Harpia harpyja (harpy eagle): 128142785
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Entry
128142785 CDS
T10541
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
hhar Harpia harpyja (harpy eagle)
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhar01001
]
128142785 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hhar04131
]
128142785 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hhar04147
]
128142785 (LRRK2)
Enzymes [BR:
hhar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
128142785 (LRRK2)
Protein kinases [BR:
hhar01001
]
Serine/threonine kinases: TKL group
LRRK family
128142785 (LRRK2)
Membrane trafficking [BR:
hhar04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
128142785 (LRRK2)
Exosome [BR:
hhar04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
128142785 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
Arf
LRR_9
Ank_2
Beta-prop_RSE1_2nd
Gtr1_RagA
T2SSE
AAA_16
LRR_NXF1-5
AAA_22
PduV-EutP
Arm
ABC_tran
Beta-prop_HPS5
TrwB_AAD_bind
MMR_HSR1
nSTAND3
AAA_7
Beta-prop_EML_2
AAA_29
Septin
G-alpha
FtsK_SpoIIIE
Kdo
cobW
NB-ARC
MobB
NACHT
Motif
Other DBs
NCBI-GeneID:
128142785
NCBI-ProteinID:
XP_052645177
LinkDB
All DBs
Position
6:54509738..54580316
Genome browser
AA seq
2533 aa
AA seq
DB search
MASAGPEEGEAAAAREEQALSKLVVRLQNVQERKRQETLVQTLSDLLELAARQSAPRLFS
GKNVHVPLLLVVDLYPGAAGVQQMGWSLLCKLIEICPSTLQNIAPKDVGKDWEVLGVHQQ
ILKMLTVHKGNINLSVIGLKALNLLLMSDVIAFLLLEEEVDVFSLVFNAMHTFPKNEEIQ
QHGCKALHKLFEKVPEEQLTEFVESKDHMIILKVFKEFPEKEEVILPALYSLHSLASPSS
NVEVLMSGNVRCYNVIVEMMKSFPNSETVQEVSCCLLHKLTLGNFFNILVLHKVPEVIVK
AAKTYPENAKLQAAALSCLALLTETIFLNQDLEERKEEEEEEKLCWLEACYRALELHRRN
TDVLEAACWALKNLFLYQRNLHEKIGDGDNQFPIDRAVMLSMLMHSSSKEVFQAAASTLA
ILSQQNVNIRKTLLAKGIHMNVLDIMRKHPHSPEVAESACRILNHVFKGSFPHLDIMTVA
VSEVVKAMRKHEKSLSLQLEALRVLLHFMMPDMKNEHQNGSSRDVGDAAFVLTVKVIKSQ
CLLEGTHSLVLNALNRFIGNPSIQKCGLKLLASVAECTGALEILTQQGATDTVLHTLQMY
PDEQDIQCLGLSLLHSLITRKSLCIATMHVLSTVLVSALRRFKEVTEIQMHGFHTILSIL
GLSPCFAKLLVHESFDTVIFHQMSMCFTDQRDRQFQSLCCKCFAKIAENDDIKNMMLEKA
CVEYNSIMAECLLLLGADINKKTKTNSLIYQVCEKGNNPKLVELLLANGAREQDVRSALA
ISIKRGDSQIISLLLKRLSLDVANSSICLGGFGIGRLEPSWLIPLFPDKLTPLRKQNAGS
ALARMVLKFQMKNISEDRSRASSDLNFSEDGVDKNYDWNLISDPLVDSVFPFSDDIDSEG
SEGSLFTKKKSNSIAVADLYCREMAFQRGSPTLPRHSYSVGPGSDYEPLMKQRRKFLPSD
ESPKGISKFSPHIRPSDSLSSLISEKEYIKSLDLSSNELENIDAISQNSCLTSHLEHLEK
LELHQNALTNIPEQLCENLKCLTYLDLHSNRFTSFPTYLLKMNCIANLDISRNDIGPSFA
