Harpia harpyja (harpy eagle): 128147521
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Entry
128147521 CDS
T10541
Symbol
TYK2
Name
(RefSeq) LOW QUALITY PROTEIN: non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar04217
Necroptosis
hhar04620
Toll-like receptor signaling pathway
hhar04621
NOD-like receptor signaling pathway
hhar05164
Influenza A
hhar05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
128147521 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
128147521 (TYK2)
04621 NOD-like receptor signaling pathway
128147521 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05164 Influenza A
128147521 (TYK2)
05168 Herpes simplex virus 1 infection
128147521 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhar01001
]
128147521 (TYK2)
Enzymes [BR:
hhar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
128147521 (TYK2)
Protein kinases [BR:
hhar01001
]
Non-receptor tyrosine kinases
JAK family [OT]
128147521 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
SH2_1
Kinase-like
Kdo
SH2
ABC1
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
128147521
NCBI-ProteinID:
XP_052656111
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All DBs
Position
10:620273..631007
Genome browser
AA seq
1074 aa
AA seq
DB search
MNDKEPAVYRNVPRQSDSPDEKLQGGALLDKSSFEYLFEQGKFEFINDIASLKDLQTEQE
IQRFKNESLGMAVLHLSHIAIKKGISLEEVARKYSFKDCIPRSFYRQIQQNNYLTKFRMK
NVFKKFVQRFQRHTVSTGKLTVQDIMYKYLATLEHLAPRFGSELFPVLSLETSSEGEKVQ
LYVNGGHSQLEHGQALLPKDRPVTHEVLVTGTTGIQWRPMPVESIENFSHRGYFGRKSRN
KELEPKGPTQPAERSEPKWVHFCDFREITHIVVKDCRVSINRQDNKCLEVVLPSPESALS
LVSLVDGYFRLTADSSHYLCHEVAPPRLVMSILNGIHGPMQEEFVFAKLRREEQEEGLYI
IRWSVLDFNRMILSVVKRGHQQAPGVQGALKYRQFRIQKKGNSFVLEGWDREFSTLRELL
DVLKGCTLKSGDESFTVKRCCPPKPGEISDLLITRKVKDSTKQILNLTQLSFHQIRKNEI
TQRAHLGQGTRTNIYDGVLNICGTTGADDEAEYFSTEQNNNSREMHVVLKVLDPSHRDIA
LAFFETASLMSQVSHVHLAFVHGVCVRGSENIMVEEFVEHGPLDVLLRKEKGRVTVGWKI
TVAKQLASALSYLEDKNLVHGNVCAKNILLARKGLEDGSVPFVKLSDPGVSFTVLSREER
VDRIPWIAPECVRDVGNLSTAADKWSFGTTLLEICFDADVPLKERTPSEKERFYEKRHRL
PEPSCKELATLICQCLNYTPVERPSFRTILRDLTQLQPHNLVDVTSVNPDFPVSDPTVFQ
KRYLKKIRELGEGHFGKVSLYCYDPTNDGTGEMVAVKSLKSGCSQQLLTSWKREIEILKT
LYHENIVKYKGCCSEQGEKIVQLIMEYVPLGSLRDYLPKHNVSLAHILLFAQQICEGMAY
LHSLHYIHRDLAARNVLLENENVVKIGDFGLAKAIPEGHEYYRVCEDGDSPVFWYAVECL
KECKFYYASDVWSFGVTLYELLTRCDSSQSPPVKFIEMIGATQGQMTVLRLIELLDRGKR
LPSPKDCPCEIYRLMKNCWEAEASFRPAFHNLVPILKNFHEKYRAQAPSVFSLC
NT seq
3225 nt
NT seq
+upstream
nt +downstream
nt
atgaacgacaaggaaccggcggtttatcgcaatgtgccccgacagagcgattcccccgat
gagaagctgcaaggaggagccttgctcgacaaatcgtccttcgagtatctgtttgagcag
gggaaatttgaattcatcaatgacatcgcgtctttgaaagacctccagactgaacaggag
atccagaggttcaagaacgaaagcttgggcatggccgtgcttcacctctcgcacatcgcc
atcaaaaaaggcatctcccttgaggaagtggccagaaaatacagcttcaaggactgcatc
ccacgttccttctaccgccagatccagcagaacaactacctgaccaaattccgcatgaag
aacgtcttcaagaagtttgtgcagcgtttccagcgacacacggtcagcaccggcaagctg
acagtgcaggacatcatgtacaaatacctggctaccttggagcacctcgcacctcgcttt
