Harpia harpyja (harpy eagle): 128147888
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Entry
128147888 CDS
T10541
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00310
Lysine degradation
hhar01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
128147888 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hhar03036
]
128147888 (DOT1L)
Enzymes [BR:
hhar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
128147888 (DOT1L)
Chromosome and associated proteins [BR:
hhar03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
128147888 (DOT1L)
HMT complexes
Dot1-containing complex
128147888 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
128147888
NCBI-ProteinID:
XP_052657048
LinkDB
All DBs
Position
11:complement(4835928..4913538)
Genome browser
AA seq
1740 aa
AA seq
DB search
MGERLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNTTTPTKVQ
ENKDSGAEEEKAAANSVKKPSPSKARKKKLSKKGRKMAGRKRGRPKKMNTANTERKTKKN
QTALELLHAQTVSQTSSSSPQDAYKSPHSPYYQLPPKVQRHSSNQLLVTPTPPALQKLLD
SFKIQYMQFMAYMKTPQYKASLQQLLEQEKEKNAQLLGTAQQLFTHCQAQKEEIKRLFQQ
KLDELGVKALTYNDLIQAQKEISAHNQQLKEQTKQLEKDNSELRNQSLQLLKARCEELKL
DWSTLSLENLLKEKQALKNQISEKQKHCLELQISIVELEKSQRQQELMQLKSYTPSDESL
SVQLRNKNHLSRDPEADHGRFQLELECSKFPMPHINGMSPELSMNGHATPYEIHNTFSRP
SSKQNTPQYTTSHLDQEIVPCTPNHSSRQKADKMTSLSLPDYTRFSPAKIALRRHLNQDH
GVNGKAATNEMQRADHVKENGLTYPSPGISNGIKLSPQETRPSSPVALPVAGEKVLRERT
SVSNGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRVEKVRSTPSPVHQSRDSSTLE
KQIGASSHNGVSNAAGNKPLALATSGFSYSSGSVAVNGNLTNSPAHLNHSVDQAALDDSG
SLFNSVGSRSSTPQHPLLMMQSRNSGQNSPAHQHSTSPRLNGTSQSLVGVLQYADAQKMF
AEGTKGDLQSDAAFSDPENEAKRRIIFTISPNTGHVKQSPSNKHSPLPTSARLDCGQAHA
QDGKKRGRRKRSSTGNLSGNSGVSPKRKSLPTVSGLFTQPSGSPLNINSMVNNINQPLEI
TAISSPENSLKNSPVPYQDNDQPPVLKKEKPLIQTNGVHYSPLTSDEEQGSEDEHNSSRI
ERKIATISLESKSPQKTVENGISLSGRKQAQSNENMNSSKWKSTFSPISDINLTKTTDSP
LQSVSSLSQNSLFAFRPSSEDSLAIDAKITAHTRKSIAMPSSGADGLSPSTNSTNGFTYN
GGLSTDIGLHSFIDGASLPHKASDVTTSNCSLGFQSQRSKDVGVSETNPFLNKRQLEGLS
STKGDDLNRSGVKGKEIGEISIRTGGSSEKNSLQHNGKVGKGRDRDVEFKNGHNLFISAA
VSSGGLLNGKSLSTAVSSAGNPASSVQTHHPFLNTLTTGSQFPLGPMALQANLNSVTNSS
VLQSLFNSMPAAASLVHVSSAATRLTNSHTMGNFSPGVTGGTVGGIFNHAVPSASSPHQF
GASFSSSAVSSSTVLSLNPLQAVASTSSSSFPPPSSNLVTSSETRSAQHLNRAPVQSVFH
SPPPPPNVSLPPPPPLLASNSEPALLQNLPSIPPGEAFLPSSSAASVQSANASLSIKLAS
LQHKTSRPSFTVHHPPLPRLALAQSAPMITQSNAAGTSAMWVTLGMQSPYASHLSGVKPR
NT seq
5223 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaggctggagctccggctgaagtcgcccgtgggagccgagcccgccgtctac
ccctggccgctgcccgtctacgacaaacaccatgatgctgctcacgaaattattgagaca
attcggtgggtctgtgaagaaatcccagatctcaagcttgctatggaaaactatgtttta
attgactatgatacaaaaagctttgaaagcatgcagaggctttgtgacaaatacaaccga
