Harpia harpyja (harpy eagle): 128149675
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Entry
128149675 CDS
T10541
Symbol
PIK3CA
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00562
Inositol phosphate metabolism
hhar01100
Metabolic pathways
hhar04012
ErbB signaling pathway
hhar04068
FoxO signaling pathway
hhar04070
Phosphatidylinositol signaling system
hhar04081
Hormone signaling
hhar04140
Autophagy - animal
hhar04150
mTOR signaling pathway
hhar04210
Apoptosis
hhar04218
Cellular senescence
hhar04370
VEGF signaling pathway
hhar04510
Focal adhesion
hhar04620
Toll-like receptor signaling pathway
hhar04625
C-type lectin receptor signaling pathway
hhar04810
Regulation of actin cytoskeleton
hhar04910
Insulin signaling pathway
hhar04914
Progesterone-mediated oocyte maturation
hhar05100
Bacterial invasion of epithelial cells
hhar05132
Salmonella infection
hhar05164
Influenza A
hhar05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
128149675 (PIK3CA)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
128149675 (PIK3CA)
04370 VEGF signaling pathway
128149675 (PIK3CA)
04068 FoxO signaling pathway
128149675 (PIK3CA)
04070 Phosphatidylinositol signaling system
128149675 (PIK3CA)
04150 mTOR signaling pathway
128149675 (PIK3CA)
09133 Signaling molecules and interaction
04081 Hormone signaling
128149675 (PIK3CA)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
128149675 (PIK3CA)
09143 Cell growth and death
04210 Apoptosis
128149675 (PIK3CA)
04218 Cellular senescence
128149675 (PIK3CA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
128149675 (PIK3CA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
128149675 (PIK3CA)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
128149675 (PIK3CA)
04625 C-type lectin receptor signaling pathway
128149675 (PIK3CA)
09152 Endocrine system
04910 Insulin signaling pathway
128149675 (PIK3CA)
04914 Progesterone-mediated oocyte maturation
128149675 (PIK3CA)
09160 Human Diseases
09172 Infectious disease: viral
05164 Influenza A
128149675 (PIK3CA)
05168 Herpes simplex virus 1 infection
128149675 (PIK3CA)
09171 Infectious disease: bacterial
05132 Salmonella infection
128149675 (PIK3CA)
05100 Bacterial invasion of epithelial cells
128149675 (PIK3CA)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hhar04131
]
128149675 (PIK3CA)
Enzymes [BR:
hhar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
128149675 (PIK3CA)
Membrane trafficking [BR:
hhar04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
128149675 (PIK3CA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_rbd
PI3K_C2
PI3K_p85B
DUF2321
ABC1
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
128149675
NCBI-ProteinID:
XP_052661119
LinkDB
All DBs
Position
12:complement(36550829..36601728)
Genome browser
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgcctccacgaccatcatctggtgaactatggggcatccacttgatgccaccgaggatc
cttgtggagtgtcttctcccaaatggaatgatagtgactctagaatgcctccgtgaggcc
accttactaactattaaacatgaactcttcaaagaagcgagaaaataccctctctatcag
ctccttcaagatgaatcttcttacatttttgtaagtgttacacaagaagcagaaagagaa
