Hippoglossus hippoglossus (Atlantic halibut): 117772586
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Entry
117772586 CDS
T07778
Symbol
bace1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
hhip
Hippoglossus hippoglossus (Atlantic halibut)
Brite
KEGG Orthology (KO) [BR:
hhip00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hhip01002
]
117772586 (bace1)
Enzymes [BR:
hhip01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
117772586 (bace1)
Peptidases and inhibitors [BR:
hhip01002
]
Aspartic peptidases
Family A1: pepsin family
117772586 (bace1)
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Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
117772586
NCBI-ProteinID:
XP_034459724
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Position
13:24770120..24784655
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AA seq
513 aa
AA seq
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MEASSLRGALVILSAMCCLSCGHSAPEASGLPRAIRVPLRQGARSEPLLPLPPAAGRHAA
RRRRGAAASGISFVDMIDNLRGKSGQGYYVEMAVGSPPQKLNILVDTGSSNFAVGAAAHP
FLHRYYHRSLSSSYNDLGRSVYVPYTQGRWEGELGTDLVSVPHGPNASLRANIAAITQSD
RFFINGSNWEGILGLAYADIARPDETLEPFFDSLVRQTPVPNLFSLQLCGAGYTQNDFLG
SATVGGSMIIGGVDKSLHVGELWYTPIRREWYYEVIIVRIEVNGQDLNMDCKEYNYDKSI
VDSGTTNLRLPRKVFQAAVKAIEAASSTEQFPSGFWLGEQLVCWQVGTTPWHIFPVISLY
LMSENRNQSFRISILPQQYLRPVEDVASAQEDCYKFAVSQSSTGTVMGAVIMEGFYVVFD
REKKRIGFAVSTCHVHDEFRTASVEGPFHGVDLEDCGYNIPQTDESTLMTIAYIMAGICA
LFMLPLCLMVCQWRFARCLHPHGDFADDISLLK
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atggaggcgtcgtcgttacggggcgctctggttatattgtcggctatgtgctgcctcagc
tgcggtcactcggcgccggaagcctcgggcctgcctcgggccatccgcgtgccactgcgg
caaggcgctcgctctgaaccgttactgccgctgccgcctgccgcggggagacacgcggcg
cggcgcaggagaggagcggcagcgagcggcatcagcttcgtggatatgatcgataacctg
cgggggaagtccggacagggatactacgtggagatggccgtgggttctcctccgcagaag
ctgaacatattggtggatacaggaagcagtaactttgctgtcggggcggctgcacatccc
tttctgcacagatactaccatcgctcactctccagctcatacaatgacctcggaaggagc
gtgtacgttccttacacccaaggccgctgggaaggggagctgggcactgacctagtctct
gtcccacatggccccaacgccagcctgcgtgccaacattgctgcaatcacccagtcagat
cgcttcttcatcaacggatccaactgggagggaatcctgggactggcctacgctgacata
gcccggcctgatgagacattggagcctttctttgactctctggttcgtcagacccctgtc
cccaacctcttctctctccagctgtgtggagctggctacacccaaaacgacttcctcggc
agcgctactgttggtggcagcatgatcatcggtggagtggacaaatcactgcacgtagga
gagctttggtacactcctatccgcagggaatggtattatgaggtcatcatcgtacgtatt
gaggttaatgggcaggacctcaacatggactgtaaagagtacaactatgataagagtatt
gtagacagtggcaccaccaaccttcggctgcctagaaaagtcttccaggctgcagtcaag
gctattgaagctgcctcttcgactgaacagtttccctctggattctggctgggggagcag
ctggtatgttggcaggtcggcactacaccctggcacatcttcccagttatctccctatac
ctgatgagtgaaaaccgcaaccagtccttccggatctccatcctaccgcagcaatacctg
aggccagtagaggatgtggcttcagcccaagaggactgctataaatttgccgtttcccag
tcgagcactggaacagtgatgggggctgtcatcatggagggcttttacgtggtctttgac
cgtgagaagaagagaattggctttgctgttagcacttgccatgtacacgatgagtttcgc
acagcctctgtggagggcccattccacggcgttgacctggaggactgcggctacaacatc
cctcagacggacgagtccactctcatgaccatcgcctacatcatggccggaatctgtgct
ctcttcatgctgccgctgtgtctcatggtgtgccagtggcgcttcgcccgttgcctccac
ccacacggggactttgctgatgacatatcgctcctaaagtga
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