gccattgatagcattcatcagttgtggaagggaaccacccaaccgatgaaattgaacact
cgtccctccaacgggctcctccggcacatcctgcagcaagtgtataaccactcggtgact
gatccagagaaacttaacaactatgagcccttttccccagaggtttatggagaaacttcc
tttgacttagtggcccaaatgatagatgaaattaaaatgacagaggatgatttgtttgtt
gacttgggcagtggtgtgggtcaggtggtgcttcaagtggctgcagccacaaactgcaaa
catcactatggtgtggagaaagctgatattccagccaaatatgctgagacgatggacaga
gagttcagaaagtggatgaaatggtatgggaaaaaacatgcagaatacacactggaaaga
ggtgacttcctctcagaagaatggagagagaggattgcaaacacaagtgttatttttgtg
aataattttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcgaacatg
aaggaaggtgggagaattgtgtcctcaaaaccttttgcacctctaaattttagaattaac
agtcgaaacttgagtgatattggcactataatgagagttgtggaactatcaccactgaaa
ggatctgtgtcatggaccgggaaaccagtttcttactacctgcatactattgaccgaacc
atacttgaaaactatttttctagtctcaaaaatccaaaactcagggaggaacaagaggca
gctagacgtcgtcaacaaagagaaagtaagagcaacacaactactccaacgaaggttcaa
gaaaacaaggattctggtgctgaagaagaaaaggctgcagcaaattctgttaaaaagcca
tctccctccaaagcacggaagaaaaagctaagtaaaaaaggaaggaaaatggcaggcagg
aaacgaggacgtcccaagaaaatgaacactgcaaatacagagcgcaagaccaagaagaac
caaactgcactagaacttctgcatgctcaaactgtttcacagacatcttcatcctctcct
caggatgcatacaagtcacctcatagtccatattaccaactacctcctaaagtgcaacgg
cattcatctaaccagctactggtgacacctaccccacctgcactacagaagctgctagac
tcatttaagatccagtacatgcagttcatggcatacatgaaaactcctcagtataaagca
agtctgcaacagttactggagcaggaaaaggaaaagaatgctcagttactgggaacagca
cagcagttattcacccactgccaggcacagaaagaggaaataaaacgtctttttcagcag
aaacttgatgagttgggagttaaagctctaacatacaatgacctgattcaggctcagaag
gaaatctctgctcacaatcagcaactgaaagaacagacgaaacagctggagaaggataac
agtgaactcaggaaccagagcttacagctgcttaaggcacggtgtgaagaactgaagctg
gattggtcaacattgtcactggagaacttgctgaaagagaagcaggcattgaagaatcag
atttctgagaaacaaaagcactgtttggaattgcagatcagcattgtggaacttgagaaa
agtcaaagacagcaggagctcatgcagctgaaatcgtacacgccgtctgatgagtcactg
tcagtacagctacgcaataaaaaccatttgagccgtgatcctgaggctgatcatggcagg
ttccaactggagcttgaatgctctaagtttcctatgccccacatcaatggcatgagccct
gaactgtccatgaacggccatgctactccctatgaaattcataacacctttagcaggccc
tcttccaagcagaacacccctcagtacacgacctctcacctggaccaagaaatagttccg
tgcaccccaaaccacagcagcagacagaaggcagacaagatgacaagcttgtccttacct
gattataccaggttttccccagctaaaatagcactaaggagacacttgaatcaagaccat
ggagtcaatggaaaagcagcaactaatgagatgcagagagctgaccatgtcaaagagaat
ggccttacatatccaagccctggtatttcaaatggcataaagctgagtcctcaggaaact
cggccctcttccccagtggccttaccagttgcaggcgagaaggttttgagagagagaacc
tctgtgagtaatggagaaactatcaccagcctacctatcagtattcctctcagcacagtg
cagcccaataaactccctgttagtatccctctggccagcgtagtcctacctagccgtgtt
gagaaggtgagaagcacacctagcccagttcatcagagtagagactcatcgacacttgaa
aagcagattggtgctagttctcataatggcgtaagcaatgctgctggaaacaagccactg
