Halobacillus halophilus: HBHAL_2873
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Entry
HBHAL_2873 CDS
T02031
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hhd
Halobacillus halophilus
Pathway
hhd00300
Lysine biosynthesis
hhd00550
Peptidoglycan biosynthesis
hhd01100
Metabolic pathways
hhd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hhd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HBHAL_2873 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HBHAL_2873 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HBHAL_2873 (murF)
Enzymes [BR:
hhd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HBHAL_2873 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
BtrH_N
EspB_PPE
Motif
Other DBs
NCBI-ProteinID:
CCG45221
UniProt:
I0JM51
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All DBs
Position
1869726..1871087
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AA seq
453 aa
AA seq
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MILEVQELTTLFPEFKGAAQDRITLREVLTDTRVEAKQSLFIPIVGENFDAHDFIKDAIK
QGAVAALWQKDKDLPYAVPTDFPVFFVEDTTKGLQEVAEYYLQKVRPLVIGITGSNGKTT
TKDMTASVLSRKYKTHKTAGNYNNHIGLPLTILAMKEDTEVLVLEMGMDRAGEISVLSKL
AHPKYAIITNIGESHIENLGSREGIASAKLEIKDGMSEDGALIIDGDEPLLHAVKLDERS
LSCGFDSTSDTQVKIISTSDDASEFKVNEKETYNLPLAGKHNVKNASYVITLAKKAGLSN
DQIQEGFDHLQMSSMRYEKHIGINESLIINDAYNASPTSMKALIEVMAQLTTKSRKVLIL
GDMFELGSQSRVLHRSVAEAVTDKIHAVYTIGEHSEEISRAVAERQPQIATKHFTDKETL
SHHVRAALTADTVVLIKASRGMKLEELLNDLVK
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgattttagaagtgcaagaactgactaccctcttccctgaatttaaaggagcggcacaa
gacagaattacattaagagaagttctaaccgacacaagagtggaagctaagcagagtttg
tttatacctatagtgggtgagaattttgatgcccatgattttataaaggacgcgattaaa
caaggggcggtcgcagcactctggcagaaggataaagatcttccttacgccgtaccgacc
gatttccctgtcttttttgttgaggatacaacgaaaggacttcaggaagtggcggagtat
tatttgcagaaggttcgtcctttagtcattggaataaccggctccaatggaaagacaacg
acaaaggatatgacggcttccgtgttaagccggaagtataagacgcataaaacagctgga
aactataataatcatatcggacttcccttaacgatccttgccatgaaggaggatacagaa
gttctcgtcctggaaatggggatggaccgggcgggtgagatctccgtcttatcaaaactt
gctcatcctaaatatgccatcataacaaatattggtgaatctcatattgaaaaccttggc
tcccgtgagggcatcgcttctgctaagctggaaatcaaggatgggatgtcagaggatggt
gcgttaatcattgatggggatgaaccgctgttacatgccgtcaaactggatgaaagatca
ctatcatgcgggttcgatagcaccagcgatacccaagtgaagataatcagcacttcagac
gatgccagtgaattcaaggttaatgaaaaagaaacttataatcttcctctcgctggaaag
cataatgtgaaaaatgcgtcttacgtcattactcttgcaaaaaaagcaggactgtccaat
gatcaaattcaagaaggctttgaccatcttcagatgtcgagcatgcgttatgaaaaacat
atcggaataaatgaatctttaattataaatgacgcctacaatgcctcgccgacctcaatg
aaggctctgatagaagtgatggctcaactaactacgaagtctcgcaaggttctgattctc
ggggatatgtttgaacttgggtcacagtcccgcgttttacaccgcagtgtagctgaagcc
gttaccgataaaattcatgccgtttataccattggcgagcattccgaagaaatatccagg
gcggtcgctgaacggcagccacaaatagcaacaaagcattttacagataaagaaacttta
agtcatcatgtacgtgcagcattaacggccgataccgtagttcttattaaagcttcgaga
ggaatgaagctggaggaattactgaacgatctcgtaaaatga
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