LDPYLRCPTLKQLNLSYNQLVCTPEFLTNVAENLEQLLLEGNKISCLCSPICLKELKILN
ISKNNISSLAENVFMGCTKLEQFNARMNALEIIPDLSSSITSLKLSQNHFINVPEAILLL
PHLRSVDLSQNKIISLPGPMHWKSLNLRELLFNYNQIDVLDLSEKACAWSRLEKLHLSHN
KLKEIPPQIGFLENLTSLDVSHNPDLRFFPDEMGRLSKIWDLPLEGLHLNLDFKHVGFKA
RDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKCKRTELGSPKATVGIDVKD
WIIQGKGKMKKELILNVWDFGGQEEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWL
FNIKARASTSPVILVGTHLDVSDEMQRKACMSKITRELLNKRGFPAIQDYHFVNATEESD
SIIRLRKIIIKESLHFKIRDQPVVGQLIPDSYLELEKRILLERKNVPVEFPVIDQKRLLE
LVQESQLQLDENELPHSIHFLNESGVLLHFQDPALQLRDLYFVDPKWLCKIMAQILMVKV
EGFSKYPKGIVKRSDVEKFLLKKSKFPKIYMSQYFKLLEKFQIALPLGEDQLLIPSSLSD
HRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWR
QGIYLNWSPEAYCLVESAVFDNNPDSFLKITAPSCRKGCILLGQVVDHIDSLMEEWFPGL
LDIDVCGEGETLLKKWALYSFQDGEEHQKILLDDLLKKAEEGDLLVNPDQPRHTIPIAQI
APDLILADLPRNIMLNNDDLEFDEAPEFLLGDGGFGSVYRASYGGEEVAVKIFNKHTSLR
LLRQELAVLCHLHHPSLVSLLAAAIRPRMLVMELALKGSLDRLLQQDNASLTRTLQHRIA
LHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNSAVIAKIADYGIAQYCCRMGIKTSEGT
PGFRAPEVARGNVIYNQQADVYSFGLLLYDILTGGGRIMEGLKFPNEFDELAIQGKLPDP
VKEYGCAPWPKVENLIRKCLKENPQERPTSSQVYEILNSAELICLMRYVSIPSTSTAECM
VAANQSCKKAGVWIGNGNTEKAQLSFVNLNTDGHTCEDIADSKILSLALVTLPTEKENWI
VAGTQSGSLWAVNTEDETRRHRLQKMSDSITCLYCNSLSKQSKQKNFFLVGTADGRLAVF
EDKAVKCKGATPLKILTVGNVSTPLMCLNESSYLSEKNIIWGGCGTKIIALTSDFSVQKL
IETKTSQLFCHNAYSDANIISIAIDKSIYLAKKNSHFVEIWDKKTEKLSELIDCAHFLKD
KVEKLNKESKHKLAYSGRVKTICLQKNTALWIGTGGGHILLLDLSTRRPVRVIDNFCDSV
RVMITAQLGSLKNVVLVLGYCYKSDTEDNKYHKELQSCVSVWDINLPHEVQNLKKHIEMR
QELAEKMKSFSLD
NT seq
7602 nt
NT seq
+upstream
nt +downstream
nt
atggccagcgccggccctgaggagggggaggcggcggcggcgagggaggaacaagccctg
agcaagctggtcgtccggctccagaacgtccaggagaggaagcggcaggagacgctggtg
cagaccctgagcgacctgctggagctggcggcccggcagagcgctccccggctcttcagc
ggcaaaaacgtccatgtgcccttgctgctggtggtggacctgtacccgggagcggcgggc
gtgcagcagatgggttggtcacttctttgtaaattaatagaaatttgtccaagtactcta
cagaacatagctcctaaggatgttgggaaggactgggaagtactgggtgttcaccagcag
attcttaaaatgctcacagttcacaaaggaaatataaatctctcagtaataggactgaaa
gcattaaatctactcctcatgtcagatgtaattgctttcctgctcttggaggaagaggtg
gatgtgttttccttggtatttaatgccatgcacaccttccctaaaaatgaagagatccag
caacatggatgtaaagcattacacaaactttttgagaaagttccagaagagcagctgact
gaatttgttgaaagcaaagatcatatgatcatactgaaagtatttaaagagtttcccgag
aaagaagaggtgattcttcctgcactttattcattacattccttagctagtccatccagc
