Harpia harpyja (harpy eagle): 128146598
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Entry
128146598 CDS
T10541
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00140
Steroid hormone biosynthesis
hhar01100
Metabolic pathways
Module
hhar_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
128146598 (HSD17B2)
Enzymes [BR:
hhar01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
128146598 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
128146598 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Epimerase
Motif
Other DBs
NCBI-GeneID:
128146598
NCBI-ProteinID:
XP_052654079
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Position
9:complement(5428926..5441358)
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AA seq
392 aa
AA seq
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MDALAGSPFGWLCAGVTLLFGVTVLCVAKRSPVEKANVLVWRLLPASLGLLCVAVATLGA
GGGLAVFCGTCLVSSAYLGSRALLPVGDKAVLVTGSDTGIGHALAKYLDNLGFVVFAGVL
NKDGPGAEQLRQTCSRRLSLLQLDITNANQVKEAYLKVSEKVQNTGLWGVVNNAGVLGFP
ADGELLPMSTYRQCMEVNFFGAVEVSKTFLPLLRKSQGRLVNVSSMAGGIPLPRCAAYGA
SKAALSMFSGVMRQELSKWGIKVAAIHPSGFRTGIQGTSDLWDKQEKELMENLPARTRQD
YGEDYLLGLKDYLLRIPAYCDADLSPVLNAILHALLAKRPQGLYTPGKGAYMPLCIFCYF
PLWFYDFFISKMLSTESVPRVLRTSEAESKNL
NT seq
1179 nt
NT seq
+upstream
nt +downstream
nt
atggatgctctcgccggcagccccttcggatggctctgcgcgggcgtcaccctgcttttc
ggggtgaccgtgctctgcgtggccaagaggagcccggtggagaaagcaaacgtgctggtc
tggaggctcctgcccgcctcgctggggctgctgtgcgtggccgtggccacgctgggggcc
ggcggggggctggcggtgttttgcggcacgtgcctcgtctcctccgcgtacctgggcagc
agggcgctgctgcccgtgggcgacaaagccgtgctcgtcacaggaagtgacactgggatt
ggacatgcactggctaaatacctggacaacttaggttttgttgtgtttgctggggttttg
aataaggatggacctggagctgagcaactgagacaaacctgttctcggagactctctctc
ctgcagctggatataaccaatgccaaccaagtcaaggaagcctatctaaaagtctcagag
aaggtgcaaaatacaggactctggggagttgtgaacaacgcaggcgtcctgggcttccct
gccgacggcgagctgctgcccatgagcacgtacaggcagtgcatggaggtgaatttcttt
ggggctgtagaggtgtccaagaccttcttaccgttacttcggaaatcccaggggaggctg
gttaacgtgtccagcatggcaggaggcattccactaccgaggtgtgctgcatacggtgca
tcaaaagcagctctgtccatgttttctggagtaatgaggcaagagctttccaaatgggga
attaaagttgctgcaattcatccgtcaggcttccgaacaggtatacaaggcacatccgac
ctgtgggataagcaagaaaaggagctgatggagaacctcccagcacgcacaaggcaagac
tacggtgaggactacctcctggggctgaaggactacctcctgcgcattcccgcgtactgc
gatgccgacctctcgcccgtgctgaacgctatcctgcacgctttgctggccaagagacca
cagggcttgtacacccctggcaaaggggcttacatgcccctctgcatcttctgctacttt
cctctctggttctatgactttttcattagtaagatgctgagtactgagtctgtcccaagg
gtgctgagaacatcagaagctgaaagcaagaatctctaa
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