Harpia harpyja (harpy eagle): 128149015
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Entry
128149015 CDS
T10541
Symbol
MCCC1
Name
(RefSeq) methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial isoform X1
KO
K01968
3-methylcrotonyl-CoA carboxylase alpha subunit [EC:
6.4.1.4
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00280
Valine, leucine and isoleucine degradation
hhar01100
Metabolic pathways
Module
hhar_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
Enzymes [BR:
hhar01000
]
6. Ligases
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.4 methylcrotonoyl-CoA carboxylase
128149015 (MCCC1)
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Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
Dala_Dala_lig_C
ATP-grasp
Biotin_lipoyl_2
RimK
ATP-grasp_3
ATPgrasp_ST
GARS_A
NQRA_N
RnfC_N
ATP-grasp_5
ATP-grasp_4
Motif
Other DBs
NCBI-GeneID:
128149015
NCBI-ProteinID:
XP_052659626
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Position
12:35117881..35142979
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AA seq
735 aa
AA seq
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MALVLAAERGRCCLWALRRQRWNQVQRFVKWASTIGGHNIGKILIANRGEIACRVMRTAK
KMGVKSVAVYSEADRNSMHVAMADEAYCIGPAPSQQSYLAMEKIMQVAKVSAAQAIHPGY
GFLSENTEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKAIMSAAGVPVVEGYHGEDQSDE
CLKEHAKRIGYPVMIKAVRGGGGKGMRIAHSEKEFLDQLESARREAKKSFNDDAMLIEKF
VDNPRHVEVQVFGDQHGNAVYLFERDCSVQRRHQKIIEEAPGPGINPEVRRRLGEAAVKA
AKAVNYVGAGTVEFIMDSKHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVAAGEKIP
LMQEDIVLQGHAFEARIYAEDPNNNFMPGAGPLLHLTTPPPDSFTRIETGVRQGDEVSVH
YDPMIAKLVVWAEDRQAALRKLRYSLHQYNIVGLSTNIDFLLSLSGHPQFEAGNVHTNFI
PQHHDELFPTKKATPHEVMCQAALGLILKEKMLTDAFRDQSDAEFPYFLVCSRMCSWRTV
NILLNKFSPFASSTGRRINICYTRKLSLLDGENIVDVAVSYNQEGSYKMQIQDEMFLISG
EIFNEGDSVYLRSSVNGTVCKSKLVILDNTIYLFFPEGSAQIGLPVPKYLSAVSSVGMQS
GAVAPMTGTVEKVFVKAGDKVKIGDPLMVMIAMKMEHTIRAPKAGVIKKVNFQEGAQANR
HAPLVEFVDEEAESK
NT seq
2208 nt
NT seq
+upstream
nt +downstream
nt
atggcgctggtgctggcggccgagcggggccgctgctgcctctgggcgctgcggcgtcag
cgatggaatcaagtacaaagatttgtgaaatgggcctcaacgataggcggtcacaacata
gggaagattcttattgcaaaccgaggagaaattgcatgcagagtgatgcgaacagcaaag
aaaatgggtgtgaagtctgtagcagtttatagtgaagcagacagaaattcaatgcatgta
gcaatggcagatgaagcatattgcattggtccagcaccctcacagcagagttacttggcc
atggaaaaaataatgcaggtggccaaggtctcagcagcacaggctattcatccaggttat
ggtttcctctcagaaaacacagagtttgcagaattgtgcaagcaagagggaatcatcttc
ataggtccgccttcatctgctatcagagatatgggtattaagagtacttccaaagctata
atgtcggctgctggcgttcctgttgttgaaggttatcatggagaagatcaatcagatgag
tgtctaaaggaacatgccaagagaataggatatccagtaatgattaaagctgttcgtgga
ggtggaggaaagggcatgagaattgctcactcagaaaaggagtttctggaccaactagaa
tcagctaggagagaagcaaagaagtctttcaatgatgatgcaatgctgattgagaaattt
gtagataatccaaggcatgttgaagtccaagtatttggtgaccagcatggcaatgcagtc
tatttgtttgaaagagactgcagtgtgcaaagaagacatcagaagatcattgaagaggca
ccagggccaggaattaatccagaagttcgaaggagacttggagaagctgctgtcaaagca
gctaaagcagtgaattatgtgggagcaggaacagtggaatttattatggactccaaacat
aatttttacttcatggagatgaataccagactgcaagtagagcatccagttacagagatg
atcactggaacagacttggtggaatggcaacttagggttgcagcaggagagaagattccc
ctaatgcaggaagacattgtgctccagggccatgcatttgaagctagaatatatgctgaa
gaccctaataataactttatgccaggggctgggccattgctgcacttaaccaccccacca
cctgatagtttcaccagaatagaaactggagtcagacaaggtgatgaggtttctgttcat
tatgatccaatgattgcaaagctagttgtttgggctgaggatcgtcaagcagcactgaga
aagttgcgatacagtttgcatcaatataatattgtaggattaagcaccaacattgatttc
ttactgagcctgtcgggacacccacagtttgaggctggaaatgtgcacactaatttcatt
cctcaacaccatgatgaactatttccaaccaaaaaggcaaccccacacgaagttatgtgt
caggcagctctaggactcatactgaaagagaaaatgctaacagatgcttttagagatcag
tcagatgctgaattcccatactttcttgtctgttcaaggatgtgttcatggagaacagtc
aatatccttcttaataaattctcaccatttgcatccagcactggtagaagaataaatata
tgttatactagaaaactgtctctgctggatggggaaaacattgtggatgtagctgtaagt
tacaatcaagaagggtcatacaaaatgcagattcaagatgaaatgttcctgatatctgga
gagatcttcaatgaaggtgattcagtttacttgaggtcttcagtaaatggaaccgtgtgt
aagtccaaattggtcattttggacaacaccatttatctcttctttccggaaggtagcgct
cagattggccttcctgtacccaagtacttatctgcagtgagttcagtgggaatgcaaagt
ggtgctgtagcgcccatgacaggcacagttgaaaaggtgtttgtgaaagcaggggataag
gttaagatcggagaccctctaatggttatgatagctatgaaaatggagcataccataagg
gctccaaaggcaggagtgattaaaaaggttaatttccaagaaggtgcccaggccaataga
cacgctccgctagttgaatttgtggatgaagaggccgagtcaaaataa
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