aatgttgaagtgctcatgtctggaaatgttcgctgctacaacgttatagtggaaatgatg
aaaagtttccccaatagtgaaacagttcaggaagtgagttgctgtttgttgcataagctt
acattgggaaattttttcaatatccttgtattacataaagttccagaagtcattgtgaag
gctgctaaaacatatcctgaaaatgcaaagttacaagctgcagctctcagttgtttagct
cttctaactgaaacaatattcttaaaccaagacttagaagaaagaaaagaagaggaggag
gaagaaaaattatgctggttggaagcatgttacagagcattagaactgcaccgaagaaac
acagatgtgctggaggctgcatgctgggctttgaaaaatctgtttctgtatcaacgcaac
cttcatgagaagattggagatggagataatcagttcccaatagacagagcagtgatgctg
tccatgctgatgcactcatcttcaaaagaagtgtttcaggcagctgctagtaccttggca
attttgtcacaacaaaatgtaaatattaggaagacacttttggctaaaggaatacatatg
aatgttttggatataatgaggaaacatccacattctcctgaagttgctgaaagtgcctgc
agaattctgaatcatgttttcaaaggaagtttccctcatctggatataatgacagtagct
gtatcagaagttgtaaaagccatgaggaaacatgaaaaatcactctctctacaactggaa
gcacttcgagtccttttacactttatgatgcccgatatgaagaatgaacaccagaatggt
tcttccagagatgtgggagatgctgcctttgtacttacagtaaaagtcattaaaagccag
tgtctgttggagggaactcattcgttggtgcttaatgctttgaaccggtttattggaaat
cctagcattcagaagtgtggattaaaactacttgcttctgtagctgagtgcactggtgca
ctagaaattttaacccagcaaggagctactgacactgtgcttcacaccctacagatgtat
ccagacgaacaagacatacagtgtttgggtttgagtcttctacactctttgattacaaga
aaaagtttgtgtattgcaactatgcatgtcctatcaacagttctggtttctgctctgcga
cgatttaaagaggtcactgaaatccagatgcatggatttcatacaatcttgtcaattctt
ggtttatcgccttgttttgcaaagctgctggtacatgaatcatttgacacagtcattttc
caccagatgtctatgtgtttcactgaccagcgagatcgacagtttcaaagcctgtgttgt
aaatgttttgctaaaatagctgaaaatgatgatataaaaaatatgatgctggaaaaagca
tgtgttgagtacaatagtattatggctgaatgtttacttctactgggagctgatattaat
aagaagacaaagacaaactctttgatctatcaggtttgtgagaaaggaaataatcctaaa
ttggtggaattgctattagccaacggtgctagagagcaggatgttcgaagtgctttagcc
atcagtataaagagaggagatagccaaatcatcagcttgctcttaaagaggcttagcctt
gatgtcgccaacagcagtatatgtcttggaggatttggtattgggagactagaaccttcc
tggctcattcctttgttcccagataaacttactccattaagaaaacaaaatgcaggttct
gcactggcaagaatggtgcttaaattccagatgaagaatatttcagaggatagatcaaga
gcctcctctgatctaaacttctctgaagacggagtggataaaaactatgattggaattta
atttctgacccattagtggacagtgtttttcctttcagtgatgatattgatagtgaagga
agtgaaggttcactttttacaaaaaagaagtccaattccattgcagttgctgacttatat
tgtagggaaatggcatttcaaagaggttctcctactttgccgcgacattcctactctgtg
ggacctggctcagattatgaaccattaatgaaacaaagaagaaaattcttgccttcagat
gaatcccccaaaggcatctcaaaattttcaccacatataagaccatcagacagtctttct
tcattgatctcagagaaagaatatattaaatcactagatctttcatcaaatgagctggag
aacattgatgccatcagccagaatagctgcttaactagtcatctggaacatcttgagaaa
