagggaggagaatttgcctggcgt gatggaccactactagcagcattaaaggctggacactggattgtattagatgagttgaat ctggcttctcagtctgtattagaggggctaaacgcatgctttgaccacagagcagagatt tatgttccagaattgggaatgaattttcatgtacagcacaagatgactaagatttttgga tgccagaatccgtacagacaaggaggtggaagaaagggtctgcccaagtcctttcttaat agatttacacaggtgtatgttgatccactgtcagcagaagatatggagtttattgggaat acgctgtttcctgctattgataaaagtattattgctaaaatggttgctttcaataacaag attgacaaagaaataatggctgaaaaaaagtggggacagaaaggaggaccctgggagttc aacttacgtgatcttttccgctggtgccagcttatgcttgttgaccagtcaccaggatgt tatgatccaggccagcatgtatttttggtatacggagaaagaatgagaaccagggaagac aaagaaaaggttatatctatatttagagacatttttggccaggaggctgatgtgtataca ggaaccagagagtttcacatcactccatataatgttcagattggttattcagttctttct cgtggcaactatattcctcgtcctggcagaaatctctcacttctgcatcactcactgcag tctcttgagtccataatgaaatgcgtgcacatgagctggatggtcatcctggtgggccca gcagctgttggcaaaaccagtcttgttgagctgctggcccatctgactggccatcgactg aaaatcatggcaatgaacagtgcgatggatacaactgaactcctgggtggatttgaacag gttgatatcaataggccatggcaatgcctgttggaaaaagtggagaatgctgtgagcaca ctagtgagggacagtcttcttctgacagaaatttgtgcagatgatgctgaactcgtgctg cgtgcttggagcagtttcatcctgaactacaaacccaaatctctgggtgaaggaagtaga agtgttacagctgaattagtgagcaaactggagggaatacttgtacttacccagcgacta aacaacaaaataaattcttattcaaaggcagagtttgctcacttggtagaagagttccgg cgtttcaagctgcagcaggcccagacagctgaccgtaacagccatggcacttttgagtgg gtggatgggatgttggttcaggccctgcaatctggagactggctgttgatggacaatgtt aacttctgcaacccttctgtgctggaccgcttgaatgctttacttgaaccaggaggtgtt cttaccatgagtgagagaggtgtgatagatggcacaattcctacaatagctcctcatcca aacttcaggcttttcctttccatggatcctgttcatggggaaatatccagagccatgcgg aatcgtgggattgaaatttacattcctggggagaatgatggaaatgtattggacgatctg gatttgaagttactcctgcatggtttgggtttagtgggagatagcatctgtgatgcactt atggctgtgcattcagaaatcacgacagcaatagcaggttctgtgtcatctttgtcacct ttgcttcaggctgctgtgttaattgtgcagcagatacaaagaggccttggattagcaaag tctttttacagagcctgttgggaagtttatggccgctcacaacaactgcaaataaaccag aagcttgtgttagaactggttacgaagcatgcttcatctctggcttcccatgaaacctgg ggtgactccttgctagccatcggattgtggccggactccctacctacaggtctgtttgca gctgaagactcacttctttcgacagtccagagtgatgcacaggtcctaacgtattgtctg aatagactaaaccttaaaaactgcaggacactaccactgactctgcaagatcttcaaaaa attatgcagtccactaattctgaaagtcttaaattcagtgctgttgagatagatgcagac tggatggataaaatggaagttctccaggcttcagtgaaattgttcatagaaaaggcaacc aatcaagattggacattgagagttaaatggcttaactcctttgccaaaaatctgccacag gtgcttgatccagtgtggattcagctggaagcaggtgctgtagcccttggtagtttctat gccagtcccctctcatctggagtcagtaacatgatcaagttgctacagccaactatgaca gatgaacatgtgatgcctttggacccaagatggaatatgcagtttttggatatcattaga aattccatgaactttgatacagaaatggaacacacagatcagcttctaatccttttgaag tctgtagcgaatcgggcagtattatttcttgaccgagaaaaaagaagctacactgagaag aatttgattaccagcaagaagccaagaaatagtgtcttaagaatgtctctagatttccgc aaagatccaggaagttacaactgtcttcctcatgcaatcgtggtcaaccttgctgctttc tttgaactttgggatgcgtttgcatttcactgggtgaagtctactcaggtggccttaagt gatgatgacatgcatgatattttatactgcttgctgtggcgtgaccggttctgggcagtc tctgacactctgacagtggattcgccagggttgtcgcttctgtctctgcactggcactgg