gctttggctacctcaggtttttcttactcttctggctccgtggcagtcaatggaaatctt
acaaacagcccagcccatcttaaccatagtgttgatcaggcagctctggacgactctggg
agtctgtttaactcagtagggtctcggagttccactccacaacatcctttgctaatgatg
cagtcaaggaactctgggcaaaactcccctgctcaccagcactcaacaagccccaggtta
aatggcacctcccagagcctggtaggggtattgcaatatgcagatgctcagaagatgttt
gccgaaggaacaaagggggatcttcagtctgatgcagcgttttcagatcctgagaacgag
gccaagagaagaatcatctttacaatctctcctaatacaggacatgtaaaacaatcccct
tccaacaagcacagtcctctgcccacgagcgctcggctggactgtggccaagcacacgcg
caggatgggaagaagcgaggccggcggaagagatcctctactgggaatctcagcgggaac
tccggggtctcccctaaacgcaaatccttacctactgtgtctggactctttacacaacca
tcaggttcaccgctcaatatcaactccatggtcaataacattaaccagcctttagaaata
acagccatttcctctcctgaaaactccctgaagaactctcctgttccttaccaggacaat
gaccagcccccggtactgaaaaaggaaaagcccctcattcagaccaatggcgttcattac
tctcctctaacatcagatgaagagcagggatctgaagatgagcacaatagcagcagaatt
gagaggaaaattgcaacaatatcattggaaagcaaatctccacagaagactgttgaaaat
ggcatcagcttatctgggaggaaacaagcacaaagcaacgaaaacatgaatagcagtaaa
tggaaatctactttttcaccaatatctgacatcaacctgaccaaaactacagacagtccc
ttgcagtcggtttcatctctgagccagaattcgctgtttgccttcaggccgtcctccgag
gatagccttgccatcgacgccaagatcacagcacacacaaggaaaagcattgccatgccc
tcgtctggggcagatgggctcagccctagtacaaattccactaacggattcacgtacaat
ggtggactgtcaactgacattggtttacacagctttatcgatggtgcttctcttccgcat
aaggcttcagatgtgacgacttccaactgctccttgggtttccagtcgcagcgaagcaaa
gatgtgggggtatcggaaacaaatccttttttgaacaagaggcaactcgaaggcctcagc
agcacgaaaggagacgacttaaatcggtcaggggtcaaaggcaaagaaatcggtgaaata
agcattcgtactgggggttcttcagaaaaaaactctttgcagcataacggaaaggttggc
aaaggaagggaccgagatgtggagtttaaaaatggccacaaccttttcatttctgctgct
gtttcatctggtggccttctgaatggtaaaagcctttctactgctgtttcttcagcaggc
aacccagcatcttctgttcagacacaccatcctttcctaaacactttgaccactggatcg
cagttccccctcggccccatggccttgcaagcaaacctcaactcggtgacaaattcctca
gtattgcagtccttatttaattcaatgccagctgctgccagtctggtccacgtgtcatca
gctgcaaccagactgactaattctcacactatggggaacttctctcctggggttacaggt
ggaacagttggaggtatttttaaccatgcggtgccttctgcctcctctcctcatcaattt
ggagccagtttcagcagcagtgctgtctctagcagcacagtgctaagcttaaaccctctg
caggctgttgccagcacctcatcctcatccttcccacccccttcctctaatttagtaaca
tctagtgagactagatctgctcagcacctcaacagagcgccagtgcaatctgtttttcat
tcccctccacctcctcctaacgtgtcattgcccccacctcctccattacttgcttctaac
tccgagcctgcgcttctgcagaacctgccatccatcccacctggcgaagcttttttgcca
tcttcttctgctgcttctgtccaatctgctaatgcttctttgtctattaagctagcttct
ctccagcacaaaacttcccgcccctcctttacagtccatcacccgcctctgccccgtttg
gcgctggcacagtccgcgcccatgatcacgcagtccaacgcagctggcacgtccgctatg
tgggttacacttggcatgcagtctccttatgcttcgcacctttctggggttaagccacga
taa
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integrated database retrieval system
