Hippoglossus hippoglossus (Atlantic halibut): 117752879
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Entry
117752879 CDS
T07778
Symbol
top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
hhip
Hippoglossus hippoglossus (Atlantic halibut)
Brite
KEGG Orthology (KO) [BR:
hhip00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hhip03032
]
117752879 (top2a)
03036 Chromosome and associated proteins [BR:
hhip03036
]
117752879 (top2a)
Enzymes [BR:
hhip01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
117752879 (top2a)
DNA replication proteins [BR:
hhip03032
]
Eukaryotic type
DNA Topoisomerases
117752879 (top2a)
Chromosome and associated proteins [BR:
hhip03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
117752879 (top2a)
Centrosome formation proteins
Centriole proteins
117752879 (top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
117752879
NCBI-ProteinID:
XP_034426493
LinkDB
All DBs
Position
19:11828251..11841820
Genome browser
AA seq
1580 aa
AA seq
DB search
MSDPLKQTFFENKPLEKTKKDPKRMSVERIYQKKTQLEHILLRPDSYIGSVEPVTQQMWV
YDEGVGMNCRDVMFVPGLYKIFDEILVNAADNKQRDKRMSTIKVNIDVENNTISVWNNGK
GIPVVQHKVEKVFVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETAC
KESKKYFKQTWYDNMGRTEDANIKPFEGEEYTCITFRPDLAKFKMSILDKDTVALMTRRA
YDIAGAAKGVRVFFNGKKLPVTDFRSYVDMYVKDKVDELGQALTIIHESLAGRWEVCLTM
SEKGFQQVSFVNSIATTKGGRHVDYVAEQVVGKLIEVVKKKNKAGVTVKPFQVKNHMWLF
VNCLIENPTFDSQTKENMTLQHKNFGSTCHLTDKFIKQATSCGIVESIMNWVKFKAQSQL
NKKCSAVKHTKIKGVPKLDDANDAGGRNSISCTLILTEGDSAKTLAVSGLGVVGRDRYGV
FPLRGKMLNVREATHKQIMENAEINSIIKILGLQYKKNYSDPESLKTLRYGKLMIMTDQD
LDGSHIKGLLINFIHHNWPSLLRHNFLEEFITPIIKASFKKSQQSFYSIPEFDEWKESQA
NHKSWKIKYYKGLGTSTSQEAKEYFCDMERHRIPFKYSGPEDDEAITLAFSKKKVDERKE
WLTNFMNNRRQRREHNLPEDYLYGQATKSLSYNDFVNKELVLFSNSDNERSLPCLVDGLK
PGQRKVLFCCFKRNDKREVKVAQLAGSIAEMSAYHHGEVSLMMTIVGLAQNFVGSNNMNL
LQPQGQFGTRLHGGKDSASPRYIFTMLSPLARLVFPPVDDNLLKYNFDDNQRVEPEWYMP
IIPTVLVNGSEGIGTGWASRIPNFNIREIVTNIHRMLNGEEPLPMLPNYKGFKGTIEQVL
DNQYMNTGEVAIIDSTSIEISELPVKTWTQTYKENVLEPMLNGTEKAPPLITDYREYHTD
TTVRFVVQMTEEKLREAEAAGLHKVFKLQSPLTCNSMVLFDHVGSLKKYESVQDILKDFF
ELRMKYYLLRKDWLVGMLGAESARLTNQARFILEKIEGTLVIENKPKKELIRMLQEMGYD
SDPVKAWKQAQEKNEEELEEGEEEEGAEKEDPSAPDYNYLLSMPMWFLSKEKKEELCKQR
DAKMTELSTLKKKIPADLWREDLAAFSEELVRVEAKEKESNIMPATKGTGKGRAVKVKVK
QETLPTPQGRRVIPRVTSAMKAEANKKADLKKGEGKRGKKIKSEDVVLKMEFGDDAENAE
PDEELGLAARLEKKTKTQSKEKAASKIGKQTTIQFKPVAKKPKKDPWSENESEDLSNGDA
EEVVAARERVERKTKSAVKYSVSDSEDDFDDWGKKDAPKGKAVISSDDDSFAPDPSTMVD
SEMDSPAPPPKVPEPAKKVTECKSTVKKAETKSSSQSDDQVPASKAPVQRKTKEAAPKKA
AAAKKPAAPKKKAADAKQPSILDALSKPKPSSKTAAKPIPSFDSSDSEADVKVTMAKPVL
