Halobacillus halophilus: HBHAL_2575
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Entry
HBHAL_2575 CDS
T02031
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hhd
Halobacillus halophilus
Pathway
hhd00290
Valine, leucine and isoleucine biosynthesis
hhd00660
C5-Branched dibasic acid metabolism
hhd01100
Metabolic pathways
hhd01110
Biosynthesis of secondary metabolites
hhd01210
2-Oxocarboxylic acid metabolism
hhd01230
Biosynthesis of amino acids
Module
hhd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hhd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HBHAL_2575 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HBHAL_2575 (leuC)
Enzymes [BR:
hhd01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HBHAL_2575 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
HBHAL_2575 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CCG44921
UniProt:
I0JLA1
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All DBs
Position
1584131..1585543
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AA seq
470 aa
AA seq
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MSQPKTIIEKVWDQHVVHKEEGKPNLLYIDLHLIHEVTSPQAFEGLRLSGRKVRRPDLTY
ATMDHNVPTIHRNVIKDQISKKQMETLEENCEEFGISLADINHPDQGIVHVIGPELGLTQ
PGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQSIWQAPPKTLQVHIDGKLGTGVT
AKDLILAVIGRFGVRFGTGHVIEYTGEAIRNLSMEERMTICNMSIEAGARAGLISPDETT
VEYLRGKRYVPEGEEFDKAAQQWLNLASDPGARYDMELEIHADEIEPQVTWGTNPSHCVP
VSAQVPDPLDAETDDEKDSIERALEYMGLEANQTIQSIPIEHVFIGSCTNSRISDLRKAA
DIVKGGHVHEGIRALVVPGSQSVKLAAEEEGLDKIFIDAGFEWRDAGCSMCLAMNDDIVP
PGERCASTSNRNFEGRQGNGARTHLVSPEMAAAAALEGRFVDVRKQMSTV
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
ttgagtcaaccgaaaacaattattgaaaaagtttgggatcagcatgtcgttcataaagaa
gaagggaagccgaacctcctctatatcgacttgcacctgattcatgaggtaacctctccc
caggcgtttgagggtctgcgcctgagcgggaggaaagtccgccggccggacctgacgtat
gccaccatggatcataacgttccgaccattcaccgaaacgtgattaaagaccagatttcc
aagaagcagatggagacacttgaagaaaactgtgaagaatttggcatcagcctggccgat
attaatcacccggatcaagggattgtccacgttatcgggccggagcttggattaacccag
cctggcaaaaccattgtctgcggtgacagccatacgtcaactcacggagcttttggtgca
ttagccttcgggatcggtacgagtgaagtggaacacgtgcttgccacccagtcgatctgg
caggcgcctccgaagacgcttcaggttcatatcgatggcaagttaggaacaggcgtaaca
gcgaaagacttaatccttgccgttattggccgtttcggtgttcggttcggaactggacac
gtcattgaatatacaggtgaagcgatccgtaacttgtccatggaagaacgaatgacgatt
tgcaacatgtcgattgaagcaggcgcaagagctggattgatcagcccggatgagacgaca
gtcgagtacttgagaggaaaacgttacgtgccggagggagaagagttcgataaagctgcc
cagcagtggctgaacctggcatctgatccaggcgcccggtacgatatggagcttgaaatt
catgccgatgaaatcgaaccgcaagtcacatggggaacaaacccttctcattgtgtaccg
gtctccgcacaagtaccggatccactcgatgccgaaacagatgatgaaaaagacagcatc
gagcgtgccctggagtacatggggctggaagcgaatcaaaccattcagtccatccctatt
gagcatgtctttatcggttcctgcaccaactcaaggatcagcgacttgagaaaagccgct
gatattgtgaaaggcggccacgtccacgaaggaatcagagccctggttgtaccaggctct
caatccgtgaaactggcagctgaagaagaaggactggataaaatattcatagacgccggt
ttcgaatggagagacgcaggctgcagtatgtgtctggcgatgaatgacgacatcgtaccg
ccgggcgaacgctgcgcctcgacctcaaaccggaactttgaaggacgtcagggtaatgga
gccagaacccatctggtcagtccagaaatggcagcagcagctgcactggaaggccgcttc
gtagacgtcagaaaacagatgagtaccgtttag
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