Hyaena hyaena (striped hyena): 120220350
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Entry
120220350 CDS
T07257
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00020
Citrate cycle (TCA cycle)
hhv00480
Glutathione metabolism
hhv01100
Metabolic pathways
hhv01200
Carbon metabolism
hhv01210
2-Oxocarboxylic acid metabolism
hhv01230
Biosynthesis of amino acids
hhv04146
Peroxisome
hhv05230
Central carbon metabolism in cancer
Module
hhv_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hhv_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
120220350 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
120220350 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
120220350 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
120220350 (IDH2)
Enzymes [BR:
hhv01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
120220350 (IDH2)
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Paralog
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
120220350
NCBI-ProteinID:
XP_039073358
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All DBs
Position
Unknown
AA seq
451 aa
AA seq
DB search
MAGYLRVVRSLCRASGCGPAWAPAAPTGPSLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKIVFSPKDGSGAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atggccggctacctgcgcgtcgtgcgctcgctctgcagagcctccggctgcgggccggcc
tgggcgccggcggcccccacaggccccagcttgcaggagcagccgcggcgccactatgcc
gataagaggatcaaggtggcgaagccggtggtggagatggacggcgatgagatgacccgg
atcatctggcagttcatcaaggagaagctcatcctgccgcacgtggacgtccagctcaag
tattttgacctggggctcccaaaccgtgaccagaccaacgaccaggtcaccatagactcc
gcgttggccacccagaagtacagtgtggctgtcaaatgtgccaccatcacccccgatgaa
gcccgggtggaagagttcaagctgaagaagatgtggaagagtcccaatggaaccatccga
aacatcctaggagggaccgtcttccgggaacccatcatctgcaaaaacatcccacgcctc
gtcccgggctggaccaagcccatcaccatcggcaggcacgcccacggcgaccagtacaag
gctacagacttcgtggtcgaccgggccggcacgttcaagattgtcttctccccgaaggac
ggcagcggcgctaaggagtgggaggtgtacaatttcccggccggcggcgtggggatgggc
atgtataacacggatgagtccatctcaggctttgcacacagctgtttccagtacgccatc
cagaagaaatggccgctatacatgagcaccaagaacaccattctgaaggcctatgacggg
cgcttcaaggacatcttccaggaaatctttgagaagcactataagaccgacttcgacaag
aataagatctggtacgagcaccggctcatcgatgacatggtggctcaggtcctcaagtct
tcaggcggctttgtgtgggcctgcaagaactacgatggagatgtgcagtcggacatcctg
gcgcagggctttggctcccttggcctgatgacgtctgtgctggtctgcccggatgggaag
accattgaggctgaggctgctcatgggacggtcacccgccattatagggagcaccagaag
ggccggcctactagcaccaaccccatcgccagcatctttgcctggacgcgcggcctggag
caccggggaaagctggacgggaaccaggacctcatcaggtttgcacagaccctggagaag
gtgtgtgtccagacagtggagagcggagccatgaccaaggacctggccggctgcatccac
ggcctcagcaatgtgaagctcaacgagcacttcctgaacacgtcggacttcctggacacc
atcaagaacaacctggacaaggccctgggccagtag
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