Hippoglossus hippoglossus (Atlantic halibut): 117779227
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Entry
117779227 CDS
T07778
Symbol
zgc:158659
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
hhip
Hippoglossus hippoglossus (Atlantic halibut)
Pathway
hhip00562
Inositol phosphate metabolism
hhip01100
Metabolic pathways
hhip04012
ErbB signaling pathway
hhip04068
FoxO signaling pathway
hhip04070
Phosphatidylinositol signaling system
hhip04081
Hormone signaling
hhip04140
Autophagy - animal
hhip04150
mTOR signaling pathway
hhip04210
Apoptosis
hhip04218
Cellular senescence
hhip04370
VEGF signaling pathway
hhip04510
Focal adhesion
hhip04517
IgSF CAM signaling
hhip04518
Integrin signaling
hhip04620
Toll-like receptor signaling pathway
hhip04625
C-type lectin receptor signaling pathway
hhip04810
Regulation of actin cytoskeleton
hhip04910
Insulin signaling pathway
hhip04914
Progesterone-mediated oocyte maturation
hhip05100
Bacterial invasion of epithelial cells
hhip05132
Salmonella infection
hhip05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
hhip00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
117779227 (zgc:158659)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
117779227 (zgc:158659)
04370 VEGF signaling pathway
117779227 (zgc:158659)
04068 FoxO signaling pathway
117779227 (zgc:158659)
04070 Phosphatidylinositol signaling system
117779227 (zgc:158659)
04150 mTOR signaling pathway
117779227 (zgc:158659)
09133 Signaling molecules and interaction
04081 Hormone signaling
117779227 (zgc:158659)
04517 IgSF CAM signaling
117779227 (zgc:158659)
04518 Integrin signaling
117779227 (zgc:158659)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
117779227 (zgc:158659)
09143 Cell growth and death
04210 Apoptosis
117779227 (zgc:158659)
04218 Cellular senescence
117779227 (zgc:158659)
09144 Cellular community - eukaryotes
04510 Focal adhesion
117779227 (zgc:158659)
09142 Cell motility
04810 Regulation of actin cytoskeleton
117779227 (zgc:158659)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
117779227 (zgc:158659)
04625 C-type lectin receptor signaling pathway
117779227 (zgc:158659)
09152 Endocrine system
04910 Insulin signaling pathway
117779227 (zgc:158659)
04914 Progesterone-mediated oocyte maturation
117779227 (zgc:158659)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
117779227 (zgc:158659)
09171 Infectious disease: bacterial
05132 Salmonella infection
117779227 (zgc:158659)
05100 Bacterial invasion of epithelial cells
117779227 (zgc:158659)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hhip04131
]
117779227 (zgc:158659)
Enzymes [BR:
hhip01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
117779227 (zgc:158659)
Membrane trafficking [BR:
hhip04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
117779227 (zgc:158659)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_rbd
PI3K_p85B
ABC1
DUF2321
Motif
Other DBs
NCBI-GeneID:
117779227
NCBI-ProteinID:
XP_034471122
LinkDB
All DBs
Position
18:16563226..16579598
Genome browser
AA seq
1070 aa
AA seq
DB search
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDEMRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLETFPLSQYKYIRSCITVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRCARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDVLVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSSGEAEQLRCLCSKDP
LYELSEQEKDFLWRHRHYCVKIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMIREFALRCLVKGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFDRFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
