Hippoglossus hippoglossus (Atlantic halibut): 117773246
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Entry
117773246 CDS
T07778
Symbol
bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
hhip
Hippoglossus hippoglossus (Atlantic halibut)
Pathway
hhip00280
Valine, leucine and isoleucine degradation
hhip00640
Propanoate metabolism
hhip00785
Lipoic acid metabolism
hhip01100
Metabolic pathways
hhip01210
2-Oxocarboxylic acid metabolism
Module
hhip_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hhip00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
117773246 (bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
117773246 (bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
117773246 (bckdha)
Enzymes [BR:
hhip01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
117773246 (bckdha)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
117773246
NCBI-ProteinID:
XP_034460881
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All DBs
Position
13:3446355..3452390
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AA seq
446 aa
AA seq
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MAAVSGVNKMYGACFQAVRVATGLRATRLLQHRSLRVSAVHQQQPFDSSLDKPQFPGASA
EYVDQLEFIQPNVISGIPVYRVMDRQGNIINPSEDPQLSKETVMNFYQKMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHIGSAAALDPSDLVFGQYREAGVLMYRGFPLDLFMAQCY
ANADDLGKGRQMPVHYGSKDLNFVTISSPLATQIPQATGAAYAFKRENTNRAVICYFGEG
AASEGDAHAGFNFSATLECPIIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGMLSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYMTARDWWSEDDERSWRKQSRKTVMEAFEKAERRLKPNPELMFTDVYQEMTPN
LDRQRQSMWRHMQQYKEHYPLDLYDK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggctgtgagcggcgtcaacaaaatgtacggagcgtgtttccaggctgttcgtgtg
gcgacaggactgagggcgacgaggctgctgcagcacaggagcctgcgagtcagcgccgtg
caccagcagcagccctttgactcatcgctggacaagccgcagttccctggagcgtctgcc
gagtatgtggatcagcttgagtttatccagcccaatgtgatctctgggatcccagtgtac
cgggtgatggacaggcaaggaaatatcatcaacccctctgaagaccctcagctctccaaa
gagacggttatgaacttttatcagaagatgactctgctgaacacgatggaccgcattctc
tatgagtcccagagacagggacggatttccttctacatgaccaactatggtgaggaggga
acacacattggcagtgctgctgctcttgacccaagtgacctggtctttggtcaatacaga
gaagcgggagtgttgatgtatcgcggttttcctctggatctgttcatggctcagtgctat
gccaatgctgatgacctcggcaagggtcggcagatgcctgtccactacggctccaaagac
ctgaactttgtcaccatctcctctcctctggccactcagattcctcaggcgactggagct
gcatatgcattcaagagagaaaacaccaaccgcgctgtgatctgttatttcggagaggga
gccgccagtgaaggggacgcacacgctggcttcaacttctctgccaccctagagtgccca
attattttcttctgtcgtaacaacggctacgccatctccacccccaccaacgagcagtac
agaggggacggcattgctgctcgtggtccaggctacggaatgctgtccatccgtgtcgat
ggtaacgatgtgtttgccgtgtacaacgctacgaaggaagctcgacgcagagctgtggca
gagaaccagcctttcctcatcgaagcaatgacgtacagaattgggcaccacagcaccagc
gacgacagctcggcttaccgctcagtggacgaggtgaactactgggacaagcaggaccac
cccatctccaggctgagacactacatgacggcccgcgactggtggagcgaagacgacgag
aggagctggaggaagcagtcccgtaagacggtgatggaggcgttcgagaaggctgaacgg
cgcctgaagcccaatcccgaactcatgtttactgacgtgtaccaggagatgacgcccaac
ctggacaggcagagacaatccatgtggaggcacatgcagcagtacaaggagcactaccca
cttgacctgtatgataaataa
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