ctggagctccaccaaaatgctcttacaaacattccagaacaactgtgtgaaaacttgaaa
tgcttgacttacttggatttgcacagtaaccgattcacttcttttccaacttacttactg
aaaatgaattgtattgcaaatcttgatatctctcgaaatgacattggaccttcctttgct
ttggatccatacctcagatgtccaactctaaagcaacttaatctttcatacaatcagttg
gtgtgcactcctgaatttcttacaaatgttgctgaaaatctggaacagctattgctagaa
ggaaacaaaatttcatgcttatgttcacctatatgcttgaaagaactgaaaattttaaac
attagtaagaacaatatttcatcccttgctgagaatgtcttcatgggctgtacaaagctg
gagcagttcaatgccaggatgaatgctcttgaaataatacctgacttgtcatccagcata
acaagcttaaaattatcccaaaatcattttattaatgttccagaagcaattcttcttcta
ccacatttgcgatcagtagatttaagccaaaacaagatcataagcctgcctggaccaatg
cactggaaatcattaaacttaagggagctgttatttaattataatcaaatagacgtcttg
gacttaagtgaaaaggcatgtgcatggtctaggctagaaaagctacacctgtcccacaac
aagttaaaggagattcctcctcagattggcttcctagagaatttgacttctctggatgta
agtcataatcccgatttgagattctttccagatgaaatgggaagactgtccaaaatctgg
gatcttcctttggaaggtctccatcttaatttagacttcaaacatgtgggattcaaagcc
agagacattatcagatttcttcaacaacgactgaagaaggctgtaccttataacagaatg
aagctcatgattgttggaaacactggcagtgggaaaaccaccctgctacaacaactaatg
aagtgcaaacgaacagaattgggctctccaaaagctacagtaggcattgatgtaaaagac
tggatcattcaagggaaaggcaaaatgaagaaagagcttatattaaatgtgtgggatttt
ggaggacaagaggaattctacagtacccatcctcattttatgacccaaagagctttatat
ctcgctgtttatgatctcagcaaaggacaagcagaggtggatgctatgaagccatggctt
tttaacatcaaggctcgagcttcaacatcacccgtcattcttgttggcactcatttagat
gtttctgatgaaatgcaacgtaaggcctgcatgagtaaaattactagagagctgttgaat
aagcgaggcttcccagcaatccaagattatcactttgtgaatgctacggaagaatccgat
tccattatcagacttcggaaaatcataataaaggaaagtcttcacttcaagatcagagat
caaccagtggtcggtcagctaattcctgacagctacttggagctggagaagagaattttg
ctggaacgtaaaaatgtcccagttgaatttcctgtgattgatcagaaacgtttactggaa
ctggtacaagaaagccagttacaattggatgaaaatgaactccctcactcaattcacttt
cttaatgaatcaggtgtactccttcattttcaagacccagcactacagctaagagatctg
tattttgtagatcctaagtggctatgtaaaatcatggcacagattctgatggtgaaagtg
gaaggcttttctaaatatcctaagggaattgtaaagcgttcagatgtggaaaaattcctt
ttaaagaagagcaagtttcccaagatctacatgtcacaatacttcaagcttctggaaaag
tttcagattgctttgccattaggagaggatcaactactaatcccaagcagtttgtctgat
cacagacctgttatagaacttccccactgtgaaaattcagaaattatcatcaggctttat
gagatgccatactttcctatgggattttggtccaggctgatcaacaggttgcttgaaata
tcaccttacatgctgtcaggaagagagcgagctcttcgtcctaatagaatgtattggaga
caaggcatctacttgaattggtctcctgaagcgtattgtctagtggaatcagcagtattt
gacaacaacccagacagttttttgaaaattacagcaccttcttgcagaaaagggtgcatc