gttatgaagcatctaattgacagaattcctcagatgcttattggatcagaccagcacaag gtttccaaggaaattcaatctgtttcacagcagattcagaactgcttggccaatcctgct gttttttctgccagtatgaagatattacagaagtctctaggaagacctcttccttttaag gataaactgggcatggaatgtttctctcagttaaaagttctcagcaagccacttaacatc ttggagctaagattggcctttggagaaagtagatggcaggaaaaaatgtgctgtctgaaa attgctgccactggatggaagatgaagaaagccttgctgcaagctgatggcctgataatt agagccaatcatttagaagatgttagtctaggtcagctaaagatttttttgaaagctgtc cattcacaactgagagcagaaggagttacatatagttattcagaagaaaggtttactgaa gataccatctccaaccagttagaccctgccttgttaaaccagctctgcagtcgggttcag ctgtggcctgcaatggaatacataagcatgctctggcagtacaaactgacagcagattat gtggccaaggcttgtccaagaagggagaactgcagtcaagaactaagtgtatgttcagat ctagttcagcttatagctttttccctgaagttgacaccagctgcttctcaccagctatct ggattgtggcacttgttacaccttaatgaaatatcccctgaagaaatgtctattctgtcc tctcaactcattaatgctgcattagcatccttttggagcagtactttcaccacagatcca gactattggttgacttggaggccgctacctgcaacagaggaaaagaacttttctaaatcc catatgaactgttctgtgaagggcccaggtattttgacccgagccgttttctcaaagtgc ttctttgaaattctaactagcagcagcaagacaagccagtgggatgtgagtgggcttcct gttctgtcatcatcccatgtgacactgggagaatggatggagagggcacagcagcttcat gaagtcagcacagcactatggaccaacctggctgtctcttcaatagcagattttagatac acagatgctagactacaaggaataatgctaggcagacaactctctgccctggtagatctg gttccaatggattttcaagaaaaatttttggcgtgctgtgagaagctctaccttaaggat cctgttgcatatgagtaccttttcaagatacttagaagcatcactgatcaagagttactt cctaaagaattcctgtttctcctgctcacttgcttgcagcagttctttggggaagggctt aaggagttaccagagacagcttggcgaggaagcctctgggtgaatattggtttggtgcag atccaggtgtggcttccgcagaccaggtttgatccagctgttaaaagagaatacaagctc aagtatgcagaagaagagttacaccagctggagtgtgaatggaaaacaaatgatttttca tcccagctgcatacaggaaaaagcattgaagatgaagcaatcagcaactatattcatccc catctcagactgttgcgtgaaagaatgcaaaggttgaaggagcaaattagcagtctttcc agaaaaaaggccttcaggcctccagctccaccctatgattgcttatatcaggaggctcac cagtacatcaacagcatagcacaggtctcttcagtccaagatcttttagcccgccttctg cagttcctccgtggggaaaggcctaaatcactccaggcaatacaaaacctgttaaatgaa gaagcatcttggcaacaatcacaccatcagtttagaagacacctggcagaggagtatgct gtattccctgatgccatcattccactgcaagctgccatcttacagttgcaacatggcatg cgattagtggcctctgaagtttatacagtgctcaaaagttttgtgcgtccagctgatctg accaacctcctcacttctttgttgacatttccttctgttggccatgcctttcccacttac ttggctcgtgcagaaattttatgctcagtgaattcagttgaggtccttcatggacttaaa aagttttctctgaagcactctgaagtagaatctgagggagtagagcagccttgcccaact ctggaacagctcttagtgaatgctttgttacatcttcgatgccatgtactatccagagga gagatggacaagaaatctctgcagctttttagacatctgtgtcaggcaattataaatgaa tgggatgaacaggagcgccgtgcccaagagcgggaggcaatggaacgcagtctgtacaga tacagaagtaaaagtcatgggaaaggaaggagtgaggaagaggaagaagaagaatttagg aggagatttccccttcatgaagaggactttgaagatatcacagctcagccaagcctagaa gaaaaaatggaaactaaagatctattggaagaccagctggaagttgatagagcccttttg tccaagagctctatgcaaacagtaatgatggttcatcaagagttgtgcttaaactttgct cgatccctgtggtatcaacagagtcagccttctcatcaagccaaacattatttcagtaca tttatttcctgttaccagactggtgcatgtctggtgtcacaattctatcctttaattggt gctgaaatgaatgatagtcttttgggaagccaacttctagttagcactcttcttcacaat accttttttgaggaattaacttcagatcttgtgctgcagcaggatggcccatatgacttc