NT seq
3213 nt
NT seq
+upstream
nt +downstream
nt
atggcgcccaggccatcgtcaggggaactgtgggggctccatctgatgcccccccgcatc
ctggtagactgctgcctgcccaatgggatgatggtgagtcttgagtgtctcagagaaact
ccgctcatcagcatcaagcagcagctcttcactgaggccaggaaatatccactgtaccac
ttactgcaggaggagtcttgttacatttttgtgggcgtgacccaggaggcggagagggag
gagttttacgacgaaatgaggcggctctgtgacctccgactgtttcacccgatcctgaag
gtcatcgagccgctgggaaaccgggaggaaaagatcttgaaccgagagataggatttgcc
attgggatgcccgtctgcgagttcgagatgatgaaggacccggagattcaggacttccgg
cgctccatactgagcgtgtgccgagaggccatggaggagcgggaggggggcggggcccac
agccaggccctctatgtttatcctcccaacgtggagtccagcccacaactcccacagcac
atttacagcaaactggacaaagggaggctgattgttaccatatgggtgattgtgtctcct
tccaactccaaacagaaatacaccctgaaggtgagtcacgacagtttacctgagcagctg
atcgctgagtccatcaggaagaaaagtcgctctatgcatctttcacctcaacagctccgc
ctctgtgtccaggaataccagggccagtacatcctgaaggtgtgtggctgtgatgagtac
ctgttggagacgtttcctctcagtcagtacaagtatatccggtcctgtatcacggtgggt
cgtctccctcacctgatgctcgtctctaaagacagcctctactctcagttacctgcctct
ggcttcgtcacaccttcctacagtcgtcggactcctcagccgtccccctgtccaggaggg
ggcgatggttctcctcctcgctctctgtgggccttcaacactctgctgagggtccggctg
ctctgtgccacctacgtcaacgtcaacatccgcgacatcgacaagatctatgtccggacg
ggtatatatcacggtggtgaaccgctctgtgacaacgtcaacacacagagagttccgtgc
tccaaccccaggtggaatgagtggctgacctacgacatctacctggctgacttaccgcgc
tgtgcccgactctgcctgtcgatctgctctgtgaagggaaggaaaggagctaaggaggaa
cattgtcctctggcctgggggaacgtgaacctgtttgactataaggatgttctggtttcg
ggtaaagtggctctgagtctctggcctgttcctcacggcctcgaggatctacttaatccc
atcggagttgctggttcaaatcccaacaaagagacgccctgtgttgaactcgagttctct
tggttcaaccagacggtcgtttttcctgatgagcagcagattgaagaacacgccaactgg
accatcagccgagagctgggctataactactgccacggactgagcagtcgtctggcctgt
gacagcagtgtgtcctcaggcgaggctgagcagctccgttgtctttgttctaaagatcct
ctgtatgagctctcagagcaggagaaggacttcctctggagacacagacattactgtgta
aaaatcccagagtctcttccgaagcttcttctgtccgtcaagtggaactccagagacgaa
gtatcacagatgtactgtttgttgaaggagtggcccctgatggagccggagtccgctctg
gagttgttggactgtaactttcctgacccgatgatcagagagtttgctctgcgctgtctg
gtgaaaggcctgacagacgataagctgtcgcagtatctgctgcagctggttcaggtgttg
aagtatgagatgtacctggacaatcctcttgcacgtttcctgatcaagaaagctctgacc
aatcagagaattggtcactttttcttctggcatctcaagtcagagatgcacaataagact
gtgtctcgtcgtttcggtctgctgctggaagctttctgcagagcctgtgggatgtacctg
aaacatctgaacagacaggtggaggccatggacaagttggtgaacctgaccgacacattg
aaacaagaaaagaaggacgagacacagaaaacccagatgaagttcctggtcgaacacatg
tctcgacctgattacatggaggctctgcagggatttgtgtctcctctgaaccctgttcac
cagttgggaaacctcaggctggaggagtgtcggatcatgtcctcagcaaagcgccccctg
tggttgaactgggagaaccctgatatcatgtccgagctgcttttcacaaacaacgaaatc
atctttaagaatggagacgacctgcgtcaggacatgttgactctgcagatcattaagatc
atggagaacatctggcagaatcagggcctggacctgcgcatgctgccgtacgggtgcctg
tccattggagactgtgtcggtctgatcgaggtggtgaagaacagtttcaccatcatgcag
atccagtgtaaaggaggcctgaagggggcgctgcagttcaactccaacacgctgcaccac
tggatcaaagacaagaaccgaggagaggcgtatgaccgagccatcgacctcttcaccagg
tcgtgtgcaggttactgtgtcgccacgttcatcctgggaatcggagacagacacaactcc
aacatcatggtgaaggagaacggacagctgttccacattgacttcgggcacttcctggat
cataagaagaagaagtttgggtataagcgggagcgtgtccccttcgtcctgacgcaggac
ttcctcatcgtcatcagtaaaggaatccaggagtcgacaaagaccaaggagtttgacagg
ttccaggaaatgtgttacaaagcttatctcgccatccgtcagcacgccagcctcttcatc
aacctcttctccctcctcctcggctgcgggatgcctgaactgcagagctttgacgacatc
gcctacctgaggaagaccctcgctctggagaagagccagcaggaggcgttggagtatttc
accaaacagatgaacgatgctcaccatggaggctggagcacgaagatggactggatcttc
cacaccatcagacacatgcccaacgaacactga
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