cttttggggcaagttgtggatcacatagattctcttatggaagaatggtttccaggtttg
ctggatatagatgtatgtggtgaaggggaaacactgttgaagaaatgggctctgtacagc
tttcaggatggtgaagaacaccaaaaaatactacttgatgacttacttaaaaaagctgaa
gaaggtgaccttttggtaaatccagatcaaccaaggcataccattccaatagctcaaatt
gctcctgatctgatattggctgacttgcctagaaatattatgttgaacaatgatgacctg
gaatttgatgaagctcctgaatttctcttgggtgatggtgggtttggatctgtgtaccgt
gcatcctatggtggagaagaggttgctgtaaagattttcaataaacatacttccctcagg
ctcctaagacaagagcttgcagtgctttgtcatctccatcaccctagtttagtgtctctg
ctggctgctgcaatccgtccccggatgctggtgatggaattagcccttaaaggatctctt
gatcgtttgcttcaacaagacaatgcaagtttaactagaacacttcagcacaggatagct
ctacatgtagctgatggcttaaggtatctgcattcagcaatgatcatctaccgtgattta
aagcctcacaatgtgttgctctttaccctatatcctaattcagctgttattgctaaaata
gctgactatggcattgcccagtattgttgccgaatgggaataaaaacctccgaaggcaca
ccaggatttcgagcaccggaggtggccagaggaaatgttatttacaatcagcaagctgat
gtttattcatttggcttgctgctctatgacattttaacaggaggaggtagaataatggaa
ggcttgaagtttccaaatgaatttgatgaattagcaatacaaggaaagttaccagatcct
gtcaaagaatatgggtgtgccccctggcctaaagttgaaaatttaattagaaagtgtttg
aaggaaaaccctcaggaacgaccaacatcttcccaggtttatgagatcctgaattctgca
gagcttatctgtttgatgaggtatgtttcaatacccagcacatctacagcagagtgcatg
gtagctgccaatcaaagctgcaagaaggcaggagtctggataggcaatgggaacacagaa
aaagcacaactttcatttgttaacctaaatacagatggacatacttgtgaggatattgca
gatagcaaaattttaagtttggccttagtaacccttcctactgagaaagaaaactggatt
gtagcaggaacccagtctggttctctctgggcagttaacacagaagatgaaacaagaagg
catcgtctgcagaagatgtcagattccatcacttgtttatactgtaattctctttcaaag
caaagcaaacagaagaatttcttcttggtaggcacagctgatggcagactggcagttttt
gaagacaaagcagtaaagtgtaagggtgctacacctttgaagatactaactgtaggaaat
gttagcacaccactgatgtgcttaaacgaatcctcatacttatctgaaaaaaatataatc
tggggaggctgtggaacaaagatcattgccttaactagtgatttctctgttcaaaagctc
attgaaacaaagacaagtcaactgttctgtcataatgcttacagtgatgcaaacattatt
tcaatagcaatagacaaatccatctacttggcaaagaaaaacagccattttgtggaaatc
tgggacaagaagacagaaaaactttctgaactaattgattgtgcacattttcttaaggac
aaagtggaaaaactaaataaggaatcaaaacataaactggcttattctggaagagtgaag
acaatttgcctgcagaaaaatacggcactgtggataggaacaggaggaggacatatcttg
ctgcttgatttatcgacacgtcgtcctgtacgagttatagacaacttttgtgattctgtt
agagtcatgataacagctcagctagggagtctcaagaatgtggtgctggttttgggatat
tgctataaaagtgacaccgaagacaacaaatatcacaaagaattacaatcctgcgtgtca
gtgtgggacattaacctgccccatgaagtgcaaaacctgaaaaaacatatagaaatgaga
caggaattagcagaaaaaatgaagagcttttctttggattga
DBGET
integrated database retrieval system
