Halobacterium hubeiense: Hhub_3052
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Entry
Hhub_3052 CDS
T04202
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hhb
Halobacterium hubeiense
Pathway
hhb00290
Valine, leucine and isoleucine biosynthesis
hhb00660
C5-Branched dibasic acid metabolism
hhb01100
Metabolic pathways
hhb01110
Biosynthesis of secondary metabolites
hhb01210
2-Oxocarboxylic acid metabolism
hhb01230
Biosynthesis of amino acids
Module
hhb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hhb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Hhub_3052 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Hhub_3052 (leuC)
Enzymes [BR:
hhb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Hhub_3052 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
Hhub_3052 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CQH59749
UniProt:
A0A0U5H265
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Position
I:complement(1867806..1869230)
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AA seq
474 aa
AA seq
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MSENTLYDKVWDRHEVTELPTGQTQLFVGLHLIHEVTSPQAFGMLKERDLDVAYPGRTYA
TVDHIVPTADQSRPYSDDAAEEMMSELEENVRAANIDFADPTTGRQGIVHVVGPEQGLTQ
PGMTIVCGDSHTATHGAFGALAFGIGTSQIRDVLATGCVAMEKQKVRRIEVTGELDDGVT
PKDVILQVIRKLGTDGGVGYVYEYGGEAIEDMDMAGRMSICNMSIEGGARAGYVNPDETT
YEYLEGRDRVPDGEEFEELKRYWESIASDADAEYDDVVEIDGDALEPTVTWGTTPGQGIG
ISEEIPAPEDLPADKQDSARAAQEHMDVEPGDTMAGYPIDVAFLGSCTNARLPDLREAAE
VVKGHEVHDSVRAMVVPGSQRVKAAAEAEGLDEVFEDAGFDWRGAGCSMCLGMNEDQLVG
DERCASSSNRNFVGRQGSKDGRTVLMSPPMVAAAAITGEVTDVRELERFEEVRA
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgagtgagaacacgctctacgacaaggtctgggaccgccacgaggtcacggagctgccg
accgggcagacccagctgttcgtcggcctccacctcatccacgaggtgacgagcccgcag
gcgttcgggatgctcaaggagcgcgacctcgacgtcgcgtaccccgggcgcacgtacgcg
accgtggaccacatcgtcccgaccgccgaccagtcgcgcccctacagcgacgacgcggcc
gaggagatgatgagcgaactggaggagaacgtgcgcgcggcgaacatcgacttcgccgac
ccgacgaccggccggcagggcatcgtgcacgtagtcggcccggagcaggggctcacccag
cccgggatgaccatcgtctgtggggactcccacacggcgacccacggcgcgttcggcgcg
ctcgcgttcggcatcggcacctcccagattcgggacgtgctggcgaccggctgcgtcgcc
atggagaagcagaaagtgcgtcgcatcgaggtcactggcgaactcgacgacggcgtgacg
ccgaaggacgtcatcctgcaggtcatccggaagctcggtaccgacggcggcgtcggctac
gtctacgagtacggcggtgaggcaatcgaggacatggacatggccggtcggatgagcatc
tgcaacatgtccatcgagggcggcgctcgcgcgggctacgtcaaccccgacgagaccacc
tacgagtacctcgaaggccgcgaccgcgtccccgacggcgaggagttcgaggagctcaag
cgctactgggagtccatcgcctccgacgcggacgccgagtacgacgacgtcgtggaaatc
gacggcgacgcgctcgaacccacggtcacgtgggggacgacgcccggccagggcatcggc
atctccgaggagattcccgcgcccgaggacctgcccgcggacaagcaggacagcgcgcgc
gccgcgcaggaacacatggacgtcgagcccggcgacacgatggcgggctaccccatcgac
gtggcgttcctcgggagctgcacgaacgcgcgcctgccggacctccgggaggccgcggag
gtcgtgaagggccacgaggtccacgactccgtgcgcgcgatggtcgtgccgggcagccag
cgcgtcaaagccgccgccgaagccgagggcctcgacgaggtgttcgaggacgccggcttc
gactggcgcggcgccggctgttcgatgtgtctcgggatgaacgaggaccagctagtcggc
gacgagcggtgcgcgtcctcgtcgaaccggaacttcgtcggccggcagggctccaaggac
ggccgcaccgtcctgatgagcccgccgatggtcgccgcggccgccatcaccggcgaggtc
acggacgtccgcgaactggagcgcttcgaggaggtgcgcgcatga
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