Halomonas hydrothermalis: CLM76_14840
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Entry
CLM76_14840 CDS
T05117
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
hhh
Halomonas hydrothermalis
Pathway
hhh00280
Valine, leucine and isoleucine degradation
hhh00640
Propanoate metabolism
hhh00785
Lipoic acid metabolism
hhh01100
Metabolic pathways
hhh01110
Biosynthesis of secondary metabolites
hhh01210
2-Oxocarboxylic acid metabolism
Module
hhh_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hhh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
CLM76_14840
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
CLM76_14840
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CLM76_14840
Enzymes [BR:
hhh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
CLM76_14840
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Motif
Pfam:
E1_dh
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ATH78783
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Position
3172178..3173380
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AA seq
400 aa
AA seq
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MTQFVHQPTFMTGDEFSIDTFSVLSPEGELHEGADEPALSRDHARRLYQAMLATRILDER
MMAAQRQGRLSFYMQCTGEEAAVVGATAALDDADMIMAQYREQGALMYRGFSIDEFMNQL
FGNELDYGKGRQMPIHYGSRKLHYMTISSPLATQIPQATGYAYGQKLAGEGHCTLTFFGE
GAASEGDFHAALNMASVHQVPVIFFCRNNGYAISTPATEQFAADGIAPRAFGYHMHVIRV
DGNDALAVFEATRQARKIAVEQHQPVLIEAMSYRLAAHSSSDDPSGYRAKSEEEAWRVKD
PLLRMQRWLVSKGWWSDDEEARQQESLRREVLETMKRAEKRPPPPLDSLITDVYADVTPA
LQRQLDQLKRHIRRYPDAYPRGAQSLDPSVSTAHDAQGDA
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atgactcagttcgtacatcagccgaccttcatgaccggcgacgaattctccatagacacc
ttcagcgtgctcagccccgagggcgagctccatgaaggtgccgacgagcccgccttgagc
cgcgaccacgcccgcaggctttatcaggccatgctggccacgcgtattctcgatgagcgc
atgatggctgcgcagcgccagggcaggctcagcttctacatgcagtgtaccggtgaggag
gccgcggtggtgggagccaccgcagccttggacgatgccgacatgatcatggcgcagtac
cgcgaacagggcgcactcatgtatcgcgggttctccatcgacgagttcatgaatcagctg
tttggcaacgagctggactatggcaagggtcggcagatgccgatccactatggttcccgc
aagctgcattacatgaccatctcttcgccgctggccactcagattccccaggcaaccggc
tatgcctatggccagaagctcgcaggtgaaggccactgtaccctgacgttcttcggtgaa
ggggctgcctcggaaggcgacttccacgccgccctgaacatggcctcggtgcatcaggtg
ccggtcattttcttctgtcgcaacaatggctatgccatctcgactcccgccaccgaacag
tttgccgccgatggcattgccccgcgtgcgttcggctatcacatgcatgtcatccgcgtg
gatggcaacgacgccctggcagtcttcgaagccacccgccaggcgcgcaagatagccgtg
gagcagcatcagccggtgctgatcgaagccatgtcgtaccgcttggcggcgcactcctcc
tcggacgacccgtcgggctatcgtgccaagagcgaggaggaggcgtggcgagtcaaggac
ccgctattgcgcatgcagcgctggctggtgagtaaaggatggtggagcgacgacgaagag
gcccgccagcaggagagcctgcggcgggaagtgctggagaccatgaagcgcgccgaaaag
cgtccgccgccgccgctggactccttgatcaccgatgtctatgccgacgtgacgcctgcc
ttgcagcgccagctggatcagttgaaacggcacattcgccgctatcccgatgcctatccg
cgcggcgctcagtcgctggaccctagcgtatcgacggcccacgacgcacagggagatgcc
tag
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