taccagcatcctaatgttcagcaagtgcgacaatgccaacctgtacttgataattttgct aaagaagtaaatgggctactgcaggaatggccggagcatccagtacttgtgcagctgtta gttgtgatggacagaatccggagttttcccctgtctagtcctctctcaaagttcctgaat ggcttggaaattcttcttgcaaaggcacaggattgggaggaaaatgctagtcgagctttg tccttgcgaaaacatcttgatttggtcacacagctgattattcagtggcgtagattggag ttgaattgctggtcagtaagtttggacaatattatgaagcagcatgtagagaaatccaca aaacactggttctcaatctatcagatgattgagacatatgttcaagaacagacagaggca aacacagaagaaactgagcaaatggatctgaaaacgctggtcagcatgctacaagctttc attgaaggatccacgctgggagagtttcatgcacgacttcaagcactactggttttccac tgccatgtcttgctgatgcctcaagtggcagaaaaggacgttctgtgtagcatcttgtgg aatctatacaattattataagcagttttcagagtgtgttgaggccagaatcactgaactt cgtcaacctatagaaaaggaacttaaggaatttgtgaaaatttcaaagtggaatgatgtc agcttctgggctataaaacaatcagttgaaaaaatacgcaggaccctctttaaattcatg aagaagtttgaagctgttctggatgagccatgtcagcctgccttggtggaaattggtaag gaagagcagctggactgcttgcaaaagcaggaagaatctgagaacaaagagaccaaagtt cagaggctaaacaacacattaagaaaaattctgtctgctagaacagatgttgccaagagg ttgctcccagaagaatgtcaggatggcattacatttcatacagaatctcttcagtatcgt ctgcctaagcttactaaaaaaatgaagaaaatgtgtaccacagttacagaaaacagttca ttcttaagtctggtggaagatcttgaccagttcacaggtggtatcattgtttctgtagct gaactgcaaaatctaacatttgatcagacagcagataaggagaagcagaaatcagaggca aagcatattcagatgcagaagcaacgggctttgtcagatctctttaaaagccttgctaaa acaggtttgtcataccggaaaggtcttgcttggtcccgttcaaaagactatcatgaaata ctctacctacgtccactggacttgcgtagtgcattaggtgtaagaaattgtacacatgaa ccggatgccacgttgctgacagagatttcttctgcctgggatggatgccagaagtacttc tataggtcacttgcacgccactctagacttcagacagcattattagcacctgccaaggat attggactaggtagcattgaacgatgcaaaggattcactgcacacctcatgcagatgctt gtcagacagagacgatgtcttactgcattgacagaacagtggatcttactaaggaaccta ctgagttgtatacaagagatagattctaggttgactgctgacagagaatataatgtagca tttcctcctcaagacagtcttcaatgctggactgacaaactgcagcaactttccatgcag tgtgtgatggttctcgaggagctgtcttggtttatacaatgctgcccaaaagaagagtta acaaagtgcagtgacaatgaaaggacagatgtcaaaacaaacatttttcagagttcagga cctgaaatgggaaatgtttttacgggaatacctgacctaattccctcagagctaaaatac ctgactccaataacaattgagcaactgcctcctggatgcaggatgcgaaataaggatcag ttatggctgcaggtagctacacaattgaatgcgatgctagcaaatgtgaaggcaatgaaa gcagaagtggacaacataagacagcagtcatgtgagaccttggtttattcctggagagat tttgaagtttgcacgtcagctatgagttgtttgctggaagtctcagctcagttacaagac atagagtccctatttcttccaaatggggaaggcaggcaagctgtaaatcagatggcccta atcaagagcctgaagtatatacaagaagaagttaataatacgtctgcagacttcatagcc tggagaacacagcttcttgattccatgtcaaattgcagtgaaggaaatcaacagtcagat gaagagtttgtggcgcacttctcagcaaaagtggaaactgttatccgtgttgttctgtat gccatccagtgtttggttgagagaaaacaggaagatggaaaagaggaagacaaatctcta gaggaaagtgaggatgcaacctcatttgacctgattaaagcaggacatataactaagctt ttggatgaagatctttctgctgatttggattctttgcatgtgcagaaagcaattttagca gtttcggaactcctggagaacctgaaatcttatggggaagattacacttcaaataaacat aagttcttcaaccagttttgctatttgctggtgcgtctaaagcccatgctctgcaggtat tcagaccttatcctgttctacctcactgtttcactggcatctcacaggagtactggaaaa ttgctttctgttctaacgagcatttttacagagcttgcccaaaaggggttttgtctgcca