KRKQVVSSDSDCSSDNLMSRLMTKTKAGSKKTKKWDEDDSFQVSDQEAAEPPKATAPREK
PSRGRKPVTYILDSDSDEDF
NT seq
4743 nt
NT seq
+upstream
nt +downstream
nt
atgtcggacccactgaagcaaacgttctttgagaacaagccgctggaaaagacaaagaaa
gatcccaagaggatgtcggtggagaggatctatcagaagaagactcagctggagcacatc
ttgctccggccggactcctacataggctcagtggagcctgtcacccaacaaatgtgggtg
tatgatgagggtgttggaatgaactgccgtgatgtcatgtttgttcccggtctttacaag
atttttgatgagatccttgttaatgcagctgacaataagcagagggacaagcgcatgtcc
accatcaaagtcaatattgatgttgaaaacaacaccatcagtgtgtggaataatgggaag
ggtattcctgtggtgcagcacaaggtggagaaggtctttgtgcctgcgctcatcttcgga
cagctcctcacctccagtaactatgatgacgacgagaagaaagtcaccggtggacgtaat
ggatatggtgcaaagctttgcaatatcttcagcacaaagttcactgtggagactgcctgt
aaagagtcaaagaaatacttcaagcagacttggtacgacaacatgggcaggacagaagat
gctaacatcaaaccctttgaaggagaggaatacacatgcatcaccttcaggccagatcta
gccaagttcaagatgagcatcttggacaaagatacggtggcactaatgaccaggagggcc
tacgacattgctggagccgctaagggtgtccgtgtgttcttcaatggcaagaagctgcca
gttacggacttccgaagctacgtggacatgtatgtgaaggacaaggtggatgagcttggt
caggccctcaccatcatccacgagtctttggctgggcgctgggaggtctgcctcaccatg
agcgagaagggtttccagcaagtcagctttgtcaacagtattgccacgaccaagggcggg
aggcacgtcgactatgtggctgaacaggtggtcgggaagcttattgaagtggtgaagaaa
aagaacaaagctggggtgaccgtcaagccttttcaggtgaagaaccacatgtggctgttt
gtcaactgcctgattgagaaccccacctttgactctcagaccaaagagaacatgacactg
cagcacaagaactttggatccacctgtcatctcactgacaagttcatcaaacaggccaca
tcctgtgggattgtggaaagtataatgaactgggtgaagttcaaagctcaatcgcagctc
aataagaaatgctcagctgtcaagcacacaaaaatcaaaggggtgccaaaactagatgat
gctaatgatgcaggtgggaggaactccattagctgcacgctgatccttactgagggagac
tcagccaagacactggctgtgtctgggctcggagttgtcggcagggaccgctatggcgtc
tttccactgagggggaaaatgctcaatgtccgggaggccactcacaaacagattatggag
aacgccgagataaacagcatcattaagatcctcggccttcagtacaagaagaactacagc
gacccagaatccctcaagactctgcgttatggcaagctcatgatcatgacagatcaggat
ctagatggctcccacattaagggcttgctgatcaacttcatccaccataactggccgtct
ttgctgcgccataacttcctggaagagttcatcacccccatcatcaaggcgtctttcaag
aaaagtcagcagtctttctacagtatccctgagttcgatgagtggaaggaaagtcaggcc
aaccacaaatcttggaaaatcaaatactacaaaggtttgggaaccagcacatcgcaggaa
gccaaggagtatttctgtgatatggagagacaccgtatcccattcaagtactctggtcct
gaagacgatgaagctatcacccttgcctttagcaaaaagaaagtggatgagcggaaagaa
tggctgaccaatttcatgaacaacaggcgccagcgcagagagcacaacctgcctgaggac
tacctgtacggtcaggccacaaagtccctctcctataacgactttgtcaacaaggagctg
gtactgttctccaactctgacaacgagaggtcacttccctgcctggtggatggtcttaag
cctggccagaggaaggtgttgttctgttgcttcaagagaaacgacaagcgtgaagtcaag
gtggcccagttggctggctcaattgctgagatgtctgcgtaccaccatggagaggtctct
ctgatgatgaccattgttggtttggcccagaactttgtgggaagcaacaacatgaacctg