gaattttttgatgaaacacggagactttgtgacctgcgactatttcagccttttctaaaa
gtcattgaaccagtaggtaacagagaagaaaagattcttaatagagaaataggttttgct
atcggcatgcctgtctgtgaatttgacatggttaaggatccagaagtacaagacttcaga
agaaatattcttaacgtttgtaaagaagcagtggatcttcgagatgccaatgcaccacat
agtagagcgctatatgtctgtcctccaaatgtagagtcttcacctgagctacccaaacat
atatacaataaactagataaagggcaaattatagtggtgatatgggtaatagtctcacca
aacaatgataagcagaaatacaccttaaaaatcaatcatgactgtgtgcctgagcaagtt
attgctgaagcaattaggaagaaaacgcgaagtatgttgctgtcatctgaacaactgaaa
ctttgcgtcttggagtaccagggcaaatatattttaaaagtgtgtggctgtgatgaatac
ttgctagaaaaatatccactgagccagtataagtatataagaagctgtataatgcttggt
cgcatgcccaatctgatgctgatggctaaggaaagcctatatacccagctgccgctggac
acctttacaatgccatcttattccaggcgtatctctacagctacaccctacatgaatgga
gaagctacagccaaatccctctggactataaatagcgctctcagaataagaatcctctgt
gcaacctatgtaaatgtgaacattagagacatagacaagatctatgttagaacaggtatc
taccatggaggggaaccattgtgtgacaacgtgaatactcaaagggtaccttgttctaat
cccagatggaatgaatggctattgtatgacatgtacattcctgatcttccacgtgctgct
cggctctgcctttctatctgttctgttaaaggccggaagggtgctaaagaggagcactgt
ccattggcttggggaaatataaacatgttcgattacacagacactcttgtatctgggaaa
atggctttgaatctttgggcagtacctcatgggctggaggatttgttgaatcctattggt
gttactggatcgaatccaaataaggaaactccatgtttagagctggaatttgattggttt
agcaatcctgtaaagtttccagatatgacggtgattgaagagcatgccaattggactata
tcacgtgaactggggtttaactacagctatgcagggctgagtaacagaatagctagagat
aacgaattaagagaaagtgacaaggaacaactgcgagccatatgtacacgagatcctttg
tctgaaatcactgagcaagagaaggacttcctctggagccacagacactattgcgtgaat
actccagaaattctgcccaaattacttttgtctgttaaatggaattctagagatgaagtg
gcccagatgtactgtttggtaaaagattggcctccaatcaagccagagcaagcaatggag
cttttggactgtaattatccagatccaatggtgcgagcttttgcagttcggtgtctagag
aagtacttgacagacgacaaactgtctcagtacttaatccagctagtacaggttctgaaa
tatgaacagtatttagataatcagcttgtgagatttttacttaagaaggcactgaccaat
caaaggataggacacttcttcttttggcatttaaagtccgaaatgcacaataaaactgta
agtcagaggtttggtttacttctggagtcctattgtcgagcgtgtggcatgtacctaaag
catctgagcaggcaggtggaggctatggagaagctgattaacctcacagatattctcaag
caggaaaaaaaagatgagacccagaaggtacagatgaagtttcttgttgaacaaatgaga
cggccagattttatggatgctttacaaggttttatctctcctcttaatcctgcacatcaa
ctgggaaatcttcggcttgaggagtgcaggataatgtcatctgcaaaaaggccactgtgg
ttgaactgggaaaacccagatattatgtctgaattgttatttcagaacaatgagataatc
tttaaaaatggagacgacttgcgtcaggacatgctgacacttcagataattagaattatg
gaaaacatctggcaaaaccagggtcttgatcttcggatgttgccttatggttgtttgtct
attggtgactgtgtgggactcattgaggtggtgaggagctctcatacgatcatgcaaatt
cagtgtaaaggaggcttgaaaggagcgttgcagttcaacagccatacattgcatcagtgg
ctcaaggacaagaacaaaggagaaatgtatgatgcagctattgacttgttcacacgttct
tgtgccggctactgtgtcgctacctttatactgggcattggtgatcgccacaatagtaac
atcatggtaaaagatgatggacaactgtttcacattgactttgggcacttcctcgatcac
aagaagaaaaaatttggttataaaagagagcgtgtgccatttgtcttaacacaagacttt
ttaatagtgattagtaaaggagcccaagaatgtaccaaaacaagggagtttgaaaggttt
caggagatgtgttacaaggcttatctagcaattcggcagcatgccaatctcttcataaat
cttttctccatgatgcttggctcaggaatgccagaactgcagtcctttgatgatattgca
tacattcgaaagacccttgcattggacaaaactgagcaggaagctcttgagtacttcatg
aagcaaatgaatgatgctcaccatggtggctggacaacaaaaatggactggatcttccac
acaataaagcaacatgctttgaactga
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