Harpia harpyja (harpy eagle): 128140406
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Entry
128140406 CDS
T10541
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00562
Inositol phosphate metabolism
hhar01100
Metabolic pathways
hhar04020
Calcium signaling pathway
hhar04070
Phosphatidylinositol signaling system
hhar04081
Hormone signaling
hhar04082
Neuroactive ligand signaling
hhar04261
Adrenergic signaling in cardiomyocytes
hhar04270
Vascular smooth muscle contraction
hhar04310
Wnt signaling pathway
hhar04371
Apelin signaling pathway
hhar04540
Gap junction
hhar04621
NOD-like receptor signaling pathway
hhar04912
GnRH signaling pathway
hhar04916
Melanogenesis
Module
hhar_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
128140406 (PLCB1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
128140406 (PLCB1)
04371 Apelin signaling pathway
128140406 (PLCB1)
04020 Calcium signaling pathway
128140406 (PLCB1)
04070 Phosphatidylinositol signaling system
128140406 (PLCB1)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
128140406 (PLCB1)
04081 Hormone signaling
128140406 (PLCB1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
128140406 (PLCB1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
128140406 (PLCB1)
09152 Endocrine system
04912 GnRH signaling pathway
128140406 (PLCB1)
04916 Melanogenesis
128140406 (PLCB1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
128140406 (PLCB1)
04270 Vascular smooth muscle contraction
128140406 (PLCB1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hhar04131
]
128140406 (PLCB1)
Enzymes [BR:
hhar01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
128140406 (PLCB1)
Membrane trafficking [BR:
hhar04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
128140406 (PLCB1)
Endocytosis
Macropinocytosis
Phospholipase C
128140406 (PLCB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PLC-beta_C
PH_14
PI-PLC-Y
PLCB1-4-like_EFh
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
128140406
NCBI-ProteinID:
XP_052640025
LinkDB
All DBs
Position
4:53341355..53762082
Genome browser
AA seq
1219 aa
AA seq
DB search
MAGAQPGVHALQLKPVCVSDTLKKGIKFVKWDDDSTVVTPIILRTDPQGFFFYWTDQNKE
TELLDISLVKDARCGKHARAPKDPKLRELLDTGNLGGRLENRMITVVYGPDLVNISYLNL
VAFQEDIAKEWSDEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFS
ADRKRVETALEACNLPSSRNDSIPQDDFTPDVYRVFLNNLCPRPEIDHIFSEFGAKSKPY
LTVDQMMEFINFKQRDPRLNEILYPPLKQEQVQQLIEKYEPNSNLAKKGQISVDGFMRYL
SGEENGVVPPEKLDLNEDMSHPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRC
VELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPK
QQAKMAEYCRLIFGDALLMDPLEKYPLEPGVPLPSPMDLMYKILVKNKKKSHKCADGSAK
KKLSEQASNTCSDTSSMFEPSSPGAGEAEIESDDDDDYDDDCKKSSMDEGTAGSEAMATE
EMSNLVNYIQPVKFESFEVSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIY
PKGTRVDSSNYMPQVFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKSGYRLKPEFMRRP
DKHFDPFTESIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKALKTKTS
QGNAVNPVWEEETIVFKKVVLPSLACLRLAVYEEGGKFIGHRILPVSAIRPGYHYICLRN
ERNQPLTLPALFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEV
KKEIDHGDAPSEANNEPRPTPAENGVNYTASLTPKPATQVVHSQPAPGSVKAPAKTEDLI
QSVLTEVEAQTVEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTAKYNEIQND
YLRRRAVLEKTAKRDSKKRSETGSPDHSSSTIEQELAALDSEMTQKLVELKEKQQQQLLN
LRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNSQLKKLKETCEKEKKELKKKMDKKRQE
KITEAKSKDKNQMEEEKTEMIRSYIQEVVQYIKRLEDAQSKRQEKLVEKHKEIRQQILDE
KPKLQVELDQEYQDKFKRLPLEILEFVQEAMKGKISEDGDHSSAPCSLASDSGKSNHKPL
QSEEELEEDNPEKVFDTTF
NT seq
3660 nt
NT seq
+upstream
nt +downstream
nt
atggccggggcacagccaggggtgcacgctctccagctcaagcccgtctgcgtctccgac
accctgaagaaaggcatcaaattcgtcaagtgggacgatgactccactgttgtgactcca
