Harpia harpyja (harpy eagle): 128140408
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Entry
128140408 CDS
T10541
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00562
Inositol phosphate metabolism
hhar01100
Metabolic pathways
hhar04020
Calcium signaling pathway
hhar04070
Phosphatidylinositol signaling system
hhar04081
Hormone signaling
hhar04082
Neuroactive ligand signaling
hhar04261
Adrenergic signaling in cardiomyocytes
hhar04270
Vascular smooth muscle contraction
hhar04310
Wnt signaling pathway
hhar04371
Apelin signaling pathway
hhar04540
Gap junction
hhar04621
NOD-like receptor signaling pathway
hhar04912
GnRH signaling pathway
hhar04916
Melanogenesis
Module
hhar_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
Enzymes [BR:
hhar01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
128140408 (PLCB4)
Membrane trafficking [BR:
hhar04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
128140408 (PLCB4)
Endocytosis
Macropinocytosis
Phospholipase C
128140408 (PLCB4)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Other DBs
NCBI-GeneID:
128140408
NCBI-ProteinID:
XP_052640028
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Position
4:53803895..54022039
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AA seq
1206 aa
AA seq
DB search
MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESNCLFQVDEFGFFLSWRSEGKEGQVL
ECSLINSVRFGAVPKDPKILSALEAVGKSESELEGRIVCVCSGTDLVNISFTFMVAENTE
IAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGVISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQPLETHPLDPGKALPSPNDLRRKILIKNKRLKPEVEKKQLDALKKM
MEAGETSAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKAVE
DSEQENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNI
HHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS
LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI
SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLA
VLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGF
GDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQ
SSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAK
EHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCLELKKETEIKIQALTSD
HKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFS
HDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQASNSGL
KPQQAN
NT seq
3621 nt
NT seq
+upstream
nt +downstream
nt
atggcaaaaccttacgaatttaactggcagaagccagttccctcttttatgcaagatgga
gctgtgtttgatagatatgaagaggaatcttttgtctttgaaagcaactgtctcttccaa
gtggatgaatttggcttttttctgagctggagaagtgaaggaaaggaaggacaggtatta
gaatgctccctgatcaacagtgttcgttttggagctgtaccaaaggatcccaaaatacta
tctgcacttgaggctgttggaaaatcagaaagtgagttggaaggacggatagtgtgtgtt
tgcagtggcacagatctggtgaacatcagcttcactttcatggtagcggaaaacacagaa
atagccaagcaatgggtagaagggcttgggtccatcatacataactttagagctaacaat
gtcagtccaatgacatgtctcaagaaacactggatgaaactggcctttctaacaaacaca
aatgggaaaattccagttcggagcattaccagaacctttgcatcaggtaaaacagaaaaa
gtgatctttcaggcacttaaggaattaggtcttcccagtggaaagaatgatgaaattgag
cctgcagcatttacttacgagaaattttatgagctcacccaaaagatatgtccccgaacg
gacatagaggacctctttaagaagatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagatcctcggctcaatgaaattttattt
cccttttatgacacaaaaagagcaatgcagataattgagacatatgagccagatgaagac
ttgaagagtaaaggtgtcatatcaagtgatgggttttgcagatacttgatgtcagatgaa
aatgccccagttttcctagaccgtctggaattatatcaagaaatggaccatcctttggct
cattatttcatcagctcctctcacaatacatatttaacaggcaggcagtttggtggcaag
tcttcggtggagatgtacagacaagtgcttttggctggatgcaggtgtgttgagctggac
tgttgggatggcaaaggtgaagaccaagaaccaataataacgcatggaaaagcaatgtgt
acagacattcttttcaaggatgtaattcaagccattaaggaaacagcatttgttacatca
gagtatcctgtcattctttcatttgaaaatcactgcagcaaatatcaacagtataagatg
tcaaaatactgtgaagatctttttggcgatctcctgttgaagcagcctctagaaacacat
ccacttgatccaggtaaagccttaccttcacctaatgacctcagaagaaagattctcata
aagaataaaaggttgaaacctgaggtagaaaaaaaacagcttgatgctctgaaaaagatg
atggaggctggggaaacttctgctcctgtaaatatcctagaggatgataatgaagaagaa
atagaaagtgctgaccaggaagaagaagctcatccagagtacaaatttggaagtgacctt
actgtagatgattacagtcaaaaagaagctgttgccatcagcgtcaaaaaggctgttgaa
gattctgagcaagaaaacaataaaaagggtttagtaactgttgaagatgaacaagcgtgg
atggcatcttacaaatatgtaggtgccacaaccaatatacatccatatttatcaacaatg
gtcaactatgctcaacctgtaaaatttcaaggtttcgatgtagcagaagaacgtaatatt
catcataatatgtcctctttcaatgaatcagttggactaggatatttgaagacccatgcc
attgagtttgtgaattacaataaacgacaaatgagtcggatatacccaaagggaggccga
gtggattccagtaattacatgcctcaaattttctggaacgctggctgccagatggtctca
ctgaactatcagaccccagatttagcaatgcagttgaatcaaggaaaatttgaatataat
ggatcatgcggctatctacttaaaccagatttcatgcgacgaccagatcgaacatttgac
cctttctctgaaactcctgtagatggtgtaattgctgcaacgtgttctgtgcaggtaata
tctggtcagttcttatcagacaaaaaaattggtacgtatgtagaagtggatatgtatggt
ttacccacggatacgatacgtaaagaatttcgaacacgcatggtgatgaacaatggtctg
aaccctgtttacaatgaagaatcatttgtatttcgaaaggttattctccctgatcttgct
gtcctgagaatagcagtgtatgatgacaataataagttgattggtcagaggatcctgcct
ctggatggtctgcaagcaggttacagacacatttcccttcggaatgagggcaacaaacca
ctctctcttccaacggttttctgcaacattgtgcttaaaacatatgtgcctgatggtttt
ggagatattgtggatgctttatcagatccaaagaaatttttgtctatcacagaaaaaaga
gcagaccaaatgagggctatgggtatcgaaactagtgatatagccgatgtaccaaatgac
acttcaaagaatgatagaaaaggaaaagccaataatgcgaaagccaatgtaacgcctcag
agtagctctgaacttcgaccaagtaccaccgcaggctttggatctgggaccgatgctaag
aaaggtatagaccttattcctcaagtgaagatagaagatttaaagcaaatgaaggcttat
ataaagcatttaaagaagcagcagaaagagctgaatgccttaaagaagaaacatgcaaag
gagcacagcgctatgcagaagttgcactgcacacaaattgacaaaatagtggcacaatat
gataaagaaaaggtatcatacgagaaaatgttagagaaggcaatcaagaagaagggagga
agtaattgtcttgaattgaagaaagaaacggaaattaaaattcaggcactaacatcagat
cacaaatctaaggtcaaagagattgtggcacagcacactaaagagtggtctgagatgatc
aatacgcacagtgccgaagagcaagaaatccgcgatttacacttgaaccaacagtgtgaa
ctactgaagaaactgctgattaatgctcatgaacaacaaacccagcagctaaaattttca
catgacagggaaagcaaggaaatgcgtgccaaccaggctaaaatatctatggaaaacagc
aaagccataagccaagacaaatctatcaaaaataaagctgaaagagaaaggcgagtcaga
gaactgaacagcagcaacacaaaaaagttcctggaagaaagaaaaaggctggcaatgaag
cagtcaaaagaaatggatcagttgaaaaaagttcaacttgagcatttagaagtcttggag
aagcagaatgagcagcttttgaaatcctgtcatgcagtgtctcaaacacaaggcaaagga
gatgcagcagatggtgaagctggaagcagagatggatcgcaggccagcaacagtggtcta
aagcctcagcaagcaaattga
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