ctgcagcctcagggtcagtttggaaccaggttgcacggtggcaaggactctgccagccct
cgttacatcttcaccatgctcagccctctggcccgccttgttttcccacctgtggacgac
aacctgctcaagtacaactttgatgacaaccagcgcgtggagccagagtggtacatgccc
atcatccccactgtgctggtgaatggatccgagggtatcggcacaggctgggccagcagg
atcccgaacttcaacataagagagatcgtcaccaacatccaccgaatgctcaacggcgag
gagccgctgcccatgcttccaaactacaaaggcttcaaaggcacaattgagcaggtgttg
gacaaccagtacatgaacaccggcgaggtcgccatcattgattccaccagcatcgagata
tctgaattgcccgtcaaaacctggacacagacctacaaggagaacgtgctggagccaatg
ttgaatggcacagagaaggctcctcctctgatcaccgactacagggagtaccacaccgac
accactgtgcgctttgtggtccagatgacagaagagaagctgagggaggcggaagctgcc
ggcctccataaagtcttcaaactgcagagtcccctcacctgcaattctatggttctgttt
gaccatgttggcagcctgaagaagtacgagtctgtgcaggatattctcaaggacttcttt
gagttgaggatgaagtactatttgctgagaaaggactggttggtcggcatgctgggggca
gagagcgccagactcaccaatcaggcccgcttcatcctggagaaaatcgagggcaccctg
gtcattgagaacaagccaaagaaggagctgatccgcatgctgcaggagatgggctacgac
tcagacccagtcaaggcttggaaacaggctcaagagaagaatgaggaggagctggaggag
ggtgaggaggaggaaggagcagagaaggaagaccccagtgcgccggattacaactaccta
ctcagcatgcccatgtggttcctgtccaaagagaagaaggaggagctgtgcaaacagagg
gatgctaagatgaccgagctgagcaccctgaagaagaagattccagcagacttatggagg
gaagaccttgctgctttctctgaggaactagtgcgcgttgaggcaaaagaaaaggagagt
aacatcatgcctgccacaaaggggactggaaaaggcagagccgtgaaggtgaaggtgaag
caggagactctgcccactccccagggccgccgcgtcatcccacgggttaccagtgccatg
aaagctgaggccaacaagaaggctgatctcaagaaaggagaaggcaagaggggcaagaag
atcaagagtgaagatgttgtgttgaagatggagtttggcgacgatgcagagaacgcagag
ccagatgaggagcttggcttggctgcacgactggaaaagaaaacaaaaactcagtcaaaa
gaaaaagccgcatcaaagataggcaagcagaccaccattcagttcaagcctgttgccaag
aagcccaagaaggacccgtggtcggagaacgagtctgaagatctgtccaatggtgacgcg
gaggaggtggttgccgccagggaacgcgttgagcgtaaaactaaatctgcagtaaagtac
agcgtctctgacagtgaagatgactttgatgactgggggaagaaggatgctccaaaaggg
aaagcggttatcagtagtgacgatgacagcttcgccccagaccccagcaccatggtcgac
agcgaaatggactctccagcgccaccacccaaagtcccagaacctgcgaagaaagtgaca
gagtgcaaatcaactgtgaaaaaggctgagaccaagtcaagctctcagtccgatgatcag
gtgcctgcgtccaaggctccagttcaacgcaaaaccaaagaggctgcgcccaagaaagct
gcagctgccaagaaaccagctgctcccaagaagaaggctgcagatgcgaagcagccgtcg
atcctggacgctctctctaagcccaaaccttcctccaaaactgctgccaagcccatccct
tcgtttgactccagtgattcagaagctgatgttaaagttacaatggcgaagcccgttctc
aagcggaaacaagtcgtcagctccgactccgactgcagctccgacaacctcatgtcacgc
ctcatgaccaaaacgaaggccggcagcaagaaaacgaagaaatgggacgaggatgacagc
ttccaggtttcagatcaggaggcggcagaacctcccaaagccacagcaccgcgggagaag
ccctcacgtggccgcaaacctgtgacctacattctggactctgactcagatgaagacttt
taa
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