attattctcagaacagatccacagggatttttcttttactggacagatcaaaataaggag
actgagctgctagatatcagccttgtcaaagatgccagatgtggaaaacatgccagagct
cccaaggatccaaaactgcgcgaactgttggatactgggaatctaggaggtcgactggaa
aatcgaatgataactgttgtctatggtccagacctggtcaatatatcgtacttgaacttg
gtggcattccaagaggatatagcaaaggaatggtcagatgaagtgttcagtttggcaaca
aatctgttggcacagaacatgtcaagggatgcatttctggaaaaagcttacacaaaactt
aagctgcaggtgactccagaagggcgcattcctctgaagaacatatatcgcttgttttct
gctgacagaaaacgggtagagaccgcattagaagcttgtaatcttccatcttccaggaat
gattcaatccctcaagatgacttcacaccagacgtgtacagggtgttcttaaacaacctc
tgccctcggcctgagatcgaccacatcttttctgagtttggtgccaagagcaaaccatac
cttactgttgatcagatgatggaattcataaattttaagcaacgtgatccacgattaaat
gaaatcctttatccaccgttaaaacaagaacaagttcaacagctgattgagaagtatgaa
cccaacagtaatctagcaaagaaaggacagatatcagtggatggatttatgcggtatctg
agtggagaagaaaacggcgttgttccacctgagaaactggatttaaacgaagatatgtct
cacccactgtcacactatttcatcaattcctcacacaacacctacctcacagctggacag
ctggctggtaactcatcagtggagatgtatcggcaagtgcttttgtcaggctgccgctgt
gtggagctggactgctggaaaggacgaacagctgaagaagagccggtcattacacacgga
ttcactatgacaactgaaatatccttcaaggaagtaatagaagctattgctgaatgtgca
tttaagacatcaccctttccaatcctcctttcctttgaaaatcatgtggattcccctaaa
caacaggcaaaaatggcagagtactgcagattaatatttggagatgcattgcttatggat
ccattggaaaaatacccgcttgaacctggggttcctcttccaagccccatggatttaatg
tacaaaattctggtgaagaataaaaagaagtctcataagtgtgcagatggaagtgcaaaa
aagaagctctcagagcaagcttccaacacgtgcagtgatacgtctagtatgtttgaacct
tcctcccctggagcaggagaagcagagattgagagcgatgatgatgatgactatgatgat
gactgtaaaaagtcgtcgatggatgaaggtactgctggaagtgaggctatggccacagaa
gagatgtctaatctggtgaactacattcagcctgtgaagtttgaatcatttgaagtatca
aaaaaacgcaacaaaagttttgaaatgtcttcctttgtggaaaccaaagggcttgagcaa
cttacgaagtctcctgtggaatttgtggaatacaacaaaatgcagctaagccgaatttac
ccaaagggaacacgtgtagattcttcgaactacatgccacaagtcttttggaacgccggc
tgccaaatggttgctcttaatttccaaactgtagatttgtctatgcaaataaacatggga
atgtacgagtacaatggcaaaagtggatacaggttaaagccagaattcatgagaagacca
gacaaacactttgatccatttactgaaagtatagtggatggaatagtagctaacaccttg
tctgtcaagataatttcgggtcagtttctttctgataaaaaagttggtacctatgtggaa
gtcgacatgtttggcctgcctgtggatacaagaagaaaagctttgaaaaccaagacctct
caaggcaatgcagttaatcctgtctgggaagaggaaaccatagtgtttaagaaggtcgtc
ttaccttccctggcatgtttgaggctagcagtgtatgaagaaggaggcaaatttattggt
catcggatattaccagtctcagcaattcgaccaggctatcactacatttgtctgaggaat
gagaggaaccaacctttgacactgccagctctcttcgtgtacatagaagtcaaagactat
gtacctgatacttatgcagatgtgattgaggccttatccaatccaatcagatatgtaaac
ttgatggagcaaagagctaagcaactggccgcactgaccctggaagatgaagaagaggta
aagaaagagattgaccatggagatgcaccgtccgaagctaacaatgaacctaggccaaca
ccagcagaaaatggagtaaattacactgcctctcttacaccaaaaccagcaactcaggtt
gtccatagccaaccagcaccaggttcggtgaaagcacctgcaaagacagaagatcttatt
cagagtgtcctcacagaagtagaagcacagactgttgaggagctaaagcaacagaagtct
tttgtcaagcttcagaagaagcactacaaggaaatgaaggaccttgtaaagaggcaccac
aagaaaaccaccgaccttatcaaagagcacactgcaaagtataatgaaatccaaaatgac
tacctgcgacgaagagcagttttagaaaaaacagcaaaaagagacagtaagaaaagatct
gaaacgggcagcccagaccacagttcttcaactattgaacaggaattagctgcacttgac
tctgaaatgacccagaagctagtcgagctgaaggagaagcaacaacagcaactgctaaat
ctccgacaggagcagtattacagcgaaaagtaccagaaacgagagcacattaagctgctt
attcagaagttgacagatgtagcagaggagtgtcagaacagccagctaaagaaactgaaa
gaaacatgtgaaaaagaaaagaaagaattgaagaaaaaaatggacaagaagaggcaggag
aagatcacagaagcaaagtccaaggataaaaatcaaatggaagaagagaagacggaaatg
attcgatcatatatccaggaagtggtgcagtacataaaacggctagaagatgctcagagt
aaaagacaggagaaacttgtagaaaaacacaaggagattcgtcagcaaatactggatgaa
aagcctaagttgcaggtggaacttgatcaggaatatcaagacaaattcaaaagactgcct
ttggaaattctggagttcgtacaggaagccatgaaagggaaaatcagcgaagatggagac
cacagttctgccccctgttccctggcatctgatagtggaaaatcaaatcataaacctctg
caaagtgaagaggaattggaagaagataatccagaaaaagtgtttgatactactttttaa
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