aaagaattacttgaagatgaagctggagagggagcaacacagtttcatgattatgaggat ggtggtattggagatggggaaggcaagaaggatgtgagcaacaaaatagagagtgaagat caggcaaaagacagttttcaaaagggtgaagagaaggagaaagaggatcaagattctaaa ccagacattgaaggagaagacaatgcaattgaaatgtcagaagactttgaaggaaaaatg catgatggagaacaggagaaaaaagaaaatgatgaaaattcagatgaagaggaggagctg gataagcagatgggaaatcttgataatgctgaagctgatgataaactggatgagaggctc tggggggatgaagatgacgatgatgatgaagatgccagtagtaaaacagaagaaactgga ccaggaatggatgaggaggattcagagctcgttgcaaaagatgacaattcgggcacagga aacaaggataataaaaaacagcctcctaaggatgaggaaaaagaacaacaagaagacgac agtggaaatgaagagaaaatccatgaacaaattgatgagtgtgagtatgatgagaatgaa gtagatccttatcatggccagcaagaaaagcagcccgaagttgaacctttggaccttcct gataatttgaacctggagaatgatgagaagagtgatgaggaggaagaggatgaagaagaa gagaatgcttttgaagtagatgagaaacctgttgatttaagtgaggcagagaagatggaa gaaccgaatgacgagaatactggtgagacagaaagagatgatcaagatgcagaaccagct gaagaaggcatttctgaagataaagaggagaaggaagatgaaggggacaaaaatgctgat gatcaagaagaaaatgcaggggacactgaggatgcagcagcagaagaggaggaagagtca ccaccacctgatgaggaaaaaaatgaatctgctgaagataagggaatccctgctgctgac caaggccttcaacctcaggaagaagagggtaaagataattcagagatggatgaacagctc cctgagcctgaggaaagaatggagcatgaaacacaagggcagactgggcaagaaaacctg cagagtgacagtgctgttgagctggctggagaagcttccgaaagagaccagtctaaagag gaatacggaagtggagcttcaagtgcaaatcaatccgaaggccatgaatccacgcgcatg gcccgtatggcttctcagaagcaaagcagaaaaaatactcagagtttcaagaggaaacct ggtcaggcagacaatgagcgctcaatgggagatcacaatgaacatatccacaagcgactg agaaccatagaatccagcagtgaagcaaagcagaatacaactcagcctaaacaaaatgcg gaagaggctgatgcgtttgaacatattaaacaaggctctgaaagctatgatgcacagaca tatgatgtagctagcaaggagcaagagaaacctattatgcctcttgaagaaaaggaagag ggagattctgaagatgcagctatggaaacagaaatgcagagcaatgaggatctcagagca gtagacacagaggagctgaagccagaaaaaaagaagtctactgccactaaaactcctgga ccaggtgaagtggagccagagatccagacttttgactcagaggatgtcaatgactctaca aaagaaaagctaccaacagtgactgaagagaagccagagagaagcaaagactcgaccata catacagcccatcagttcgtgatggacactccccagcacatcgttagagatcctgaagag ctaagaaaggaacttgaaaggcatttggaagtttggcagacgcagcagtctggaactcca gatgaggagaaggaagcagcacagttgtggcagaggtatttagtactgacagctcctctg tcacagcagctttgtgaacagctacgactcatactggaacccactcaggcagccaaattg aaaggagactacagaacagggaagagactgaacatgcgcaaagtgattccatatattgcc agtcagttccgaaaagataagatctggttgcgaaggaccaagcccagtaaacgacagtac cagatttgcttggctattgatgattcctctagtatgatagacaatcactctaaacagctt gcatatgaatccctggcagttattggaaatgcactgactcttctagaagtgggacaaatt gctgtgtgtagctttggagagactgttcagctgctgcacccattccacgaacagttcagt gaccaatcaggaacacggatattgcgtctttgcaaatttcagcagaagaaaacaaaaata gcccagtttctagaatcatcagcaaatatgtttgctgcagcacaacagttgtctcaaaat attaatccagaaacagcacagctgcttttgattgtatctgatggaagaggccttttcttg gaaggcaaggaacgagtgacagcagcagttcaagcagctcagaatgccaatatctttgtt attttcgtagtgttggacaatcctaattcccgggattccattttggacattaaagtacct atattcaaaggacctggagaattgcctgaaattagatcttacatggaagaattcccattc ccattctacatgatcctcagagatgtgaatgcgcttccagaaactcttagtgatgcactc agacagtggtttgaactggtgaccgcctcagacactttgtag

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