gggagcgagctcttccctgtgctctccttggagacctcctccgagggtgaaaaggtgcag
ctgtacgttaacgggggacattcgcagctggagcacgggcaggcgctgctccccaaggac
cgacctgtcacccacgaagtcctcgtcaccggcacaaccgggatccagtggcggcccatg
cctgtagagagcattgagaacttctcccatcgtgggtattttgggaggaagagcagaaac
aaagagctggagcccaaggggccaactcagccagcagagcggagcgagccaaaatgggtc
catttctgtgatttccgggagatcacacacattgtcgtcaaggactgtagggtcagcatc
aaccggcaggacaacaagtgcctggaagtggttctgccatcccctgagagcgcgctttcc
ttggtttcactggtggatggttatttccgactcacggctgactccagccactacctgtgt
cacgaagtggcaccgccgcgactcgtgatgagcatcttgaacggcatccacgggcccatg
caggaggagtttgtttttgccaagctacgacgggaggagcaggaagaagggctctacatc
atccgctggagtgtccttgacttcaacaggatgattctctccgtggtgaaaaggggccac
cagcaggctcctggggtgcagggagccctcaagtacaggcaattccggatccaaaaaaaa
ggaaactcctttgtgctggaagggtgggaccgggagttttccactttgcgggagctcttg
gatgtactcaagggctgcacgctcaaatctggcgatgaaagcttcacggtgaagagatgc
tgtccgcccaaaccaggagagatctcggacctgctgatcacgcggaaggtgaaggatagc
acgaagcagatccttaacctgacccagctcagcttccaccagatccgcaagaacgagatc
actcagcgagcccacctggggcagggcacccgcacaaacatctacgatggggtgctgaac
atctgcgggaccaccggggccgacgacgaagccgagtatttctccaccgagcagaataac
aacagccgggagatgcacgtggtcctcaaagtcctggatcccagccacagagacatcgcc
ctggcgttttttgagacagccagcctgatgagccaagtgtcgcacgtccacttggctttc
gtgcacggagtctgcgtgcgaggttccgagaatatcatggtggaggagtttgtggaacat
ggacctctggatgtgctgctgcggaaagagaaaggccgggtcaccgtgggctggaaaatc
accgtggccaagcagttggccagtgccttgagctacctggaggacaaaaacctggtgcac
ggcaacgtgtgcgcaaaaaacatcctgctggccaggaaggggctggaagatggatccgtg
cctttcgtgaagctcagtgaccccggagtcagctttacggtgctctctcgagaagagcgc
gtggaccggatcccctggatcgccccggaatgtgtccgggatgtgggaaacctcagcact
gcggctgacaaatggagctttggcaccacgttgctggaaatctgctttgacgccgatgtc
ccactcaaggagcgcactccttcggagaaagaacgtttctacgagaagaggcatcgcctg
cctgagccgtcctgcaaggagctggccaccctcatctgtcagtgcctgaactacaccccc
gtcgagcggccgtccttccggaccatcctgcgggatctcacccagctccagccgcacaac
ctcgtagacgtcacctcggtgaaccccgacttcccggtgtcggaccccaccgtctttcag
aagcgttacctgaaaaagattcgggagctgggggagggtcactttggcaaggtgagcctg
tattgctatgaccccacgaacgacgggacgggggaaatggtggccgtcaaatcactcaaa
tccggctgcagccagcagctgctgaccagttggaagagggaaatcgagatcctcaagacg
ctttatcatgaaaacatcgtcaagtacaagggttgctgcagcgagcagggagagaagatc
gtgcagctgatcatggagtatgtgccgctcggcagcctgcgcgactacttgcccaagcac
aacgtcagcctggcccacatcctgctcttcgcccagcagatatgcgagggcatggcctat
ctgcactccctccactacatccacagggacctcgccgctcgcaacgtgctgctggagaat
gaaaacgtggtgaaaatcggggatttcggtttagccaaagccatccccgagggccacgag
tattaccgcgtctgcgaggacggggacagccccgtcttttggtacgccgtggagtgcctc
aaggagtgtaagttttactacgcgtccgacgtctggtccttcggggtgactctctacgag
ctcctgacccgctgcgactccagccagagccctcccgtgaaattcatcgagatgatcggg
gcgacgcaggggcagatgacggtgctgcggctgatcgagctgctggacagggggaagagg
ctgccgagtcccaaggactgtccttgcgagatttaccggctgatgaagaattgctgggaa
gcagaggcttccttccgcccggccttccacaatctcgtccccatcctcaagaacttccac
gagaaataccgggctcaggctccctctgtcttcagcctctgctga
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